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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 25

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Quaternary epitopes of α345(IV) collagen initiate Alport post-transplant anti-GBM nephritis.
Olaru F, Luo W, Wang XP, Ge L, Hertz JM, Kashtan CE, Sado Y, Segal Y, Hudson BG, Borza DB
(2013) J Am Soc Nephrol 24: 889-95
MeSH Terms: Animals, Anti-Glomerular Basement Membrane Disease, Autoantigens, Basement Membrane, Cattle, Collagen Type IV, Epitope Mapping, Haplorhini, Humans, Immunoglobulin G, Isoantibodies, Kidney Glomerulus, Kidney Transplantation, Mice, Mice, Transgenic, Nephritis, Hereditary, Postoperative Complications, Protein Interaction Domains and Motifs, Protein Structure, Quaternary, Transplantation, Homologous
Added August 21, 2013
1 Communities
2 Members
0 Resources
20 MeSH Terms
Alport alloantibodies but not Goodpasture autoantibodies induce murine glomerulonephritis: protection by quinary crosslinks locking cryptic α3(IV) collagen autoepitopes in vivo.
Luo W, Wang XP, Kashtan CE, Borza DB
(2010) J Immunol 185: 3520-8
MeSH Terms: Animals, Anti-Glomerular Basement Membrane Disease, Autoantibodies, Autoantigens, Binding Sites, Antibody, Collagen Type IV, Cross Reactions, Epitopes, Glomerulonephritis, Humans, Isoantibodies, Mice, Mice, Inbred C57BL, Mice, Knockout, Nephritis, Hereditary, Protein Structure, Tertiary
Added August 21, 2013
0 Communities
1 Members
0 Resources
16 MeSH Terms
Molecular architecture of the Goodpasture autoantigen in anti-GBM nephritis.
Pedchenko V, Bondar O, Fogo AB, Vanacore R, Voziyan P, Kitching AR, Wieslander J, Kashtan C, Borza DB, Neilson EG, Wilson CB, Hudson BG
(2010) N Engl J Med 363: 343-54
MeSH Terms: Adult, Aged, Aged, 80 and over, Anti-Glomerular Basement Membrane Disease, Antibodies, Autoantibodies, Autoantigens, Binding Sites, Antibody, Collagen Type IV, Enzyme-Linked Immunosorbent Assay, Epitope Mapping, Epitopes, Female, Glomerular Basement Membrane, Humans, Isoantibodies, Kidney Glomerulus, Kidney Transplantation, Male, Middle Aged, Nephritis, Nephritis, Hereditary, Postoperative Complications, Protein Conformation, Protein Isoforms, Retrospective Studies, Young Adult
Added December 10, 2013
1 Communities
6 Members
1 Resources
27 MeSH Terms
Long-term control of alloreactive B cell responses by the suppression of T cell help.
Li Y, Ma L, Yin D, Shen J, Chong AS
(2008) J Immunol 180: 6077-84
MeSH Terms: Animals, B-Lymphocytes, CD40 Ligand, Graft Rejection, Heart Transplantation, Isoantibodies, Lymphocyte Depletion, Mice, Mice, Inbred BALB C, Mice, Knockout, Receptors, Antigen, B-Cell, T-Lymphocytes, Time Factors, Transplantation Tolerance, Transplantation, Homologous
Added December 10, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms
Autoepitopes and alloepitopes of type IV collagen: role in the molecular pathogenesis of anti-GBM antibody glomerulonephritis.
Borza DB
(2007) Nephron Exp Nephrol 106: e37-43
MeSH Terms: Anti-Glomerular Basement Membrane Disease, Autoantibodies, Collagen Type IV, Epitope Mapping, Glomerular Basement Membrane, Glomerulonephritis, Humans, Immunity, Innate, Isoantibodies, Models, Immunological
Added August 21, 2013
0 Communities
1 Members
0 Resources
10 MeSH Terms
The alloantigenic sites of alpha3alpha4alpha5(IV) collagen: pathogenic X-linked alport alloantibodies target two accessible conformational epitopes in the alpha5NC1 domain.
Kang JS, Kashtan CE, Turner AN, Heidet L, Hudson BG, Borza DB
(2007) J Biol Chem 282: 10670-7
MeSH Terms: Adult, Collagen Type IV, Epitope Mapping, Epitopes, B-Lymphocyte, Humans, Isoantibodies, Isoantigens, Kidney Transplantation, Male, Nephritis, Nephritis, Hereditary, Protein Structure, Tertiary, Transplantation Chimera, Transplantation, Homologous
Added December 10, 2013
1 Communities
2 Members
0 Resources
14 MeSH Terms
Distinct epitopes for anti-glomerular basement membrane alport alloantibodies and goodpasture autoantibodies within the noncollagenous domain of alpha3(IV) collagen: a janus-faced antigen.
Wang XP, Fogo AB, Colon S, Giannico G, Abul-Ezz SR, Miner JH, Borza DB
(2005) J Am Soc Nephrol 16: 3563-71
MeSH Terms: Adult, Anti-Glomerular Basement Membrane Disease, Antibodies, Autoantibodies, Biopsy, Needle, Collagen, Collagen Type IV, Disease Progression, Enzyme-Linked Immunosorbent Assay, Epitopes, Fatal Outcome, Female, Graft Rejection, Humans, Immunohistochemistry, Isoantibodies, Kidney Failure, Chronic, Kidney Transplantation, Nephritis, Hereditary, Risk Assessment, Transplantation Immunology
Added August 21, 2013
1 Communities
3 Members
0 Resources
21 MeSH Terms
C4d deposition in cardiac allografts correlates with alloantibody.
Smith RN, Brousaides N, Grazette L, Saidman S, Semigran M, Disalvo T, Madsen J, Dec GW, Perez-Atayde AR, Collins AB
(2005) J Heart Lung Transplant 24: 1202-10
MeSH Terms: Biomarkers, Biopsy, Capillaries, Coloring Agents, Complement C4b, Coronary Vessels, Fluorescent Antibody Technique, Graft Rejection, Heart Transplantation, Humans, Immunosuppressive Agents, Isoantibodies, Muromonab-CD3, Myocardial Ischemia, Myocardium, Peptide Fragments
Added May 27, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
The molecular basis of Goodpasture and Alport syndromes: beacons for the discovery of the collagen IV family.
Hudson BG
(2004) J Am Soc Nephrol 15: 2514-27
MeSH Terms: Amino Acid Sequence, Animals, Anti-Glomerular Basement Membrane Disease, Collagen Type IV, Female, Humans, Integrin alpha1, Integrin alpha2, Integrin alpha3, Isoantibodies, Isoantigens, Male, Molecular Biology, Mutation, Nephritis, Hereditary, Prognosis, Promoter Regions, Genetic, Severity of Illness Index
Added December 10, 2013
1 Communities
1 Members
0 Resources
18 MeSH Terms
Local actions of endogenous angiotensin II in injured glomeruli.
Ma J, Matsusaka T, Yang H, Kawachi H, Shimizu F, Isaka Y, Imai E, Kon V, Ichikawa I
(2004) J Am Soc Nephrol 15: 1268-76
MeSH Terms: Angiotensin II, Angiotensin II Type 1 Receptor Blockers, Animals, Antihypertensive Agents, Cell Division, DNA, Antisense, Genetic Therapy, Glomerular Mesangium, Glomerulonephritis, Isoantibodies, Kidney Glomerulus, Losartan, Male, Rats, Rats, Wistar, Receptor, Angiotensin, Type 1, Receptor, Angiotensin, Type 2, Transfection
Added January 25, 2012
0 Communities
2 Members
0 Resources
18 MeSH Terms