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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 66

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Probing biophysical sequence constraints within the transmembrane domains of rhodopsin by deep mutational scanning.
Penn WD, McKee AG, Kuntz CP, Woods H, Nash V, Gruenhagen TC, Roushar FJ, Chandak M, Hemmerich C, Rusch DB, Meiler J, Schlebach JP
(2020) Sci Adv 6: eaay7505
MeSH Terms: Cell Membrane, Gene Expression, HEK293 Cells, Humans, Hydrophobic and Hydrophilic Interactions, Lipid Bilayers, Models, Molecular, Mutation, Protein Domains, Protein Folding, Protein Structure, Secondary, Recombinant Proteins, Rhodopsin, Solubility, Thermodynamics
Added March 21, 2020
0 Communities
1 Members
0 Resources
15 MeSH Terms
Peripheral myelin protein 22 alters membrane architecture.
Mittendorf KF, Marinko JT, Hampton CM, Ke Z, Hadziselimovic A, Schlebach JP, Law CL, Li J, Wright ER, Sanders CR, Ohi MD
(2017) Sci Adv 3: e1700220
MeSH Terms: Cell Membrane, Charcot-Marie-Tooth Disease, Cysteine, Humans, Lipid Bilayers, Lipids, Liposomes, Mutation, Myelin Proteins, Recombinant Proteins
Added November 21, 2018
0 Communities
2 Members
0 Resources
10 MeSH Terms
Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes.
Zurawski Z, Page B, Chicka MC, Brindley RL, Wells CA, Preininger AM, Hyde K, Gilbert JA, Cruz-Rodriguez O, Currie KPM, Chapman ER, Alford S, Hamm HE
(2017) J Biol Chem 292: 12165-12177
MeSH Terms: Animals, Binding, Competitive, Calcium Signaling, Cattle, Cell Line, GTP-Binding Protein beta Subunits, GTP-Binding Protein gamma Subunits, Humans, Lipid Bilayers, Liposomes, Membrane Fusion, Models, Molecular, Mutation, Nerve Tissue Proteins, Peptide Fragments, Protein Conformation, Protein Interaction Domains and Motifs, Protein Multimerization, Rats, Recombinant Fusion Proteins, Recombinant Proteins, Synaptosomal-Associated Protein 25, Synaptotagmin I, Syntaxin 1
Added July 12, 2017
0 Communities
2 Members
0 Resources
24 MeSH Terms
Investigating the Structure of Multicomponent Gel-Phase Lipid Bilayers.
Hartkamp R, Moore TC, Iacovella CR, Thompson MA, Bulsara PA, Moore DJ, McCabe C
(2016) Biophys J 111: 813-823
MeSH Terms: Gels, Hydrogen Bonding, Lipid Bilayers, Models, Molecular, Molecular Conformation, Water
Added May 3, 2017
0 Communities
1 Members
0 Resources
6 MeSH Terms
Structural organization of membrane-inserted hexamers formed by Helicobacter pylori VacA toxin.
Pyburn TM, Foegeding NJ, González-Rivera C, McDonald NA, Gould KL, Cover TL, Ohi MD
(2016) Mol Microbiol 102: 22-36
MeSH Terms: Bacterial Proteins, Cytotoxins, HeLa Cells, Helicobacter pylori, Humans, Lipid Bilayers, Membrane Proteins, Protein Conformation, Protein Domains, Structure-Activity Relationship, Vacuoles
Added September 29, 2016
0 Communities
3 Members
0 Resources
11 MeSH Terms
Probing Structural Dynamics and Topology of the KCNE1 Membrane Protein in Lipid Bilayers via Site-Directed Spin Labeling and Electron Paramagnetic Resonance Spectroscopy.
Sahu ID, Craig AF, Dunagan MM, Troxel KR, Zhang R, Meiberg AG, Harmon CN, McCarrick RM, Kroncke BM, Sanders CR, Lorigan GA
(2015) Biochemistry 54: 6402-12
MeSH Terms: Amino Acid Sequence, Electron Spin Resonance Spectroscopy, Lipid Bilayers, Molecular Dynamics Simulation, Molecular Sequence Data, Mutagenesis, Site-Directed, Potassium Channels, Voltage-Gated, Protein Conformation
Added November 21, 2018
0 Communities
3 Members
0 Resources
MeSH Terms
Development of electron spin echo envelope modulation spectroscopy to probe the secondary structure of recombinant membrane proteins in a lipid bilayer.
Zhang R, Sahu ID, Gibson KR, Muhammad NB, Bali AP, Comer RG, Liu L, Craig AF, Mccarrick RM, Dabney-Smith C, Sanders CR, Lorigan GA
(2015) Protein Sci 24: 1707-13
MeSH Terms: Electron Spin Resonance Spectroscopy, Humans, Lipid Bilayers, Membrane Proteins, Models, Molecular, Potassium Channels, Voltage-Gated, Protein Structure, Secondary
Added November 21, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Notch Transmembrane Domain: Secondary Structure and Topology.
Deatherage CL, Lu Z, Kim JH, Sanders CR
(2015) Biochemistry 54: 3565-8
MeSH Terms: Humans, Lipid Bilayers, Lysophosphatidylcholines, Models, Molecular, Nuclear Magnetic Resonance, Biomolecular, Peptide Fragments, Phosphatidylcholines, Protein Conformation, Protein Structure, Secondary, Protein Structure, Tertiary, Receptor, Notch1, Recombinant Proteins, Surface Properties
Added February 5, 2016
1 Communities
1 Members
0 Resources
13 MeSH Terms
Functional stability of rhodopsin in a bicelle system: evaluating G protein activation by rhodopsin in bicelles.
Kaya AI, Iverson TM, Hamm HE
(2015) Methods Mol Biol 1271: 67-76
MeSH Terms: Cell Membrane, GTP-Binding Proteins, Lipid Bilayers, Phospholipids, Rhodopsin
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Structural investigation of the transmembrane domain of KCNE1 in proteoliposomes.
Sahu ID, Kroncke BM, Zhang R, Dunagan MM, Smith HJ, Craig A, McCarrick RM, Sanders CR, Lorigan GA
(2014) Biochemistry 53: 6392-401
MeSH Terms: Amino Acid Substitution, Humans, Lipid Bilayers, Liposomes, Molecular Dynamics Simulation, Phosphatidylcholines, Phosphatidylglycerols, Potassium Channels, Voltage-Gated, Protein Structure, Secondary, Protein Structure, Tertiary, Thermodynamics
Added November 21, 2018
0 Communities
1 Members
0 Resources
MeSH Terms