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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 60

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Tuft Cells Inhibit Pancreatic Tumorigenesis in Mice by Producing Prostaglandin D.
DelGiorno KE, Chung CY, Vavinskaya V, Maurer HC, Novak SW, Lytle NK, Ma Z, Giraddi RR, Wang D, Fang L, Naeem RF, Andrade LR, Ali WH, Tseng H, Tsui C, Gubbala VB, Ridinger-Saison M, Ohmoto M, Erikson GA, O'Connor C, Shokhirev MN, Hah N, Urade Y, Matsumoto I, Kaech SM, Singh PK, Manor U, Olive KP, Wahl GM
(2020) Gastroenterology 159: 1866-1881.e8
MeSH Terms: Animals, Carcinoma, Pancreatic Ductal, Cell Transformation, Neoplastic, Ceruletide, Disease Models, Animal, Energy Metabolism, Fibrosis, Humans, Interleukins, Intramolecular Oxidoreductases, Mice, Transgenic, Mutation, Octamer Transcription Factors, Pancreas, Pancreatic Neoplasms, Pancreatitis, Prostaglandin D2, Proto-Oncogene Proteins p21(ras), Time Factors, Transcription Factors
Added March 13, 2021
0 Communities
1 Members
0 Resources
20 MeSH Terms
Nonsteroidal Anti-inflammatory Drug Interaction with Prostacyclin Synthase Protects from Miscarriage.
Velez Edwards DR, Edwards TL, Bray MJ, Torstenson E, Jones S, Shrubsole MJ, Muff HJ, Hartmann KE
(2017) Sci Rep 7: 9874
MeSH Terms: Abortion, Spontaneous, Adult, Alleles, Anti-Inflammatory Agents, Non-Steroidal, Cytochrome P-450 Enzyme System, Disease Susceptibility, Female, Genotype, Humans, Intramolecular Oxidoreductases, Odds Ratio, Polymorphism, Single Nucleotide, Pregnancy, Risk Factors
Added February 21, 2019
0 Communities
1 Members
0 Resources
14 MeSH Terms
Oxicams, a class of nonsteroidal anti-inflammatory drugs and beyond.
Xu S, Rouzer CA, Marnett LJ
(2014) IUBMB Life 66: 803-11
MeSH Terms: Anti-Inflammatory Agents, Non-Steroidal, Humans, Inflammation, Intramolecular Oxidoreductases, Meloxicam, Piroxicam, Prostaglandin-E Synthases, Thiazines, Thiazoles
Added February 22, 2016
0 Communities
2 Members
0 Resources
9 MeSH Terms
Functional prostacyclin synthase promoter polymorphisms. Impact in pulmonary arterial hypertension.
Stearman RS, Cornelius AR, Lu X, Conklin DS, Del Rosario MJ, Lowe AM, Elos MT, Fettig LM, Wong RE, Hara N, Cogan JD, Phillips JA, Taylor MR, Graham BB, Tuder RM, Loyd JE, Geraci MW
(2014) Am J Respir Crit Care Med 189: 1110-20
MeSH Terms: Bone Morphogenetic Protein Receptors, Type II, Case-Control Studies, Cytochrome P-450 Enzyme System, Disease Progression, Familial Primary Pulmonary Hypertension, Female, Haplotypes, Heterozygote, Humans, Hypertension, Pulmonary, Intramolecular Oxidoreductases, Male, Mutation, Polymerase Chain Reaction, Polymorphism, Genetic
Added March 20, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Reduced T cell-dependent humoral immune response in microsomal prostaglandin E synthase-1 null mice is mediated by nonhematopoietic cells.
Kojima F, Frolov A, Matnani R, Woodward JG, Crofford LJ
(2013) J Immunol 191: 4979-88
MeSH Terms: Animals, Arthritis, Experimental, Bone Marrow Transplantation, Cells, Cultured, Collagen, Female, Immunity, Humoral, Immunoglobulin G, Immunoglobulin M, Interferon-gamma, Interleukin-17, Interleukin-2, Interleukin-4, Intramolecular Oxidoreductases, Male, Mice, Mice, Inbred DBA, Mice, Knockout, Prostaglandin-E Synthases, T-Lymphocytes
Added January 21, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Anti-inflammatory properties of prostaglandin E2: deletion of microsomal prostaglandin E synthase-1 exacerbates non-immune inflammatory arthritis in mice.
Frolov A, Yang L, Dong H, Hammock BD, Crofford LJ
(2013) Prostaglandins Leukot Essent Fatty Acids 89: 351-8
MeSH Terms: Animals, Arthritis, Experimental, Autoantibodies, Chromatography, Liquid, Collagen Type II, Dinoprostone, Female, Gene Deletion, Inflammation, Intramolecular Oxidoreductases, Joints, Lipid Metabolism, Macrophages, Male, Mice, Neutrophil Infiltration, Neutrophils, Prostaglandin-E Synthases, Severity of Illness Index, Tandem Mass Spectrometry
Added January 21, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Nrf2 is essential for the expression of lipocalin-prostaglandin D synthase induced by prostaglandin D2.
Kim KH, Sadikot RT, Xiao L, Christman JW, Freeman ML, Chan JY, Oh YK, Blackwell TS, Joo M
(2013) Free Radic Biol Med 65: 1134-1142
MeSH Terms: Amino Acid Sequence, Animals, Base Sequence, Binding Sites, Cell Line, Cyclooxygenase 2, Intramolecular Oxidoreductases, Lipocalins, Lipopolysaccharides, Lung, Macrophages, Mice, Mice, Inbred C57BL, Mice, Knockout, NF-E2-Related Factor 2, Neutrophil Infiltration, Neutrophils, Pneumonia, Promoter Regions, Genetic, Prostaglandin D2, Protein Binding, RNA Interference, RNA, Small Interfering, Sequence Analysis, DNA, Toll-Like Receptor 4
Added March 7, 2014
1 Communities
2 Members
0 Resources
25 MeSH Terms
Steric analysis of epoxyalcohol and trihydroxy derivatives of 9-hydroperoxy-linoleic acid from hematin and enzymatic synthesis.
Thomas CP, Boeglin WE, Garcia-Diaz Y, O'Donnell VB, Brash AR
(2013) Chem Phys Lipids 167-168: 21-32
MeSH Terms: Beta vulgaris, Chromatography, High Pressure Liquid, Epoxide Hydrolases, Epoxy Compounds, Gas Chromatography-Mass Spectrometry, Hemin, Hydrolysis, Intramolecular Oxidoreductases, Isomerism, Linoleic Acid, Magnetic Resonance Spectroscopy, Oleic Acids, Propanols, Stereoisomerism
Added March 7, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Prostaglandin E2 deficiency uncovers a dominant role for thromboxane A2 in house dust mite-induced allergic pulmonary inflammation.
Liu T, Laidlaw TM, Feng C, Xing W, Shen S, Milne GL, Boyce JA
(2012) Proc Natl Acad Sci U S A 109: 12692-7
MeSH Terms: Allergens, Animals, Antigens, Dermatophagoides, Asthma, Dinoprostone, Intercellular Adhesion Molecule-1, Intramolecular Oxidoreductases, Male, Mice, Mice, Knockout, Pneumonia, Prostaglandin-E Synthases, Pulmonary Eosinophilia, Receptors, Prostaglandin E, EP1 Subtype, Receptors, Prostaglandin E, EP2 Subtype, Receptors, Thromboxane, Signal Transduction, Thromboxane A2, Up-Regulation
Added March 26, 2014
1 Communities
1 Members
0 Resources
19 MeSH Terms
Cytochrome P450-type hydroxylation and epoxidation in a tyrosine-liganded hemoprotein, catalase-related allene oxide synthase.
Boeglin WE, Brash AR
(2012) J Biol Chem 287: 24139-47
MeSH Terms: Catalase, Chromatography, High Pressure Liquid, Cytochrome P-450 Enzyme System, Gas Chromatography-Mass Spectrometry, Hemeproteins, Hydroxylation, Intramolecular Oxidoreductases, Iodobenzenes, Linoleic Acids, Magnetic Resonance Spectroscopy
Added January 21, 2015
0 Communities
1 Members
0 Resources
10 MeSH Terms