Isolation and characterization of two geometric allene oxide isomers synthesized from 9S-hydroperoxylinoleic acid by cytochrome P450 CYP74C3: stereochemical assignment of natural fatty acid allene oxides.
Brash AR, Boeglin WE, Stec DF, Voehler M, Schneider C, Cha JK
(2013) J Biol Chem 288
: 20797-20806MeSH Terms: Chromatography, High Pressure Liquid, Chromatography, Reverse-Phase, Cyclization, Cyclopentanes, Cytochrome P-450 Enzyme System, Epoxy Compounds, Flax, Linoleic Acids, Magnetic Resonance Spectroscopy, Molecular Conformation, Oxylipins, StereoisomerismAdded March 7, 2014
12 MeSH Terms
Cytochrome P450-type hydroxylation and epoxidation in a tyrosine-liganded hemoprotein, catalase-related allene oxide synthase.
Boeglin WE, Brash AR
(2012) J Biol Chem 287
: 24139-47MeSH Terms: Catalase, Chromatography, High Pressure Liquid, Cytochrome P-450 Enzyme System, Gas Chromatography-Mass Spectrometry, Hemeproteins, Hydroxylation, Intramolecular Oxidoreductases, Iodobenzenes, Linoleic Acids, Magnetic Resonance SpectroscopyAdded January 21, 2015
10 MeSH Terms
Cyclooxygenases and lipoxygenases in cancer.
Schneider C, Pozzi A
(2011) Cancer Metastasis Rev 30
: 277-94MeSH Terms: Animals, Antineoplastic Agents, Arachidonate Lipoxygenases, Cell Transformation, Neoplastic, Cyclooxygenase Inhibitors, Eicosanoids, Humans, Linoleic Acids, Neoplasms, Prostaglandin-Endoperoxide SynthasesAdded February 24, 2014
10 MeSH Terms
Tyrosine-lipid peroxide adducts from radical termination: para coupling and intramolecular Diels-Alder cyclization.
Shchepin R, Möller MN, Kim HY, Hatch DM, Bartesaghi S, Kalyanaraman B, Radi R, Porter NA
(2010) J Am Chem Soc 132
: 17490-500MeSH Terms: Chromatography, High Pressure Liquid, Cyclization, Cycloaddition Reaction, Free Radicals, Linoleic Acids, Lipid Peroxides, Mass Spectrometry, Oxidation-Reduction, Peroxides, Phosphatidylcholines, Silver, TyrosineAdded May 29, 2014
12 MeSH Terms
Dietary fat decreases intestinal levels of the anorectic lipids through a fat sensor.
Diep TA, Madsen AN, Holst B, Kristiansen MM, Wellner N, Hansen SH, Hansen HS
(2011) FASEB J 25
: 765-74MeSH Terms: Animals, Dietary Fats, Dose-Response Relationship, Drug, Eating, Gene Expression Regulation, Enzymologic, Intestinal Mucosa, Intestines, Linoleic Acids, Lipids, Male, Polyunsaturated Alkamides, RNA, Messenger, Random Allocation, Rats, Rats, Sprague-DawleyAdded April 10, 2014
15 MeSH Terms
On the role of molecular oxygen in lipoxygenase activation: comparison and contrast of epidermal lipoxygenase-3 with soybean lipoxygenase-1.
Zheng Y, Brash AR
(2010) J Biol Chem 285
: 39876-87MeSH Terms: Catalytic Domain, Enzyme Activation, Humans, Hydrogen Peroxide, Linoleic Acids, Lipoxygenase, Mutation, Missense, Oxygen, Plant Proteins, Soybeans, Species SpecificityAdded December 10, 2013
11 MeSH Terms
Ex vivo oxidation in tissue and plasma assays of hydroxyoctadecadienoates: Z,E/E,E stereoisomer ratios.
Liu W, Yin H, Akazawa YO, Yoshida Y, Niki E, Porter NA
(2010) Chem Res Toxicol 23
: 986-95MeSH Terms: Animals, Borohydrides, Chromatography, High Pressure Liquid, Female, Gas Chromatography-Mass Spectrometry, Linoleic Acids, Linoleic Acids, Conjugated, Mice, Mice, Inbred BALB C, Organophosphorus Compounds, Oxidation-Reduction, Stereoisomerism, Tandem Mass SpectrometryAdded March 7, 2014
13 MeSH Terms
Trans-10, cis-12-conjugated linoleic acid alters hepatic gene expression in a polygenic obese line of mice displaying hepatic lipidosis.
Ashwell MS, Ceddia RP, House RL, Cassady JP, Eisen EJ, Eling TE, Collins JB, Grissom SF, Odle J
(2010) J Nutr Biochem 21
: 848-55MeSH Terms: Animals, Fatty Liver, Gene Expression Profiling, Hepatocyte Nuclear Factor 4, Linoleic Acids, Conjugated, Liver, Male, Mice, ObesityAdded September 25, 2018
Enzymatic synthesis of a bicyclobutane fatty acid by a hemoprotein lipoxygenase fusion protein from the cyanobacterium Anabaena PCC 7120.
Schneider C, Niisuke K, Boeglin WE, Voehler M, Stec DF, Porter NA, Brash AR
(2007) Proc Natl Acad Sci U S A 104
: 18941-5MeSH Terms: Anabaena, Bacterial Proteins, Catalase, Chromatography, High Pressure Liquid, Conserved Sequence, Epoxy Compounds, Hemeproteins, Hexanes, Leukotriene A4, Linoleic Acids, Linolenic Acids, Lipoxygenase, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Oleic Acids, Peptide Fragments, Peroxidases, Protein Structure, Tertiary, Recombinant Proteins, Sequence Homology, Amino Acid, Spectrophotometry, UltravioletAdded December 10, 2013
21 MeSH Terms
Identification of the peroxidation products of 13-hydroxy-gamma-linolenate and 15-hydroxyarachidonate: mechanistic studies on the formation of leukotriene-like diols.
Rector CL, Stec DF, Brash AR, Porter NA
(2007) Chem Res Toxicol 20
: 1582-93MeSH Terms: Arachidonic Acids, Chromatography, High Pressure Liquid, Leukotrienes, Linoleic Acids, Lipid Peroxidation, Magnetic Resonance Spectroscopy, Mass Spectrometry, Oxidation-ReductionAdded December 10, 2013
8 MeSH Terms