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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 19

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Cyclin G1 and TASCC regulate kidney epithelial cell G-M arrest and fibrotic maladaptive repair.
Canaud G, Brooks CR, Kishi S, Taguchi K, Nishimura K, Magassa S, Scott A, Hsiao LL, Ichimura T, Terzi F, Yang L, Bonventre JV
(2019) Sci Transl Med 11:
MeSH Terms: Animals, Autophagy, Cell Compartmentation, Cell Cycle Checkpoints, Cell Dedifferentiation, Cyclin G1, Disease Models, Animal, Disease Progression, Epithelial Cells, Fibrosis, Humans, Kidney, Kidney Tubules, Proximal, LLC-PK1 Cells, Male, Mice, Renal Insufficiency, Chronic, Swine, TOR Serine-Threonine Kinases, Wound Healing
Added March 14, 2019
0 Communities
1 Members
0 Resources
20 MeSH Terms
Myosin-7b Promotes Distal Tip Localization of the Intermicrovillar Adhesion Complex.
Weck ML, Crawley SW, Stone CR, Tyska MJ
(2016) Curr Biol 26: 2717-2728
MeSH Terms: Animals, Caco-2 Cells, Epithelial Cells, Humans, LLC-PK1 Cells, Microvilli, Myosin Heavy Chains, Swine
Added April 7, 2017
1 Communities
1 Members
0 Resources
8 MeSH Terms
Meclizine Preconditioning Protects the Kidney Against Ischemia-Reperfusion Injury.
Kishi S, Campanholle G, Gohil VM, Perocchi F, Brooks CR, Morizane R, Sabbisetti V, Ichimura T, Mootha VK, Bonventre JV
(2015) EBioMedicine 2: 1090-101
MeSH Terms: Acute Kidney Injury, Adenosine Triphosphate, Animals, Cell Respiration, Cytochromes c, Deoxyglucose, Disease Models, Animal, Epithelial Cells, Ethanolamines, Galactose, Glycolysis, Humans, Inflammation, Ischemic Preconditioning, Kidney, Kidney Tubules, L-Lactate Dehydrogenase, LLC-PK1 Cells, Male, Meclizine, Mice, Inbred C57BL, Mitochondria, Protective Agents, Reperfusion Injury, Sodium Cyanide, Swine, Up-Regulation
Added September 12, 2016
1 Communities
1 Members
0 Resources
27 MeSH Terms
KIM-1-mediated phagocytosis reduces acute injury to the kidney.
Yang L, Brooks CR, Xiao S, Sabbisetti V, Yeung MY, Hsiao LL, Ichimura T, Kuchroo V, Bonventre JV
(2015) J Clin Invest 125: 1620-36
MeSH Terms: Acute Kidney Injury, Animals, Apoptosis, Cisplatin, Cytokines, Epithelial Cells, Extracellular Matrix Proteins, Gene Expression Regulation, Hepatitis A Virus Cellular Receptor 1, Homeodomain Proteins, Immunity, Innate, Inflammation, Intercellular Signaling Peptides and Proteins, Kidney, Kidney Tubules, Proximal, LLC-PK1 Cells, Macrophage Activation, Male, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, NF-kappa B, Phagocytosis, Phosphatidylinositol 3-Kinases, Protein Structure, Tertiary, Radiation Chimera, Reperfusion Injury, Swine
Added September 12, 2016
1 Communities
1 Members
0 Resources
29 MeSH Terms
Myosin-1A targets to microvilli using multiple membrane binding motifs in the tail homology 1 (TH1) domain.
Mazerik JN, Tyska MJ
(2012) J Biol Chem 287: 13104-15
MeSH Terms: Acids, Animals, Epithelial Cells, Green Fluorescent Proteins, Humans, Intestinal Mucosa, LLC-PK1 Cells, Liposomes, Membrane Proteins, Microvilli, Myosin Heavy Chains, Myosin Type I, Phospholipids, Protein Structure, Tertiary, Swine
Added May 19, 2014
1 Communities
1 Members
0 Resources
15 MeSH Terms
EGFR signaling promotes TGFβ-dependent renal fibrosis.
Chen J, Chen JK, Nagai K, Plieth D, Tan M, Lee TC, Threadgill DW, Neilson EG, Harris RC
(2012) J Am Soc Nephrol 23: 215-24
MeSH Terms: Angiotensin II, Animals, ErbB Receptors, Extracellular Signal-Regulated MAP Kinases, Fibrosis, Kidney, LLC-PK1 Cells, Male, Mice, Mice, Inbred BALB C, Phosphorylation, Reactive Oxygen Species, Signal Transduction, Smad2 Protein, Smad3 Protein, Swine, Transforming Growth Factor beta
Added August 19, 2013
1 Communities
1 Members
0 Resources
17 MeSH Terms
A common 5'-UTR variant in MATE2-K is associated with poor response to metformin.
Choi JH, Yee SW, Ramirez AH, Morrissey KM, Jang GH, Joski PJ, Mefford JA, Hesselson SE, Schlessinger A, Jenkins G, Castro RA, Johns SJ, Stryke D, Sali A, Ferrin TE, Witte JS, Kwok PY, Roden DM, Wilke RA, McCarty CA, Davis RL, Giacomini KM
(2011) Clin Pharmacol Ther 90: 674-84
MeSH Terms: Adult, Aged, Alleles, Animals, Diabetes Mellitus, Type 2, Female, Genetic Variation, Glycated Hemoglobin A, HCT116 Cells, HEK293 Cells, Haplotypes, Humans, Hypoglycemic Agents, LLC-PK1 Cells, Luciferases, Male, Metformin, Middle Aged, Organic Cation Transport Proteins, Polymorphism, Genetic, Promoter Regions, Genetic, Racial Groups, Retrospective Studies, Swine, Treatment Outcome
Added June 26, 2014
0 Communities
1 Members
0 Resources
25 MeSH Terms
Identification of a novel mono-leucine basolateral sorting motif within the cytoplasmic domain of amphiregulin.
Gephart JD, Singh B, Higginbotham JN, Franklin JL, Gonzalez A, Fölsch H, Coffey RJ
(2011) Traffic 12: 1793-804
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Amphiregulin, Animals, Cell Line, Cell Membrane, Cell Polarity, Cytoplasm, Dogs, EGF Family of Proteins, Epithelial Cells, ErbB Receptors, Glycoproteins, Humans, Intercellular Signaling Peptides and Proteins, LLC-PK1 Cells, Leucine, Membrane Proteins, Molecular Sequence Data, Protein Structure, Tertiary, Protein Transport, Receptors, Nerve Growth Factor, Swine
Added December 5, 2013
2 Communities
3 Members
0 Resources
23 MeSH Terms
Development and characterization of LLC-PK1 cells containing Sprague-Dawley rat Abcb1a (Mdr1a): comparison of rat P-glycoprotein transport to human and mouse.
Booth-Genthe CL, Louie SW, Carlini EJ, Li B, Leake BF, Eisenhandler R, Hochman JH, Mei Q, Kim RB, Rushmore TH, Yamazaki M
(2006) J Pharmacol Toxicol Methods 54: 78-89
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, ATP Binding Cassette Transporter, Subfamily B, Member 1, ATP-Binding Cassette Transporters, Amino Acid Sequence, Animals, Cloning, Molecular, Humans, LLC-PK1 Cells, Mice, Molecular Sequence Data, Protein Transport, Rats, Rats, Sprague-Dawley, Species Specificity
Added March 27, 2014
1 Communities
1 Members
2 Resources
14 MeSH Terms
Tyr-95 and Ile-172 in transmembrane segments 1 and 3 of human serotonin transporters interact to establish high affinity recognition of antidepressants.
Henry LK, Field JR, Adkins EM, Parnas ML, Vaughan RA, Zou MF, Newman AH, Blakely RD
(2006) J Biol Chem 281: 2012-23
MeSH Terms: Adrenergic Uptake Inhibitors, Amino Acid Sequence, Animals, Antidepressive Agents, Binding Sites, Binding, Competitive, Blotting, Western, Cadmium, Cell Line, Cell Membrane, Citalopram, Clomipramine, Cocaine, Cysteine, Dopamine Uptake Inhibitors, Fluoxetine, HeLa Cells, Humans, Immunoprecipitation, Isoleucine, Kinetics, LLC-PK1 Cells, Mazindol, Methionine, Mice, Models, Chemical, Molecular Sequence Data, Mutation, N-Methyl-3,4-methylenedioxyamphetamine, Nomifensine, Protein Binding, Protein Structure, Tertiary, Protein Transport, Radiopharmaceuticals, Receptors, Serotonin, Serotonin, Serotonin Uptake Inhibitors, Species Specificity, Stereoisomerism, Substrate Specificity, Tyrosine
Added July 10, 2013
2 Communities
1 Members
0 Resources
41 MeSH Terms