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Anti-Tumor Effects after Adoptive Transfer of IL-12 Transposon-Modified Murine Splenocytes in the OT-I-Melanoma Mouse Model.
Galvan DL, O'Neil RT, Foster AE, Huye L, Bear A, Rooney CM, Wilson MH
(2015) PLoS One 10: e0140744
MeSH Terms: Adoptive Transfer, Animals, DNA Transposable Elements, HeLa Cells, Humans, Interleukin-12, Melanoma, Mice, Mice, Inbred NOD, Mice, SCID, Neoplasms, Experimental, Spleen, T-Lymphocytes
Added March 7, 2016
0 Communities
1 Members
0 Resources
13 MeSH Terms
Mycobacterium tuberculosis TlyA Protein Negatively Regulates T Helper (Th) 1 and Th17 Differentiation and Promotes Tuberculosis Pathogenesis.
Rahman MA, Sobia P, Dwivedi VP, Bhawsar A, Singh DK, Sharma P, Moodley P, Van Kaer L, Bishai WR, Das G
(2015) J Biol Chem 290: 14407-17
MeSH Terms: Animals, Bacterial Proteins, Host-Pathogen Interactions, Interleukin-10, Interleukin-12, Lung, Macrophages, Mice, Inbred BALB C, Mice, Inbred C57BL, Mutation, Mycobacterium tuberculosis, Th1 Cells, Th17 Cells, Tuberculosis, Virulence Factors
Added September 28, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Increased serum tumor necrosis factor α levels in patients with lenalidomide-induced hypothyroidism.
Iams WT, Hames ML, Tsai JP, Dahlman KB, Talbott MS, Richards KL, Reddy NM
(2015) Exp Hematol 43: 74-8
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Antibodies, Monoclonal, Murine-Derived, Antineoplastic Agents, Antineoplastic Combined Chemotherapy Protocols, Female, Humans, Hypothyroidism, Immunologic Factors, Interferon-gamma, Interleukin-12, Interleukin-15, Interleukin-6, Lenalidomide, Lymphoma, Large B-Cell, Diffuse, Male, Middle Aged, Rituximab, Severity of Illness Index, Thalidomide, Tumor Necrosis Factor-alpha
Added February 13, 2015
0 Communities
1 Members
0 Resources
23 MeSH Terms
Deficiency of gp91phox inhibits allergic airway inflammation.
Sevin CM, Newcomb DC, Toki S, Han W, Sherrill TP, Boswell MG, Zhu Z, Collins RD, Boyd KL, Goleniewska K, Huckabee MM, Blackwell TS, Peebles RS
(2013) Am J Respir Cell Mol Biol 49: 396-402
MeSH Terms: Animals, Asthma, Bronchoalveolar Lavage Fluid, Cells, Cultured, Dendritic Cells, Female, Gene Deletion, Interleukin-12, Interleukin-13, Lipopolysaccharides, Lung, Membrane Glycoproteins, Mice, Mice, Knockout, NADPH Oxidase 2, NADPH Oxidases, Ovalbumin, Reactive Oxygen Species, Th1 Cells, Th1-Th2 Balance, Th17 Cells, Th2 Cells
Added March 7, 2014
1 Communities
2 Members
0 Resources
22 MeSH Terms
Prostaglandin I2 signaling drives Th17 differentiation and exacerbates experimental autoimmune encephalomyelitis.
Zhou W, Dowell DR, Huckabee MM, Newcomb DC, Boswell MG, Goleniewska K, Lotz MT, Toki S, Yin H, Yao S, Natarajan C, Wu P, Sriram S, Breyer RM, Fitzgerald GA, Peebles RS
(2012) PLoS One 7: e33518
MeSH Terms: Animals, Antineoplastic Agents, Cell Differentiation, Cells, Cultured, Encephalomyelitis, Autoimmune, Experimental, Epoprostenol, Female, Humans, Iloprost, Interleukin-12, Interleukin-17, Interleukin-23, Mice, Mice, Inbred BALB C, Mice, Knockout, Platelet Aggregation Inhibitors, Receptors, Epoprostenol, Spinal Cord, Th17 Cells
Added December 21, 2013
1 Communities
2 Members
0 Resources
19 MeSH Terms
MCP1 SNPs and pulmonary tuberculosis in cohorts from West Africa, the USA and Argentina: lack of association or epistasis with IL12B polymorphisms.
Velez Edwards DR, Tacconelli A, Wejse C, Hill PC, Morris GA, Edwards TL, Gilbert JR, Myers JL, Park YS, Stryjewski ME, Abbate E, Estevan R, Rabna P, Novelli G, Hamilton CD, Adegbola R, Østergaar L, Williams SM, Scott WK, Sirugo G
(2012) PLoS One 7: e32275
MeSH Terms: Adolescent, Adult, African Americans, Aged, Argentina, Blacks, Case-Control Studies, Chemokine CCL2, Epistasis, Genetic, Ethnicity, Female, Gambia, Genetic Predisposition to Disease, Genetic Variation, Guinea-Bissau, Humans, Interleukin-12 Subunit p40, Male, Middle Aged, Polymorphism, Genetic, Tuberculosis, Pulmonary, United States, Whites
Added April 1, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
Cationic amino acid transporter 2 enhances innate immunity during Helicobacter pylori infection.
Barry DP, Asim M, Scull BP, Piazuelo MB, de Sablet T, Lewis ND, Coburn LA, Singh K, Ellies LG, Gobert AP, Chaturvedi R, Wilson KT
(2011) PLoS One 6: e29046
MeSH Terms: Acute Disease, Amino Acid Transport Systems, Basic, Animals, Cell Count, Chronic Disease, Colony Count, Microbial, Dendritic Cells, Gastritis, Helicobacter Infections, Helicobacter pylori, Immunity, Innate, Interleukin-12, Macrophages, Mice, Nitric Oxide Synthase Type II, Stomach, Th1 Cells, Th2 Cells
Added March 5, 2014
0 Communities
3 Members
0 Resources
18 MeSH Terms
CD4+ T cell-derived novel peptide Thp5 induces interleukin-4 production in CD4+ T cells to direct T helper 2 cell differentiation.
Khan MM, Chatterjee S, Dwivedi VP, Pandey NK, Singh Y, Tousif S, Bhavesh NS, Van Kaer L, Das J, Das G
(2012) J Biol Chem 287: 2830-5
MeSH Terms: Animals, Cell Differentiation, Interleukin-12, Interleukin-4, Mice, Mice, Inbred BALB C, Mice, Knockout, Peptides, STAT6 Transcription Factor, Th1 Cells, Th17 Cells, Th2 Cells, Transforming Growth Factor beta, Vasoactive Intestinal Peptide
Added March 20, 2014
0 Communities
1 Members
0 Resources
14 MeSH Terms
Interleukin 12B (IL12B) genetic variation and pulmonary tuberculosis: a study of cohorts from The Gambia, Guinea-Bissau, United States and Argentina.
Morris GA, Edwards DR, Hill PC, Wejse C, Bisseye C, Olesen R, Edwards TL, Gilbert JR, Myers JL, Stryjewski ME, Abbate E, Estevan R, Hamilton CD, Tacconelli A, Novelli G, Brunetti E, Aaby P, Sodemann M, Østergaard L, Adegbola R, Williams SM, Scott WK, Sirugo G
(2011) PLoS One 6: e16656
MeSH Terms: Adolescent, Adult, Aged, Aged, 80 and over, Argentina, Blacks, Case-Control Studies, Cohort Studies, Female, Gambia, Gene Frequency, Genetic Association Studies, Genetic Variation, Genetics, Population, Guinea-Bissau, Humans, Interleukin-12 Subunit p40, Linkage Disequilibrium, Male, Middle Aged, Polymorphism, Single Nucleotide, Tuberculosis, Pulmonary, United States, Young Adult
Added April 1, 2014
0 Communities
1 Members
0 Resources
24 MeSH Terms
Genetic deletion of mPGES-1 abolishes PGE2 production in murine dendritic cells and alters the cytokine profile, but does not affect maturation or migration.
Monrad SU, Kojima F, Kapoor M, Kuan EL, Sarkar S, Randolph GJ, Crofford LJ
(2011) Prostaglandins Leukot Essent Fatty Acids 84: 113-21
MeSH Terms: Animals, Cell Movement, Cricetinae, Cytokines, Dendritic Cells, Dinoprostone, Gene Deletion, Interleukin-12, Intramolecular Oxidoreductases, Lipopolysaccharides, Mice, Mice, Knockout, Prostaglandin-E Synthases, Rats
Added September 18, 2013
0 Communities
1 Members
0 Resources
14 MeSH Terms