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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 22

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The LIM protein complex establishes a retinal circuitry of visual adaptation by regulating Pax6 α-enhancer activity.
Kim Y, Lim S, Ha T, Song YH, Sohn YI, Park DJ, Paik SS, Kim-Kaneyama JR, Song MR, Leung A, Levine EM, Kim IB, Goo YS, Lee SH, Kang KH, Kim JW
(2017) Elife 6:
MeSH Terms: Adaptation, Ocular, Animals, Cytoskeletal Proteins, DNA-Binding Proteins, Enhancer Elements, Genetic, Gene Expression Regulation, LIM Domain Proteins, LIM-Homeodomain Proteins, Mice, Mice, Knockout, PAX6 Transcription Factor, Retina, Transcription Factors
Added February 14, 2018
0 Communities
1 Members
0 Resources
13 MeSH Terms
LIM-Only Protein 4 (LMO4) and LIM Domain Binding Protein 1 (LDB1) Promote Growth and Metastasis of Human Head and Neck Cancer (LMO4 and LDB1 in Head and Neck Cancer).
Simonik EA, Cai Y, Kimmelshue KN, Brantley-Sieders DM, Loomans HA, Andl CD, Westlake GM, Youngblood VM, Chen J, Yarbrough WG, Brown BT, Nagarajan L, Brandt SJ
(2016) PLoS One 11: e0164804
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Carcinoma, Squamous Cell, Cell Line, Tumor, Cell Movement, Cell Proliferation, DNA-Binding Proteins, Gene Expression Regulation, Neoplastic, Humans, LIM Domain Proteins, Mice, Mouth Neoplasms, Neoplasm Metastasis, Neoplasm Transplantation, Tissue Culture Techniques, Transcription Factors
Added March 29, 2017
1 Communities
1 Members
0 Resources
16 MeSH Terms
LMO2 Oncoprotein Stability in T-Cell Leukemia Requires Direct LDB1 Binding.
Layer JH, Alford CE, McDonald WH, Davé UP
(2016) Mol Cell Biol 36: 488-506
MeSH Terms: Adaptor Proteins, Signal Transducing, Amino Acid Sequence, Amino Acid Substitution, Cell Line, DNA-Binding Proteins, Humans, Jurkat Cells, LIM Domain Proteins, Leukemia, T-Cell, Molecular Sequence Data, Mutation, Protein Interaction Domains and Motifs, Protein Interaction Maps, Protein Stability, Proto-Oncogene Proteins, Transcription Factors, Transcriptional Activation
Added January 26, 2016
0 Communities
2 Members
0 Resources
17 MeSH Terms
LASP-1: a nuclear hub for the UHRF1-DNMT1-G9a-Snail1 complex.
Duvall-Noelle N, Karwandyar A, Richmond A, Raman D
(2016) Oncogene 35: 1122-33
MeSH Terms: Active Transport, Cell Nucleus, Adaptor Proteins, Signal Transducing, Benzylamines, Breast Neoplasms, CCAAT-Enhancer-Binding Proteins, Cell Line, Tumor, Chemokine CXCL12, Cyclams, Cytoskeletal Proteins, DNA (Cytosine-5-)-Methyltransferase 1, DNA (Cytosine-5-)-Methyltransferases, Epigenesis, Genetic, Gene Knockdown Techniques, Heterocyclic Compounds, Histocompatibility Antigens, Histone-Lysine N-Methyltransferase, Histones, Humans, LIM Domain Proteins, Prognosis, Proteomics, Signal Transduction, Snail Family Transcription Factors, Transcription Factors, Tumor Microenvironment, Ubiquitin-Protein Ligases
Added May 20, 2015
2 Communities
2 Members
0 Resources
26 MeSH Terms
The focal adhesion protein PINCH-1 associates with EPLIN at integrin adhesion sites.
Karaköse E, Geiger T, Flynn K, Lorenz-Baath K, Zent R, Mann M, Fässler R
(2015) J Cell Sci 128: 1023-33
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Cell Movement, Cells, Cultured, Cytoskeletal Proteins, Focal Adhesions, Integrins, Keratinocytes, LIM Domain Proteins, Male, Membrane Proteins, Mice, Mice, Transgenic
Added February 4, 2016
1 Communities
1 Members
0 Resources
13 MeSH Terms
Enforced expression of E47 has differential effects on Lmo2-induced T-cell leukemias.
Goodings C, Tripathi R, Cleveland SM, Elliott N, Guo Y, Shyr Y, Davé UP
(2015) Leuk Res 39: 100-9
MeSH Terms: Adaptor Proteins, Signal Transducing, Basic Helix-Loop-Helix Transcription Factors, Cell Cycle Checkpoints, Cell Line, Tumor, Cell Transformation, Neoplastic, Humans, LIM Domain Proteins, Leukemia, T-Cell, Protein Multimerization, Proto-Oncogene Proteins, Response Elements, Transcription Factor 3
Added February 19, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
LMO2 induces T-cell leukemia with epigenetic deregulation of CD4.
Cleveland SM, Goodings C, Tripathi RM, Elliott N, Thompson MA, Guo Y, Shyr Y, Davé UP
(2014) Exp Hematol 42: 581-93.e5
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, CD4 Antigens, Epigenesis, Genetic, Humans, In Situ Hybridization, Fluorescence, LIM Domain Proteins, Leukemia, T-Cell, Mice, Mice, Transgenic, Proto-Oncogene Proteins
Added June 26, 2014
0 Communities
2 Members
0 Resources
11 MeSH Terms
LIM domain only-2 (LMO2) induces T-cell leukemia by two distinct pathways.
Smith S, Tripathi R, Goodings C, Cleveland S, Mathias E, Hardaway JA, Elliott N, Yi Y, Chen X, Downing J, Mullighan C, Swing DA, Tessarollo L, Li L, Love P, Jenkins NA, Copeland NG, Thompson MA, Du Y, Davé UP
(2014) PLoS One 9: e85883
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Base Sequence, Basic Helix-Loop-Helix Transcription Factors, CD2 Antigens, Carcinogenesis, Cell Line, Tumor, E-Box Elements, Gene Expression Regulation, Leukemic, Homeodomain Proteins, Humans, LIM Domain Proteins, Leukemia, T-Cell, Mice, Mice, Transgenic, Molecular Sequence Data, Neoplasm Proteins, Oncogenes, Penetrance, Precursor T-Cell Lymphoblastic Leukemia-Lymphoma, Promoter Regions, Genetic, Protein Binding, Proto-Oncogene Proteins, Signal Transduction, Transcription Factors, Transcription, Genetic, Up-Regulation
Added March 5, 2014
0 Communities
2 Members
0 Resources
27 MeSH Terms
Lmo2 induces hematopoietic stem cell-like features in T-cell progenitor cells prior to leukemia.
Cleveland SM, Smith S, Tripathi R, Mathias EM, Goodings C, Elliott N, Peng D, El-Rifai W, Yi D, Chen X, Li L, Mullighan C, Downing JR, Love P, Davé UP
(2013) Stem Cells 31: 882-94
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Cell Differentiation, Cell Lineage, Gene Expression, Hematopoietic Stem Cells, LIM Domain Proteins, Leukemia, T-Cell, Mice, Mice, Inbred C57BL, Mice, Transgenic, Precursor Cells, T-Lymphoid
Added September 3, 2013
0 Communities
4 Members
0 Resources
12 MeSH Terms
Islet α-, β-, and δ-cell development is controlled by the Ldb1 coregulator, acting primarily with the islet-1 transcription factor.
Hunter CS, Dixit S, Cohen T, Ediger B, Wilcox C, Ferreira M, Westphal H, Stein R, May CL
(2013) Diabetes 62: 875-86
MeSH Terms: Animals, Cell Nucleus, DNA-Binding Proteins, Female, Gene Expression Regulation, Glucagon-Secreting Cells, Insulin-Secreting Cells, Islets of Langerhans, LIM Domain Proteins, LIM-Homeodomain Proteins, Male, Mice, Mice, Knockout, Mice, Mutant Strains, Mice, Transgenic, Organ Specificity, Organogenesis, Protein Isoforms, RNA, Messenger, Somatostatin-Secreting Cells, Transcription Factors
Added December 5, 2013
1 Communities
1 Members
0 Resources
21 MeSH Terms