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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 149

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HLA-Restriction of Human Treg Cells Is Not Required for Therapeutic Efficacy of Low-Dose IL-2 in Humanized Mice.
Tyagi RK, Jacobse J, Li J, Allaman MM, Otipoby KL, Sampson ER, Wilson KT, Goettel JA
(2021) Front Immunol 12: 630204
MeSH Terms: Animals, HLA Antigens, Humans, Inflammatory Bowel Diseases, Interleukin-2, Mice, Mice, Inbred NOD, T-Lymphocyte Subsets, T-Lymphocytes, Regulatory, Trinitrobenzenesulfonic Acid
Added March 17, 2021
0 Communities
1 Members
0 Resources
10 MeSH Terms
Treg sensitivity to FasL and relative IL-2 deprivation drive idiopathic aplastic anemia immune dysfunction.
Lim SP, Costantini B, Mian SA, Perez Abellan P, Gandhi S, Martinez Llordella M, Lozano JJ, Antunes Dos Reis R, Povoleri GAM, Mourikis TP, Abarrategi A, Ariza-McNaughton L, Heck S, Irish JM, Lombardi G, Marsh JCW, Bonnet D, Kordasti S, Mufti GJ
(2020) Blood 136: 885-897
MeSH Terms: Anemia, Aplastic, Animals, Apoptosis, Cells, Cultured, Fas Ligand Protein, Female, Humans, Immune System Diseases, Immune Tolerance, Interleukin-2, Male, Mice, Mice, Inbred NOD, Mice, SCID, Mice, Transgenic, T-Lymphocytes, Regulatory
Added June 8, 2020
1 Communities
1 Members
0 Resources
16 MeSH Terms
VacA Targets Myeloid Cells in the Gastric Lamina Propria To Promote Peripherally Induced Regulatory T-Cell Differentiation and Persistent Infection.
Altobelli A, Bauer M, Velez K, Cover TL, M├╝ller A
(2019) mBio 10:
MeSH Terms: Animals, Bacterial Proteins, Cell Differentiation, Dendritic Cells, Disease Models, Animal, Gastric Mucosa, Helicobacter Infections, Helicobacter pylori, Immune Evasion, Interleukin-10, Interleukin-23, Lung, Macrophages, Mice, Mucous Membrane, Myeloid Cells, T-Lymphocytes, Regulatory, Transforming Growth Factor beta
Added April 11, 2019
0 Communities
1 Members
0 Resources
18 MeSH Terms
Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients.
Rosen MJ, Karns R, Vallance JE, Bezold R, Waddell A, Collins MH, Haberman Y, Minar P, Baldassano RN, Hyams JS, Baker SS, Kellermayer R, Noe JD, Griffiths AM, Rosh JR, Crandall WV, Heyman MB, Mack DR, Kappelman MD, Markowitz J, Moulton DE, Leleiko NS, Walters TD, Kugathasan S, Wilson KT, Hogan SP, Denson LA
(2017) Gastroenterology 152: 1345-1357.e7
MeSH Terms: Adolescent, Area Under Curve, Case-Control Studies, Child, Colitis, Ulcerative, Colon, Crohn Disease, Female, Gene Expression, Humans, Immunity, Mucosal, Interleukin-13, Interleukin-13 Receptor alpha2 Subunit, Interleukin-17, Interleukin-23, Interleukin-5, Interleukins, Intestinal Mucosa, Male, Predictive Value of Tests, Prognosis, Prospective Studies, RNA, Messenger, ROC Curve, Rectum, Transcriptome, Up-Regulation
Added January 31, 2017
0 Communities
1 Members
0 Resources
27 MeSH Terms
Idiopathic subglottic stenosis is associated with activation of the inflammatory IL-17A/IL-23 axis.
Gelbard A, Katsantonis NG, Mizuta M, Newcomb D, Rotsinger J, Rousseau B, Daniero JJ, Edell ES, Ekbom DC, Kasperbauer JL, Hillel AT, Yang L, Garrett CG, Netterville JL, Wootten CT, Francis DO, Stratton C, Jenkins K, McGregor TL, Gaddy JA, Blackwell TS, Drake WP
(2016) Laryngoscope 126: E356-E361
MeSH Terms: Airway Obstruction, Case-Control Studies, Humans, Inflammation Mediators, Interleukin-17, Interleukin-23, Larynx, Signal Transduction, Trachea, Tracheal Stenosis
Added January 25, 2017
1 Communities
3 Members
0 Resources
10 MeSH Terms
Deep phenotyping of Tregs identifies an immune signature for idiopathic aplastic anemia and predicts response to treatment.
Kordasti S, Costantini B, Seidl T, Perez Abellan P, Martinez Llordella M, McLornan D, Diggins KE, Kulasekararaj A, Benfatto C, Feng X, Smith A, Mian SA, Melchiotti R, de Rinaldis E, Ellis R, Petrov N, Povoleri GA, Chung SS, Thomas NS, Farzaneh F, Irish JM, Heck S, Young NS, Marsh JC, Mufti GJ
(2016) Blood 128: 1193-205
MeSH Terms: Adult, Aged, Anemia, Aplastic, Female, Forkhead Transcription Factors, Humans, Immunologic Memory, Immunosuppression, Interleukin-2, Interleukin-7 Receptor alpha Subunit, Leukocyte Common Antigens, Male, Middle Aged, Receptors, CCR4, STAT5 Transcription Factor, T-Lymphocytes, Regulatory, fas Receptor
Added June 10, 2016
2 Communities
1 Members
0 Resources
17 MeSH Terms
Impact of NRAS mutations for patients with advanced melanoma treated with immune therapies.
Johnson DB, Lovly CM, Flavin M, Panageas KS, Ayers GD, Zhao Z, Iams WT, Colgan M, DeNoble S, Terry CR, Berry EG, Iafrate AJ, Sullivan RJ, Carvajal RD, Sosman JA
(2015) Cancer Immunol Res 3: 288-295
MeSH Terms: Antibodies, Monoclonal, Female, GTP Phosphohydrolases, Humans, Immunotherapy, Interleukin-2, Ipilimumab, Male, Melanoma, Membrane Proteins, Middle Aged, Mutation, Prognosis, Retrospective Studies
Added September 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.
Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW
(2015) J Clin Invest 125: 1111-23
MeSH Terms: Animals, Autoimmunity, Cells, Cultured, Forkhead Transcription Factors, Gene Expression Regulation, HEK293 Cells, Histone Deacetylases, Humans, Interleukin-2, Lymphocyte Activation, Male, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout, T-Lymphocytes, Regulatory
Added September 28, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
microRNA-mediated regulation of mTOR complex components facilitates discrimination between activation and anergy in CD4 T cells.
Marcais A, Blevins R, Graumann J, Feytout A, Dharmalingam G, Carroll T, Amado IF, Bruno L, Lee K, Walzer T, Mann M, Freitas AA, Boothby M, Fisher AG, Merkenschlager M
(2014) J Exp Med 211: 2281-95
MeSH Terms: Animals, Base Sequence, Binding Sites, CD4-Positive T-Lymphocytes, Clonal Anergy, Gene Expression Regulation, Humans, Interleukin-2, Lymphocyte Activation, Mice, Mice, Transgenic, MicroRNAs, Phosphorylation, Proto-Oncogene Proteins c-akt, Receptors, Antigen, T-Cell, Ribonuclease III, Signal Transduction, TOR Serine-Threonine Kinases
Added February 15, 2016
0 Communities
1 Members
0 Resources
18 MeSH Terms
DC isoketal-modified proteins activate T cells and promote hypertension.
Kirabo A, Fontana V, de Faria AP, Loperena R, Galindo CL, Wu J, Bikineyeva AT, Dikalov S, Xiao L, Chen W, Saleh MA, Trott DW, Itani HA, Vinh A, Amarnath V, Amarnath K, Guzik TJ, Bernstein KE, Shen XZ, Shyr Y, Chen SC, Mernaugh RL, Laffer CL, Elijovich F, Davies SS, Moreno H, Madhur MS, Roberts J, Harrison DG
(2014) J Clin Invest 124: 4642-56
MeSH Terms: Aged, Aldehydes, Angiotensin II, Animals, Antigen-Presenting Cells, B7-1 Antigen, B7-2 Antigen, Cell Proliferation, Cohort Studies, Dendritic Cells, Female, Gene Expression Regulation, Humans, Hypertension, Inflammation, Interleukin-17, Interleukin-1beta, Interleukin-23, Interleukin-6, Kidney, Lymphocyte Activation, Male, Mice, Mice, Transgenic, Middle Aged, Oxidative Stress, Oxygen, Superoxides, T-Lymphocytes
Added September 26, 2014
3 Communities
6 Members
0 Resources
29 MeSH Terms