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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 12

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Non-canonical roles for metabolic enzymes and intermediates in malignant progression and metastasis.
Williams D, Fingleton B
(2019) Clin Exp Metastasis 36: 211-224
MeSH Terms: ATP Citrate (pro-S)-Lyase, Disease Progression, Energy Metabolism, Fatty Acids, Glucose, Glucose-6-Phosphate Isomerase, Glutaminase, Glutamine, Humans, Isocitrate Dehydrogenase, Neoplasm Metastasis, Neoplasms
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Comprehensive and Integrative Genomic Characterization of Hepatocellular Carcinoma.
Cancer Genome Atlas Research Network. Electronic address: wheeler@bcm.edu, Cancer Genome Atlas Research Network
(2017) Cell 169: 1327-1341.e23
MeSH Terms: Carcinoma, Hepatocellular, DNA Methylation, Genomics, Humans, Isocitrate Dehydrogenase, Liver Neoplasms, MicroRNAs, Mutation
Added October 30, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Mutant IDH1 and seizures in patients with glioma.
Chen H, Judkins J, Thomas C, Wu M, Khoury L, Benjamin CG, Pacione D, Golfinos JG, Kumthekar P, Ghamsari F, Chen L, Lein P, Chetkovich DM, Snuderl M, Horbinski C
(2017) Neurology 88: 1805-1813
MeSH Terms: Action Potentials, Animals, Brain Neoplasms, Cells, Cultured, Cerebral Cortex, Chromosome Deletion, Chromosomes, Human, Pair 1, Female, Glioma, Glutarates, Humans, Isocitrate Dehydrogenase, Male, Middle Aged, Mutation, Neoplasm Grading, Neurons, Rats, Sprague-Dawley, Retrospective Studies, Seizures
Added April 2, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Integrative Genomic Analysis of Cholangiocarcinoma Identifies Distinct IDH-Mutant Molecular Profiles.
Farshidfar F, Zheng S, Gingras MC, Newton Y, Shih J, Robertson AG, Hinoue T, Hoadley KA, Gibb EA, Roszik J, Covington KR, Wu CC, Shinbrot E, Stransky N, Hegde A, Yang JD, Reznik E, Sadeghi S, Pedamallu CS, Ojesina AI, Hess JM, Auman JT, Rhie SK, Bowlby R, Borad MJ, Cancer Genome Atlas Network, Zhu AX, Stuart JM, Sander C, Akbani R, Cherniack AD, Deshpande V, Mounajjed T, Foo WC, Torbenson MS, Kleiner DE, Laird PW, Wheeler DA, McRee AJ, Bathe OF, Andersen JB, Bardeesy N, Roberts LR, Kwong LN
(2017) Cell Rep 18: 2780-2794
MeSH Terms: Adult, Aged, Aged, 80 and over, Bile Duct Neoplasms, Cholangiocarcinoma, Chromatin, DNA Methylation, DNA-Binding Proteins, Female, Gene Expression Regulation, Neoplastic, Genomics, Humans, Isocitrate Dehydrogenase, Liver, Liver Neoplasms, Male, Middle Aged, Mitochondria, Mutation, Nuclear Proteins, Pancreatic Neoplasms, Promoter Regions, Genetic, RNA, Long Noncoding, RNA, Messenger, Transcription Factors
Added October 30, 2019
0 Communities
1 Members
0 Resources
25 MeSH Terms
Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma.
Ceccarelli M, Barthel FP, Malta TM, Sabedot TS, Salama SR, Murray BA, Morozova O, Newton Y, Radenbaugh A, Pagnotta SM, Anjum S, Wang J, Manyam G, Zoppoli P, Ling S, Rao AA, Grifford M, Cherniack AD, Zhang H, Poisson L, Carlotti CG, Tirapelli DP, Rao A, Mikkelsen T, Lau CC, Yung WK, Rabadan R, Huse J, Brat DJ, Lehman NL, Barnholtz-Sloan JS, Zheng S, Hess K, Rao G, Meyerson M, Beroukhim R, Cooper L, Akbani R, Wrensch M, Haussler D, Aldape KD, Laird PW, Gutmann DH, TCGA Research Network, Noushmehr H, Iavarone A, Verhaak RG
(2016) Cell 164: 550-63
MeSH Terms: Adult, Brain Neoplasms, Cell Proliferation, Cluster Analysis, DNA Helicases, DNA Methylation, Epigenesis, Genetic, Glioma, Humans, Isocitrate Dehydrogenase, Middle Aged, Mutation, Nuclear Proteins, Promoter Regions, Genetic, Signal Transduction, Telomerase, Telomere, Transcriptome, X-linked Nuclear Protein
Added August 8, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms
D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice.
Akbay EA, Moslehi J, Christensen CL, Saha S, Tchaicha JH, Ramkissoon SH, Stewart KM, Carretero J, Kikuchi E, Zhang H, Cohoon TJ, Murray S, Liu W, Uno K, Fisch S, Jones K, Gurumurthy S, Gliser C, Choe S, Keenan M, Son J, Stanley I, Losman JA, Padera R, Bronson RT, Asara JM, Abdel-Wahab O, Amrein PC, Fathi AT, Danial NN, Kimmelman AC, Kung AL, Ligon KL, Yen KE, Kaelin WG, Bardeesy N, Wong KK
(2014) Genes Dev 28: 479-90
MeSH Terms: Animals, Cardiomyopathies, Cell Line, Gene Expression Profiling, Gene Expression Regulation, Developmental, Glutarates, Heart, Humans, Isocitrate Dehydrogenase, Mice, Mice, Inbred BALB C, Mice, Nude, Mutation, Neurodegenerative Diseases
Added March 4, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Primary orthotopic glioma xenografts recapitulate infiltrative growth and isocitrate dehydrogenase I mutation.
Valadez JG, Sarangi A, Lundberg CJ, Cooper MK
(2014) J Vis Exp : e50865
MeSH Terms: Animals, Brain Neoplasms, Glioma, Heterografts, Humans, Isocitrate Dehydrogenase, Mice, Mutation, Neoplasm Transplantation, Transplantation, Heterologous
Added March 21, 2014
0 Communities
1 Members
0 Resources
10 MeSH Terms
Re-evaluation of nondiagnostic biopsies of suspected low-grade glioma using isocitrate dehydrogenase 1 mutation immunohistochemistry.
Anderson MD, Abel TW, Moots PL
(2013) Neuro Oncol 15: 811-3
MeSH Terms: Adult, Biopsy, Brain Neoplasms, Evaluation Studies as Topic, False Positive Reactions, Glioma, Humans, Immunoenzyme Techniques, Isocitrate Dehydrogenase, Middle Aged, Mutant Proteins, Mutation, Neoplasm Grading
Added March 7, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms
Alteration of isocitrate dehydrogenase following acute ischemic injury as a means to improve cellular energetic status in neuroadaptation.
Grelli KN, Palubinsky AM, Kale AC, Lizama-Manibusan BN, Stankowski JN, Milne GL, Singer R, McLaughlin B
(2013) CNS Neurol Disord Drug Targets 12: 849-60
MeSH Terms: Acute Disease, Adaptation, Physiological, Animals, Brain Ischemia, Cell Line, Transformed, Cells, Cultured, Cerebral Cortex, Energy Metabolism, Isocitrate Dehydrogenase, Mice, Neurons, Rats, Rats, Sprague-Dawley
Added March 26, 2014
1 Communities
2 Members
0 Resources
13 MeSH Terms
Identification of Hedgehog pathway responsive glioblastomas by isocitrate dehydrogenase mutation.
Gerardo Valadez J, Grover VK, Carter MD, Calcutt MW, Abiria SA, Lundberg CJ, Williams TV, Cooper MK
(2013) Cancer Lett 328: 297-306
MeSH Terms: AC133 Antigen, Animals, Antigens, CD, Cell Line, Tumor, Gene Expression Profiling, Gene Expression Regulation, Neoplastic, Glioblastoma, Glycoproteins, Hedgehog Proteins, Humans, Isocitrate Dehydrogenase, Mice, Mutation, Neoplasm Grading, Patched Receptors, Patched-1 Receptor, Peptides, Receptors, Cell Surface, Signal Transduction, Transplantation, Heterologous
Added March 7, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms