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Results: 1 to 8 of 8

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Combined vitamin C and E deficiency induces motor defects in gulo(-/-)/SVCT2(+/-) mice.
Pierce MR, Diasio DL, Rodrigues LM, Harrison FE, May JM
(2013) Nutr Neurosci 16: 160-73
MeSH Terms: Animals, Antioxidants, Ascorbic Acid, Biomarkers, Brain, Dietary Supplements, Disease Models, Animal, F2-Isoprostanes, Female, L-Gulonolactone Oxidase, Liver, Male, Malondialdehyde, Mice, Mice, Knockout, Oxidative Stress, Psychomotor Performance, Vitamin D Deficiency, Vitamin E, Vitamin E Deficiency
Added May 27, 2014
0 Communities
2 Members
0 Resources
20 MeSH Terms
Behavioral and monoamine changes following severe vitamin C deficiency.
Ward MS, Lamb J, May JM, Harrison FE
(2013) J Neurochem 124: 363-75
MeSH Terms: Animals, Ascorbic Acid, Ascorbic Acid Deficiency, Behavior, Animal, Biogenic Monoamines, Disease Models, Animal, Female, L-Gulonolactone Oxidase, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Severity of Illness Index
Added December 10, 2013
0 Communities
2 Members
0 Resources
13 MeSH Terms
Low ascorbic acid and increased oxidative stress in gulo(-/-) mice during development.
Harrison FE, Meredith ME, Dawes SM, Saskowski JL, May JM
(2010) Brain Res 1349: 143-52
MeSH Terms: Animals, Animals, Newborn, Ascorbic Acid, Brain, Embryo, Mammalian, F2-Isoprostanes, Female, Gene Expression Regulation, Developmental, Glial Fibrillary Acidic Protein, Glutathione, L-Gulonolactone Oxidase, Liver, Male, Malondialdehyde, Mice, Mice, Knockout, Oxidative Stress, Protein Carbonylation
Added December 10, 2013
0 Communities
2 Members
0 Resources
18 MeSH Terms
Vitamin C distribution and retention in the mouse brain.
Harrison FE, Green RJ, Dawes SM, May JM
(2010) Brain Res 1348: 181-6
MeSH Terms: Animals, Ascorbic Acid, Ascorbic Acid Deficiency, Brain, Disease Models, Animal, L-Gulonolactone Oxidase, Malondialdehyde, Mice, Mice, Inbred C57BL, Mice, Knockout, Oxidative Stress, Statistics, Nonparametric, Tissue Distribution
Added December 10, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms
Combined vitamin C and vitamin E deficiency worsens early atherosclerosis in apolipoprotein E-deficient mice.
Babaev VR, Li L, Shah S, Fazio S, Linton MF, May JM
(2010) Arterioscler Thromb Vasc Biol 30: 1751-7
MeSH Terms: Animals, Aortic Diseases, Apolipoproteins E, Ascorbic Acid, Ascorbic Acid Deficiency, Atherosclerosis, Brain, Dietary Supplements, Disease Models, Animal, Disease Progression, Female, L-Gulonolactone Oxidase, Lipid Peroxidation, Liver, Macrophages, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Myocardium, Organic Anion Transporters, Sodium-Dependent, Oxidative Stress, Severity of Illness Index, Sex Factors, Sodium-Coupled Vitamin C Transporters, Symporters, Time Factors, Vitamin E, Vitamin E Deficiency, Vitamins
Added December 10, 2013
0 Communities
2 Members
0 Resources
30 MeSH Terms
Vitamin C deficiency increases basal exploratory activity but decreases scopolamine-induced activity in APP/PSEN1 transgenic mice.
Harrison FE, May JM, McDonald MP
(2010) Pharmacol Biochem Behav 94: 543-52
MeSH Terms: Amyloid, Amyloid beta-Protein Precursor, Animals, Ascorbic Acid, Ascorbic Acid Deficiency, Brain, Exploratory Behavior, Female, L-Gulonolactone Oxidase, Lipid Peroxidation, Male, Maze Learning, Mice, Mice, Transgenic, Oxidative Stress, Presenilin-1, Survival Rate
Added December 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Elevated oxidative stress and sensorimotor deficits but normal cognition in mice that cannot synthesize ascorbic acid.
Harrison FE, Yu SS, Van Den Bossche KL, Li L, May JM, McDonald MP
(2008) J Neurochem 106: 1198-208
MeSH Terms: Animals, Ascorbic Acid, Ascorbic Acid Deficiency, Cognition, Female, L-Gulonolactone Oxidase, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Motor Activity, Motor Skills Disorders, Oxidative Stress, Psychomotor Performance
Added December 10, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms
Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation.
Gaut JP, Belaaouaj A, Byun J, Roberts LJ, Maeda N, Frei B, Heinecke JW
(2006) Free Radic Biol Med 40: 1494-501
MeSH Terms: Amino Acids, Animals, Antioxidants, Ascorbic Acid, Inflammation, Klebsiella Infections, Klebsiella pneumoniae, L-Gulonolactone Oxidase, Lipid Peroxidation, Mice, Mice, Knockout, Oxidation-Reduction, Sepsis
Added December 10, 2013
0 Communities
1 Members
0 Resources
13 MeSH Terms