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Results: 1 to 10 of 28

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Isolation and characterization of two geometric allene oxide isomers synthesized from 9S-hydroperoxylinoleic acid by cytochrome P450 CYP74C3: stereochemical assignment of natural fatty acid allene oxides.
Brash AR, Boeglin WE, Stec DF, Voehler M, Schneider C, Cha JK
(2013) J Biol Chem 288: 20797-20806
MeSH Terms: Chromatography, High Pressure Liquid, Chromatography, Reverse-Phase, Cyclization, Cyclopentanes, Cytochrome P-450 Enzyme System, Epoxy Compounds, Flax, Linoleic Acids, Magnetic Resonance Spectroscopy, Molecular Conformation, Oxylipins, Stereoisomerism
Added March 7, 2014
0 Communities
3 Members
0 Resources
12 MeSH Terms
Cytochrome P450-type hydroxylation and epoxidation in a tyrosine-liganded hemoprotein, catalase-related allene oxide synthase.
Boeglin WE, Brash AR
(2012) J Biol Chem 287: 24139-47
MeSH Terms: Catalase, Chromatography, High Pressure Liquid, Cytochrome P-450 Enzyme System, Gas Chromatography-Mass Spectrometry, Hemeproteins, Hydroxylation, Intramolecular Oxidoreductases, Iodobenzenes, Linoleic Acids, Magnetic Resonance Spectroscopy
Added January 21, 2015
0 Communities
1 Members
0 Resources
10 MeSH Terms
Cyclooxygenases and lipoxygenases in cancer.
Schneider C, Pozzi A
(2011) Cancer Metastasis Rev 30: 277-94
MeSH Terms: Animals, Antineoplastic Agents, Arachidonate Lipoxygenases, Cell Transformation, Neoplastic, Cyclooxygenase Inhibitors, Eicosanoids, Humans, Linoleic Acids, Neoplasms, Prostaglandin-Endoperoxide Synthases
Added February 24, 2014
0 Communities
2 Members
1 Resources
10 MeSH Terms
Tyrosine-lipid peroxide adducts from radical termination: para coupling and intramolecular Diels-Alder cyclization.
Shchepin R, Möller MN, Kim HY, Hatch DM, Bartesaghi S, Kalyanaraman B, Radi R, Porter NA
(2010) J Am Chem Soc 132: 17490-500
MeSH Terms: Chromatography, High Pressure Liquid, Cyclization, Cycloaddition Reaction, Free Radicals, Linoleic Acids, Lipid Peroxides, Mass Spectrometry, Oxidation-Reduction, Peroxides, Phosphatidylcholines, Silver, Tyrosine
Added May 29, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms
Dietary fat decreases intestinal levels of the anorectic lipids through a fat sensor.
Diep TA, Madsen AN, Holst B, Kristiansen MM, Wellner N, Hansen SH, Hansen HS
(2011) FASEB J 25: 765-74
MeSH Terms: Animals, Dietary Fats, Dose-Response Relationship, Drug, Eating, Gene Expression Regulation, Enzymologic, Intestinal Mucosa, Intestines, Linoleic Acids, Lipids, Male, Polyunsaturated Alkamides, RNA, Messenger, Random Allocation, Rats, Rats, Sprague-Dawley
Added April 10, 2014
0 Communities
0 Members
1 Resources
15 MeSH Terms
On the role of molecular oxygen in lipoxygenase activation: comparison and contrast of epidermal lipoxygenase-3 with soybean lipoxygenase-1.
Zheng Y, Brash AR
(2010) J Biol Chem 285: 39876-87
MeSH Terms: Catalytic Domain, Enzyme Activation, Humans, Hydrogen Peroxide, Linoleic Acids, Lipoxygenase, Mutation, Missense, Oxygen, Plant Proteins, Soybeans, Species Specificity
Added December 10, 2013
0 Communities
1 Members
0 Resources
11 MeSH Terms
Ex vivo oxidation in tissue and plasma assays of hydroxyoctadecadienoates: Z,E/E,E stereoisomer ratios.
Liu W, Yin H, Akazawa YO, Yoshida Y, Niki E, Porter NA
(2010) Chem Res Toxicol 23: 986-95
MeSH Terms: Animals, Borohydrides, Chromatography, High Pressure Liquid, Female, Gas Chromatography-Mass Spectrometry, Linoleic Acids, Linoleic Acids, Conjugated, Mice, Mice, Inbred BALB C, Organophosphorus Compounds, Oxidation-Reduction, Stereoisomerism, Tandem Mass Spectrometry
Added March 7, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis.
Ashwell MS, Ceddia RP, House RL, Cassady JP, Eisen EJ, Eling TE, Collins JB, Grissom SF, Odle J
(2010) J Nutr Biochem 21: 848-55
MeSH Terms: Animals, Fatty Liver, Gene Expression Profiling, Hepatocyte Nuclear Factor 4, Linoleic Acids, Conjugated, Liver, Male, Mice, Obesity
Added September 25, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Enzymatic synthesis of a bicyclobutane fatty acid by a hemoprotein lipoxygenase fusion protein from the cyanobacterium Anabaena PCC 7120.
Schneider C, Niisuke K, Boeglin WE, Voehler M, Stec DF, Porter NA, Brash AR
(2007) Proc Natl Acad Sci U S A 104: 18941-5
MeSH Terms: Anabaena, Bacterial Proteins, Catalase, Chromatography, High Pressure Liquid, Conserved Sequence, Epoxy Compounds, Hemeproteins, Hexanes, Leukotriene A4, Linoleic Acids, Linolenic Acids, Lipoxygenase, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Oleic Acids, Peptide Fragments, Peroxidases, Protein Structure, Tertiary, Recombinant Proteins, Sequence Homology, Amino Acid, Spectrophotometry, Ultraviolet
Added December 10, 2013
0 Communities
4 Members
0 Resources
21 MeSH Terms
Identification of the peroxidation products of 13-hydroxy-gamma-linolenate and 15-hydroxyarachidonate: mechanistic studies on the formation of leukotriene-like diols.
Rector CL, Stec DF, Brash AR, Porter NA
(2007) Chem Res Toxicol 20: 1582-93
MeSH Terms: Arachidonic Acids, Chromatography, High Pressure Liquid, Leukotrienes, Linoleic Acids, Lipid Peroxidation, Magnetic Resonance Spectroscopy, Mass Spectrometry, Oxidation-Reduction
Added December 10, 2013
0 Communities
3 Members
0 Resources
8 MeSH Terms