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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 234

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Glucose-Dependent miR-125b Is a Negative Regulator of β-Cell Function.
Cheung R, Pizza G, Chabosseau P, Rolando D, Tomas A, Burgoyne T, Wu Z, Salowka A, Thapa A, Macklin A, Cao Y, Nguyen-Tu MS, Dickerson MT, Jacobson DA, Marchetti P, Shapiro J, Piemonti L, de Koning E, Leclerc I, Bouzakri K, Sakamoto K, Smith DM, Rutter GA, Martinez-Sanchez A
(2022) Diabetes 71: 1525-1545
MeSH Terms: AMP-Activated Protein Kinases, Animals, Diabetes Mellitus, Type 2, Glucose, Humans, Insulin-Secreting Cells, Mice, MicroRNAs
Added June 27, 2022
0 Communities
1 Members
0 Resources
8 MeSH Terms
Glucose-6-phosphatase catalytic subunit 2 negatively regulates glucose oxidation and insulin secretion in pancreatic β-cells.
Rahim M, Nakhe AY, Banerjee DR, Overway EM, Bosma KJ, Rosch JC, Oeser JK, Wang B, Lippmann ES, Jacobson DA, O'Brien RM, Young JD
(2022) J Biol Chem 298: 101729
MeSH Terms: Animals, Blood Glucose, Diabetes Mellitus, Type 2, Genome-Wide Association Study, Glucose, Glucose-6-Phosphatase, Insulin, Insulin Secretion, Insulin-Secreting Cells, Mice, Mice, Knockout, Oxidation-Reduction
Added June 27, 2022
0 Communities
1 Members
0 Resources
MeSH Terms
Microtubules regulate pancreatic β-cell heterogeneity via spatiotemporal control of insulin secretion hot spots.
Trogden KP, Lee J, Bracey KM, Ho KH, McKinney H, Zhu X, Arpag G, Folland TG, Osipovich AB, Magnuson MA, Zanic M, Gu G, Holmes WR, Kaverina I
(2021) Elife 10:
MeSH Terms: Animals, Female, Insulin, Insulin Secretion, Insulin-Secreting Cells, Male, Mice, Microtubules, Spatio-Temporal Analysis
Added December 7, 2021
1 Communities
1 Members
0 Resources
9 MeSH Terms
Sex-biased islet β cell dysfunction is caused by the MODY MAFA S64F variant by inducing premature aging and senescence in males.
Walker EM, Cha J, Tong X, Guo M, Liu JH, Yu S, Iacovazzo D, Mauvais-Jarvis F, Flanagan SE, Korbonits M, Stafford J, Jacobson DA, Stein R
(2021) Cell Rep 37: 109813
MeSH Terms: Animals, Animals, Genetically Modified, Blood Glucose, Calcium Signaling, Cell Line, Cellular Senescence, DNA Damage, Diabetes Mellitus, Type 2, Disease Models, Animal, Female, Genetic Predisposition to Disease, Humans, Insulin, Insulin-Secreting Cells, Maf Transcription Factors, Large, Male, Mice, Inbred C57BL, Mutation, Missense, Phenotype, Sex Characteristics, Sex Factors
Added November 23, 2021
0 Communities
1 Members
0 Resources
21 MeSH Terms
TRPM7 is a crucial regulator of pancreatic endocrine development and high-fat-diet-induced β-cell proliferation.
Altman MK, Schaub CM, Dadi PK, Dickerson MT, Zaborska KE, Nakhe AY, Graff SM, Galletta TJ, Amarnath G, Thorson AS, Gu G, Jacobson DA
(2021) Development 148:
MeSH Terms: Animals, Cell Proliferation, Cells, Cultured, Diet, High-Fat, Gene Knockout Techniques, Glucose Intolerance, Homeostasis, Insulin, Insulin Secretion, Insulin-Secreting Cells, Magnesium, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Pancreas, TRPM Cation Channels
Added August 13, 2021
1 Communities
1 Members
0 Resources
17 MeSH Terms
Antagonistic epistasis of Hnf4α and FoxO1 metabolic networks through enhancer interactions in β-cell function.
Kuo T, Du W, Miyachi Y, Dadi PK, Jacobson DA, Segrè D, Accili D
(2021) Mol Metab 53: 101256
MeSH Terms: Animals, Epistasis, Genetic, Forkhead Box Protein O1, Hepatocyte Nuclear Factor 4, Insulin-Secreting Cells, Mice, Mice, Knockout, Mutation
Added June 14, 2021
0 Communities
1 Members
0 Resources
8 MeSH Terms
A KCNK16 mutation causing TALK-1 gain of function is associated with maturity-onset diabetes of the young.
Graff SM, Johnson SR, Leo PJ, Dadi PK, Dickerson MT, Nakhe AY, McInerney-Leo AM, Marshall M, Zaborska KE, Schaub CM, Brown MA, Jacobson DA, Duncan EL
(2021) JCI Insight 6:
MeSH Terms: Animals, Blood Glucose, Calcium Signaling, Channelopathies, Diabetes Mellitus, Type 2, Gain of Function Mutation, Humans, Insulin Secretion, Insulin-Secreting Cells, Membrane Potentials, Mice, Potassium Channels, Tandem Pore Domain
Added June 14, 2021
0 Communities
1 Members
0 Resources
12 MeSH Terms
Sexually dimorphic roles for the type 2 diabetes-associated C2cd4b gene in murine glucose homeostasis.
Mousavy Gharavy SN, Owen BM, Millership SJ, Chabosseau P, Pizza G, Martinez-Sanchez A, Tasoez E, Georgiadou E, Hu M, Fine NHF, Jacobson DA, Dickerson MT, Idevall-Hagren O, Montoya A, Kramer H, Mehta Z, Withers DJ, Ninov N, Gadue PJ, Cardenas-Diaz FL, Cruciani-Guglielmacci C, Magnan C, Ibberson M, Leclerc I, Voz M, Rutter GA
(2021) Diabetologia 64: 850-864
MeSH Terms: Animals, Biomarkers, Blood Glucose, Female, Follicle Stimulating Hormone, Genotype, Homeostasis, Humans, Insulin, Insulin-Secreting Cells, Male, Mice, Inbred C57BL, Mice, Knockout, Phenotype, Pituitary Gland, Sex Characteristics, Weight Gain, Zebrafish, Zebrafish Proteins
Added June 14, 2021
0 Communities
1 Members
0 Resources
19 MeSH Terms
Molecular and functional profiling of human islets: from heterogeneity to human phenotypes.
Arrojo E Drigo R, Roy B, MacDonald PE
(2020) Diabetologia 63: 2095-2101
MeSH Terms: Calcium, Genotype, Humans, Insulin Secretion, Insulin-Secreting Cells, Islets of Langerhans, Phenotype, Single-Cell Analysis, Transcriptome
Added April 14, 2021
0 Communities
1 Members
0 Resources
9 MeSH Terms
Tetraspanin-7 regulation of L-type voltage-dependent calcium channels controls pancreatic β-cell insulin secretion.
Dickerson MT, Dadi PK, Butterworth RB, Nakhe AY, Graff SM, Zaborska KE, Schaub CM, Jacobson DA
(2020) J Physiol 598: 4887-4905
MeSH Terms: Animals, Calcium, Calcium Channels, L-Type, Glucagon-Secreting Cells, Glucose, Insulin, Insulin Secretion, Insulin-Secreting Cells, Mice
Added June 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms