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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 30

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20-Hydroxyeicosatetraenoic Acid (HETE)-dependent Hypertension in Human Cytochrome P450 (CYP) 4A11 Transgenic Mice: NORMALIZATION OF BLOOD PRESSURE BY SODIUM RESTRICTION, HYDROCHLOROTHIAZIDE, OR BLOCKADE OF THE TYPE 1 ANGIOTENSIN II RECEPTOR.
Savas Ü, Wei S, Hsu MH, Falck JR, Guengerich FP, Capdevila JH, Johnson EF
(2016) J Biol Chem 291: 16904-19
MeSH Terms: Angiotensins, Animals, Blood Pressure, Cytochrome P-450 CYP4A, Female, Humans, Hydroxyeicosatetraenoic Acids, Hypertension, Losartan, Male, Mice, Mice, Inbred BALB C, Mice, Transgenic, Receptor, Angiotensin, Type 1, Renin-Angiotensin System, Sodium Chloride, Dietary, Solute Carrier Family 12, Member 3
Added March 14, 2018
0 Communities
2 Members
0 Resources
17 MeSH Terms
Effects of losartan treatment on the physicochemical properties of diabetic rat bone.
Donmez BO, Unal M, Ozdemir S, Ozturk N, Oguz N, Akkus O
(2017) J Bone Miner Metab 35: 161-170
MeSH Terms: Absorptiometry, Photon, Angiotensin II Type 1 Receptor Blockers, Animals, Biomechanical Phenomena, Bone Density, Bone and Bones, Diabetes Mellitus, Experimental, Female, Losartan, Rats, Rats, Wistar, Renin-Angiotensin System, Spectroscopy, Fourier Transform Infrared
Added March 3, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
Atherosclerosis following renal injury is ameliorated by pioglitazone and losartan via macrophage phenotype.
Yamamoto S, Zhong J, Yancey PG, Zuo Y, Linton MF, Fazio S, Yang H, Narita I, Kon V
(2015) Atherosclerosis 242: 56-64
MeSH Terms: Angiotensin Receptor Antagonists, Animals, Aortic Diseases, Apolipoproteins E, Apoptosis, Atherosclerosis, Cell Line, Cytokines, Disease Models, Animal, Drug Evaluation, Preclinical, Drug Synergism, Drug Therapy, Combination, Female, Hyperlipidemias, Inflammation, Losartan, Macrophages, Mice, Mice, Inbred C57BL, Mice, Knockout, Nephrectomy, PPAR gamma, Phenotype, Pioglitazone, Renal Insufficiency, Chronic, Renin-Angiotensin System, Thiazolidinediones
Added April 10, 2018
0 Communities
1 Members
0 Resources
27 MeSH Terms
Estimated GFR decline as a surrogate end point for kidney failure: a post hoc analysis from the Reduction of End Points in Non-Insulin-Dependent Diabetes With the Angiotensin II Antagonist Losartan (RENAAL) study and Irbesartan Diabetic Nephropathy Trial (IDNT).
Lambers Heerspink HJ, Weldegiorgis M, Inker LA, Gansevoort R, Parving HH, Dwyer JP, Mondal H, Coresh J, Greene T, Levey AS, de Zeeuw D
(2014) Am J Kidney Dis 63: 244-50
MeSH Terms: Aged, Angiotensin II Type 1 Receptor Blockers, Biomarkers, Biphenyl Compounds, Diabetes Mellitus, Type 2, Double-Blind Method, Female, Glomerular Filtration Rate, Humans, Irbesartan, Kidney Failure, Chronic, Losartan, Male, Middle Aged, Tetrazoles
Added October 28, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Angiotensin II, independent of plasma renin activity, contributes to the hypertension of autonomic failure.
Arnold AC, Okamoto LE, Gamboa A, Shibao C, Raj SR, Robertson D, Biaggioni I
(2013) Hypertension 61: 701-6
MeSH Terms: Aged, Aldosterone, Angiotensin II, Angiotensin II Type 1 Receptor Blockers, Antihypertensive Agents, Captopril, Double-Blind Method, Female, Humans, Hypertension, Losartan, Male, Middle Aged, Orthostatic Intolerance, Pure Autonomic Failure, Renin, Sodium
Added December 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Losartan slows pancreatic tumor progression and extends survival of SPARC-null mice by abrogating aberrant TGFβ activation.
Arnold SA, Rivera LB, Carbon JG, Toombs JE, Chang CL, Bradshaw AD, Brekken RA
(2012) PLoS One 7: e31384
MeSH Terms: Angiotensin II Type 1 Receptor Blockers, Animals, Disease Progression, Extracellular Matrix, Losartan, Mice, Mice, Knockout, Neoplasm Invasiveness, Neoplasm Metastasis, Osteonectin, Pancreatic Neoplasms, Survival Rate, Transforming Growth Factor beta, Treatment Outcome
Added April 18, 2017
0 Communities
1 Members
0 Resources
14 MeSH Terms
Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials.
Holtkamp FA, de Zeeuw D, de Graeff PA, Laverman GD, Berl T, Remuzzi G, Packham D, Lewis JB, Parving HH, Lambers Heerspink HJ
(2011) Eur Heart J 32: 1493-9
MeSH Terms: Aged, Albuminuria, Amlodipine, Angiotensin Receptor Antagonists, Biphenyl Compounds, Blood Pressure, Calcium Channel Blockers, Cardiotonic Agents, Diabetes Mellitus, Type 2, Diabetic Angiopathies, Diabetic Nephropathies, Female, Heart Failure, Humans, Hypertension, Irbesartan, Losartan, Male, Middle Aged, Myocardial Infarction, Randomized Controlled Trials as Topic, Retrospective Studies, Risk Factors, Stroke, Tetrazoles, Treatment Outcome
Added December 10, 2013
0 Communities
1 Members
0 Resources
26 MeSH Terms
Effects of telmisartan, irbesartan, valsartan, candesartan, and losartan on cancers in 15 trials enrolling 138,769 individuals.
ARB Trialists Collaboration
(2011) J Hypertens 29: 623-35
MeSH Terms: Angiotensin-Converting Enzyme Inhibitors, Benzimidazoles, Benzoates, Biphenyl Compounds, Case-Control Studies, Double-Blind Method, Humans, Hypertension, Irbesartan, Losartan, Neoplasms, Randomized Controlled Trials as Topic, Telmisartan, Tetrazoles
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
Aliskiren in combination with losartan reduces albuminuria independent of baseline blood pressure in patients with type 2 diabetes and nephropathy.
Persson F, Lewis JB, Lewis EJ, Rossing P, Hollenberg NK, Parving HH
(2011) Clin J Am Soc Nephrol 6: 1025-31
MeSH Terms: Aged, Albuminuria, Amides, Antihypertensive Agents, Blood Pressure, Diabetes Mellitus, Type 2, Diabetic Nephropathies, Drug Therapy, Combination, Female, Fumarates, Humans, Hypertension, Renal, Losartan, Male, Middle Aged, Placebos, Treatment Outcome
Added December 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Impact of baseline renal function on the efficacy and safety of aliskiren added to losartan in patients with type 2 diabetes and nephropathy.
Persson F, Lewis JB, Lewis EJ, Rossing P, Hollenberg NK, Parving HH, AVOID Study Investigators
(2010) Diabetes Care 33: 2304-9
MeSH Terms: Aged, Albuminuria, Amides, Antihypertensive Agents, Creatinine, Diabetes Mellitus, Type 2, Diabetic Nephropathies, Female, Fumarates, Humans, Kidney Diseases, Kidney Function Tests, Losartan, Male, Middle Aged
Added December 10, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms