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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 38

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Structural, functional, and behavioral insights of dopamine dysfunction revealed by a deletion in .
Campbell NG, Shekar A, Aguilar JI, Peng D, Navratna V, Yang D, Morley AN, Duran AM, Galli G, O'Grady B, Ramachandran R, Sutcliffe JS, Sitte HH, Erreger K, Meiler J, Stockner T, Bellan LM, Matthies HJG, Gouaux E, Mchaourab HS, Galli A
(2019) Proc Natl Acad Sci U S A 116: 3853-3862
MeSH Terms: Animals, Animals, Genetically Modified, Autism Spectrum Disorder, Crystallography, X-Ray, Dopamine, Dopamine Plasma Membrane Transport Proteins, Drosophila melanogaster, Electron Spin Resonance Spectroscopy, Fear, Humans, Interpersonal Relations, Locomotion, Models, Molecular, Mutation, Sequence Deletion
Added March 18, 2020
0 Communities
2 Members
0 Resources
MeSH Terms
Serotonin transporter inhibition and 5-HT receptor activation drive loss of cocaine-induced locomotor activation in DAT Val559 mice.
Stewart A, Davis GL, Gresch PJ, Katamish RM, Peart R, Rabil MJ, Gowrishankar R, Carroll FI, Hahn MK, Blakely RD
(2019) Neuropsychopharmacology 44: 994-1006
MeSH Terms: Animals, Behavior, Animal, Cocaine, Conditioning, Classical, Disease Models, Animal, Dopamine, Dopamine Plasma Membrane Transport Proteins, Dopamine Uptake Inhibitors, Fluoxetine, Locomotion, Methylphenidate, Mice, Mice, 129 Strain, Mice, Inbred C57BL, Mice, Transgenic, Neostriatum, Receptor, Serotonin, 5-HT2C, Serotonin Plasma Membrane Transport Proteins, Serotonin Uptake Inhibitors
Added January 8, 2019
1 Communities
0 Members
0 Resources
19 MeSH Terms
Genetic loss of GluN2B in D1-expressing cell types enhances long-term cocaine reward and potentiation of thalamo-accumbens synapses.
Joffe ME, Turner BD, Delpire E, Grueter BA
(2018) Neuropsychopharmacology 43: 2383-2389
MeSH Terms: Animals, Cocaine, Gene Deletion, Locomotion, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Nucleus Accumbens, Receptors, Dopamine D1, Receptors, N-Methyl-D-Aspartate, Reward, Thalamus
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Therapeutic endocannabinoid augmentation for mood and anxiety disorders: comparative profiling of FAAH, MAGL and dual inhibitors.
Bedse G, Bluett RJ, Patrick TA, Romness NK, Gaulden AD, Kingsley PJ, Plath N, Marnett LJ, Patel S
(2018) Transl Psychiatry 8: 92
MeSH Terms: Amidohydrolases, Animals, Anti-Anxiety Agents, Anxiety Disorders, Behavior, Animal, Benzodioxoles, Body Temperature, Brain, Carbamates, Endocannabinoids, Female, Locomotion, Male, Maze Learning, Mice, Inbred C57BL, Mice, Inbred ICR, Monoacylglycerol Lipases, Piperazines, Piperidines, Pyridines, Stress, Psychological
Added April 12, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Muscarinic M receptors modulate ethanol seeking in rats.
Berizzi AE, Perry CJ, Shackleford DM, Lindsley CW, Jones CK, Chen NA, Sexton PM, Christopoulos A, Langmead CJ, Lawrence AJ
(2018) Neuropsychopharmacology 43: 1510-1517
MeSH Terms: Animals, Conditioning, Operant, Corpus Striatum, Cues, Drug-Seeking Behavior, Ethanol, Imidazoles, Indoles, Locomotion, Male, Microinjections, Rats, Receptor, Muscarinic M5, Self Administration, Sucrose, Varenicline
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Cholinergic Projections to the Substantia Nigra Pars Reticulata Inhibit Dopamine Modulation of Basal Ganglia through the M Muscarinic Receptor.
Moehle MS, Pancani T, Byun N, Yohn SE, Wilson GH, Dickerson JW, Remke DH, Xiang Z, Niswender CM, Wess J, Jones CK, Lindsley CW, Rook JM, Conn PJ
(2017) Neuron 96: 1358-1372.e4
MeSH Terms: Acetylcholine, Animals, Basal Ganglia, Channelrhodopsins, Choline O-Acetyltransferase, Cholinergic Agents, Cholinergic Neurons, Dopamine, Inhibitory Postsynaptic Potentials, Locomotion, Mice, Mice, Inbred C57BL, Mice, Transgenic, Neurotransmitter Agents, Oxygen, Pars Reticulata, Pedunculopontine Tegmental Nucleus, Receptor, Muscarinic M4, Receptors, Dopamine D1, Signal Transduction
Added March 14, 2018
0 Communities
4 Members
0 Resources
20 MeSH Terms
Functional Redundancy Between Canonical Endocannabinoid Signaling Systems in the Modulation of Anxiety.
Bedse G, Hartley ND, Neale E, Gaulden AD, Patrick TA, Kingsley PJ, Uddin MJ, Plath N, Marnett LJ, Patel S
(2017) Biol Psychiatry 82: 488-499
MeSH Terms: Adaptation, Ocular, Animals, Anti-Anxiety Agents, Anxiety, Arachidonic Acids, Benzodioxoles, Brain, Cannabinoid Receptor Agonists, Cyclohexanols, Disease Models, Animal, Dronabinol, Endocannabinoids, Excitatory Postsynaptic Potentials, Glycerides, Heterocyclic Compounds, 1-Ring, Locomotion, Male, Mice, Mice, Inbred ICR, Piperidines, Polyunsaturated Alkamides, Pyridines, Signal Transduction
Added April 26, 2017
0 Communities
3 Members
0 Resources
23 MeSH Terms
Arrestin-2 and arrestin-3 differentially modulate locomotor responses and sensitization to amphetamine.
Zurkovsky L, Sedaghat K, Ahmed MR, Gurevich VV, Gurevich EV
(2017) Neuropharmacology 121: 20-29
MeSH Terms: Amphetamine, Analysis of Variance, Animals, Arrestins, Central Nervous System Stimulants, Locomotion, Mice, Mice, Inbred C57BL, Mice, Knockout, Time Factors, beta-Arrestin 1
Added March 14, 2018
0 Communities
1 Members
0 Resources
11 MeSH Terms
Neuroendocrine modulation sustains the forward motor state.
Lim MA, Chitturi J, Laskova V, Meng J, Findeis D, Wiekenberg A, Mulcahy B, Luo L, Li Y, Lu Y, Hung W, Qu Y, Ho CY, Holmyard D, Ji N, McWhirter R, Samuel AD, Miller DM, Schnabel R, Calarco JA, Zhen M
(2016) Elife 5:
MeSH Terms: Animals, Behavior, Animal, Caenorhabditis elegans, Locomotion, Neural Pathways, Neurons, Neuropeptides, Neurosecretory Systems, Neurotransmitter Agents
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Discovery and SAR of novel series of imidazopyrimidinones and dihydroimidazopyrimidinones as positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5).
Martín-Martín ML, Bartolomé-Nebreda JM, Conde-Ceide S, Alonso de Diego SA, López S, Martínez-Viturro CM, Tong HM, Lavreysen H, Macdonald GJ, Steckler T, Mackie C, Bridges TM, Daniels JS, Niswender CM, Noetzel MJ, Jones CK, Conn PJ, Lindsley CW, Stauffer SR
(2015) Bioorg Med Chem Lett 25: 1310-7
MeSH Terms: Allosteric Regulation, Animals, Antipsychotic Agents, Brain, Drug Evaluation, Preclinical, Half-Life, Heterocyclic Compounds, 2-Ring, Humans, Imidazoles, Locomotion, Microsomes, Liver, Protein Binding, Pyrimidinones, Rats, Receptor, Metabotropic Glutamate 5, Structure-Activity Relationship
Added February 19, 2015
0 Communities
3 Members
0 Resources
16 MeSH Terms