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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 104

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PARP9 and PARP14 cross-regulate macrophage activation via STAT1 ADP-ribosylation.
Iwata H, Goettsch C, Sharma A, Ricchiuto P, Goh WW, Halu A, Yamada I, Yoshida H, Hara T, Wei M, Inoue N, Fukuda D, Mojcher A, Mattson PC, Barabási AL, Boothby M, Aikawa E, Singh SA, Aikawa M
(2016) Nat Commun 7: 12849
MeSH Terms: ADP-Ribosylation, Animals, Apoptosis, Atherosclerosis, Cell Survival, Coronary Artery Disease, Female, Humans, Inflammation, Interferon-gamma, Interleukin-4, Lipopolysaccharide Receptors, Macrophage Activation, Male, Mice, Mice, Inbred C57BL, Neoplasm Proteins, Phosphorylation, Plaque, Atherosclerotic, Poly(ADP-ribose) Polymerases, RAW 264.7 Cells, RNA Interference, Ribose, STAT1 Transcription Factor, THP-1 Cells
Added March 14, 2018
0 Communities
1 Members
0 Resources
25 MeSH Terms
IL-4/IL-13-mediated polarization of renal macrophages/dendritic cells to an M2a phenotype is essential for recovery from acute kidney injury.
Zhang MZ, Wang X, Wang Y, Niu A, Wang S, Zou C, Harris RC
(2017) Kidney Int 91: 375-386
MeSH Terms: Acute Kidney Injury, Animals, Cell Plasticity, Dendritic Cells, Diphtheria Toxin, Disease Models, Animal, Fibrosis, Genotype, Heparin-binding EGF-like Growth Factor, Interleukin-13, Interleukin-4, Janus Kinase 3, Kidney, Macrophages, Male, Mice, 129 Strain, Mice, Inbred BALB C, Mice, Knockout, Phenotype, Recovery of Function, Reperfusion Injury, STAT6 Transcription Factor, Signal Transduction, Time Factors
Added April 26, 2017
1 Communities
1 Members
0 Resources
24 MeSH Terms
Activation of Epidermal Growth Factor Receptor in Macrophages Mediates Feedback Inhibition of M2 Polarization and Gastrointestinal Tumor Cell Growth.
Zhao G, Liu L, Peek RM, Hao X, Polk DB, Li H, Yan F
(2016) J Biol Chem 291: 20462-72
MeSH Terms: Animals, Cell Line, Tumor, ErbB Receptors, Gastrointestinal Neoplasms, Gene Expression Regulation, Neoplastic, Heparin-binding EGF-like Growth Factor, Humans, Interleukin-4, Macrophages, Peritoneal, Mice, Mice, Knockout, RAW 264.7 Cells, Transcriptional Activation
Added April 6, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
Class-switched anti-insulin antibodies originate from unconventional antigen presentation in multiple lymphoid sites.
Wan X, Thomas JW, Unanue ER
(2016) J Exp Med 213: 967-78
MeSH Terms: Animals, Antigen Presentation, B-Lymphocytes, CD40 Antigens, Diabetes Mellitus, Type 1, Germinal Center, Immunoglobulin Class Switching, Insulin, Interleukin-4, Islets of Langerhans, Mice, Mice, Knockout, T-Lymphocytes
Added November 23, 2016
2 Communities
0 Members
0 Resources
13 MeSH Terms
Targeting IL4/IL4R for the treatment of epithelial cancer metastasis.
Bankaitis KV, Fingleton B
(2015) Clin Exp Metastasis 32: 847-56
MeSH Terms: Humans, Interleukin-4, Janus Kinase 1, Neoplasms, Glandular and Epithelial, Receptors, Interleukin-4, STAT6 Transcription Factor, Signal Transduction, Tumor Microenvironment
Added September 28, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
Trefoil factor 1 expression suppresses Helicobacter pylori-induced inflammation in gastric carcinogenesis.
Soutto M, Chen Z, Katsha AM, Romero-Gallo J, Krishna US, Piazuelo MB, Washington MK, Peek RM, Belkhiri A, El-Rifai WM
(2015) Cancer 121: 4348-58
MeSH Terms: Adenocarcinoma, Animals, Carcinogenesis, Chemokine CXCL5, Gastric Mucosa, Helicobacter Infections, Helicobacter pylori, Humans, I-kappa B Kinase, In Vitro Techniques, Inflammation, Interleukin-1beta, Mice, Mice, Knockout, Peptides, Phosphorylation, Real-Time Polymerase Chain Reaction, Receptors, Interleukin-4, Stomach, Stomach Neoplasms, Transcription Factor RelA, Trefoil Factor-1, Tumor Cells, Cultured, Tumor Necrosis Factor-alpha
Added September 28, 2015
0 Communities
3 Members
0 Resources
24 MeSH Terms
CCR2 deficiency leads to increased eosinophils, alternative macrophage activation, and type 2 cytokine expression in adipose tissue.
Bolus WR, Gutierrez DA, Kennedy AJ, Anderson-Baucum EK, Hasty AH
(2015) J Leukoc Biol 98: 467-77
MeSH Terms: Adipose Tissue, Animals, Cell Separation, Eosinophils, Flow Cytometry, Immunohistochemistry, Inflammation, Insulin Resistance, Interleukin-13, Interleukin-4, Interleukin-5, Macrophage Activation, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Obesity, Real-Time Polymerase Chain Reaction, Receptors, CCR2
Added September 28, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Bombesin Preserves Goblet Cell Resistin-Like Molecule β During Parenteral Nutrition but Not Other Goblet Cell Products.
Busch RA, Heneghan AF, Pierre JF, Neuman JC, Reimer CA, Wang X, Kimple ME, Kudsk KA
(2016) JPEN J Parenter Enteral Nutr 40: 1042-9
MeSH Terms: Animals, Bombesin, Goblet Cells, Hormones, Ectopic, Ileum, Immunity, Innate, Intercellular Signaling Peptides and Proteins, Interleukin-13, Interleukin-4, Male, Mice, Mice, Inbred ICR, Mucin-2, Paneth Cells, Parenteral Nutrition, Trefoil Factor-3
Added August 2, 2016
0 Communities
1 Members
0 Resources
16 MeSH Terms
IL4 receptor α mediates enhanced glucose and glutamine metabolism to support breast cancer growth.
Venmar KT, Kimmel DW, Cliffel DE, Fingleton B
(2015) Biochim Biophys Acta 1853: 1219-28
MeSH Terms: Animals, Breast Neoplasms, Cell Line, Tumor, Cell Proliferation, Female, Glucose, Glucose Transporter Type 1, Glutamine, Humans, Interleukin-4, Mammary Neoplasms, Animal, Membrane Transport Proteins, Mice, Receptors, Interleukin-4
Added September 28, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
TLR4 genotype and environmental LPS mediate RSV bronchiolitis through Th2 polarization.
Caballero MT, Serra ME, Acosta PL, Marzec J, Gibbons L, Salim M, Rodriguez A, Reynaldi A, Garcia A, Bado D, Buchholz UJ, Hijano DR, Coviello S, Newcomb D, Bellabarba M, Ferolla FM, Libster R, Berenstein A, Siniawaski S, Blumetti V, Echavarria M, Pinto L, Lawrence A, Ossorio MF, Grosman A, Mateu CG, Bayle C, Dericco A, Pellegrini M, Igarza I, Repetto HA, Grimaldi LA, Gudapati P, Polack NR, Althabe F, Shi M, Ferrero F, Bergel E, Stein RT, Peebles RS, Boothby M, Kleeberger SR, Polack FP
(2015) J Clin Invest 125: 571-82
MeSH Terms: Animals, Bronchiolitis, Viral, Disease Models, Animal, Environmental Exposure, Female, GATA3 Transcription Factor, Genotype, Humans, Infant, Infant, Newborn, Interferon-gamma, Interleukin-4, Lipopolysaccharides, Male, Mice, Respiratory Syncytial Virus Infections, Respiratory Syncytial Viruses, T-Box Domain Proteins, Th2 Cells, Toll-Like Receptor 4
Added January 20, 2015
0 Communities
2 Members
0 Resources
20 MeSH Terms