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TNF-receptor 1 deficiency fails to alter the clinical and pathological course in mice with globoid cell leukodystrophy (twitcher mice) but affords protection following LPS challenge.
Pedchenko TV, Bronshteyn IG, LeVine SM
(2000) J Neuroimmunol 110: 186-94
MeSH Terms: Animals, Blood-Brain Barrier, Brain, Demyelinating Diseases, Disease Models, Animal, Galactosylceramidase, Immune System, Leukodystrophy, Globoid Cell, Lipopolysaccharides, Lysosomes, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Neurologic Mutants, Oligodendroglia, Organ Size, Receptors, Tumor Necrosis Factor, Sciatic Nerve
Added March 5, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
L-cycloserine slows the clinical and pathological course in mice with globoid cell leukodystrophy (twitcher mice).
LeVine SM, Pedchenko TV, Bronshteyn IG, Pinson DM
(2000) J Neurosci Res 60: 231-6
MeSH Terms: Animals, Brain, Cycloserine, Leukodystrophy, Globoid Cell, Mice, Mice, Mutant Strains
Added March 5, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
IL-6 deficiency causes enhanced pathology in Twitcher (globoid cell leukodystrophy) mice.
Pedchenko TV, LeVine SM
(1999) Exp Neurol 158: 459-68
MeSH Terms: Animals, Blood-Brain Barrier, Brain, Crosses, Genetic, Disease Progression, Escherichia coli, Glial Fibrillary Acidic Protein, Interleukin-6, Lectins, Leukodystrophy, Globoid Cell, Lipopolysaccharides, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Neurologic Mutants, Motor Activity, Myelin Basic Protein, Rhombencephalon, Tumor Necrosis Factor-alpha
Added March 5, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms