Molecular and epidemiologic characterization of Wilms tumor from Baghdad, Iraq.
Phelps HM, Al-Jadiry MF, Corbitt NM, Pierce JM, Li B, Wei Q, Flores RR, Correa H, Uccini S, Frangoul H, Alsaadawi AR, Al-Badri SAF, Al-Darraji AF, Al-Saeed RM, Al-Hadad SA, Lovvorn Iii HN
(2018) World J Pediatr 14
: 585-593MeSH Terms: Adaptor Proteins, Signal Transducing, Apoptosis Regulatory Proteins, Child, Preschool, DNA Topoisomerases, Type II, Female, Homeodomain Proteins, Humans, Immunohistochemistry, Infant, Insulin-Like Growth Factor II, Iraq, Kidney Neoplasms, Male, Multiplex Polymerase Chain Reaction, Mutation, N-Myc Proto-Oncogene Protein, Nerve Tissue Proteins, Neural Cell Adhesion Molecules, Nuclear Proteins, Poly-ADP-Ribose Binding Proteins, Receptors, Retinoic Acid, Sequence Analysis, DNA, Trans-Activators, Transcription Factors, Tumor Suppressor Protein p53, Tumor Suppressor Proteins, WT1 Proteins, Wilms Tumor, beta CateninAdded January 28, 2019
29 MeSH Terms
YB-1 is elevated in medulloblastoma and drives proliferation in Sonic hedgehog-dependent cerebellar granule neuron progenitor cells and medulloblastoma cells.
Dey A, Robitaille M, Remke M, Maier C, Malhotra A, Gregorieff A, Wrana JL, Taylor MD, Angers S, Kenney AM
(2016) Oncogene 35
: 4256-68MeSH Terms: Animals, Cell Line, Tumor, Cell Proliferation, Cerebellar Neoplasms, Cerebellum, Gene Expression Regulation, Neoplastic, Hedgehog Proteins, Insulin-Like Growth Factor II, Medulloblastoma, Mice, Neural Stem Cells, Signal Transduction, Y-Box-Binding Protein 1Added April 25, 2016
13 MeSH Terms
Insulin-mediated signaling promotes proliferation and survival of glioblastoma through Akt activation.
Gong Y, Ma Y, Sinyuk M, Loganathan S, Thompson RC, Sarkaria JN, Chen W, Lathia JD, Mobley BC, Clark SW, Wang J
(2016) Neuro Oncol 18
: 48-57MeSH Terms: Animals, Antigens, CD, Brain Neoplasms, Cell Proliferation, Cell Survival, Female, Glioblastoma, Humans, Insulin, Insulin-Like Growth Factor I, Insulin-Like Growth Factor II, Mice, Nude, Proto-Oncogene Proteins c-akt, Receptor, IGF Type 1, Receptor, Insulin, Receptors, Somatomedin, Signal Transduction, Tumor Cells, CulturedAdded July 23, 2015
18 MeSH Terms
Value of circulating insulin-like growth factor-associated proteins for the detection of stage I non-small cell lung cancer.
Kubasiak JC, Seder CW, Pithadia R, Basu S, Fhied C, Phillips WW, Daly S, Shersher DD, Yoder MA, Chmielewski G, Edell ES, Maldonado F, Liptay MJ, Borgia JA
(2015) J Thorac Cardiovasc Surg 149
: 727-34.e1-3; discussion 734MeSH Terms: Adult, Aged, Aged, 80 and over, Algorithms, Area Under Curve, Biomarkers, Tumor, Carcinoma, Non-Small-Cell Lung, Cytokines, Female, Humans, Illinois, Insulin-Like Growth Factor Binding Proteins, Insulin-Like Growth Factor I, Insulin-Like Growth Factor II, Lung Neoplasms, Male, Middle Aged, Minnesota, Multivariate Analysis, Neoplasm Staging, Predictive Value of Tests, ROC Curve, Reproducibility of Results, Retrospective Studies, Tomography, X-Ray Computed, Young AdultAdded July 28, 2015
26 MeSH Terms
Organ-specific defects in insulin-like growth factor and insulin receptor signaling in late gestational asymmetric intrauterine growth restriction in Cited1 mutant mice.
Novitskaya T, Baserga M, de Caestecker MP
(2011) Endocrinology 152
: 2503-16MeSH Terms: Animals, Apoptosis Regulatory Proteins, Brain, Disease Models, Animal, Female, Fetal Growth Retardation, Gestational Age, Humans, Insulin-Like Growth Factor I, Insulin-Like Growth Factor II, Kidney, Liver, Mice, Mice, Knockout, Nuclear Proteins, Organ Size, Organ Specificity, Pregnancy, Pregnancy Complications, Receptor, IGF Type 1, Receptor, Insulin, Signal Transduction, Trans-ActivatorsAdded November 21, 2013
23 MeSH Terms
Mutated beta-catenin evades a microRNA-dependent regulatory loop.
Veronese A, Visone R, Consiglio J, Acunzo M, Lupini L, Kim T, Ferracin M, Lovat F, Miotto E, Balatti V, D'Abundo L, Gramantieri L, Bolondi L, Pekarsky Y, Perrotti D, Negrini M, Croce CM
(2011) Proc Natl Acad Sci U S A 108
: 4840-5MeSH Terms: Apoptosis Regulatory Proteins, Cell Line, Tumor, Genetic Loci, HEK293 Cells, Humans, Insulin-Like Growth Factor II, Introns, MicroRNAs, Mutation, Proto-Oncogene Proteins, Transcription Factors, beta CateninAdded December 22, 2013
12 MeSH Terms
IGF-II promoter specific methylation and expression in epithelial ovarian cancer and their associations with disease characteristics.
Qian B, Katsaros D, Lu L, Canuto EM, Benedetto C, Beeghly-Fadiel A, Yu H
(2011) Oncol Rep 25
: 203-13MeSH Terms: Adult, Aged, Aged, 80 and over, DNA Methylation, Disease-Free Survival, Female, Gene Expression Regulation, Neoplastic, Humans, Insulin-Like Growth Factor II, Middle Aged, Neoplasm Staging, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Promoter Regions, Genetic, Reverse Transcriptase Polymerase Chain ReactionAdded February 22, 2016
15 MeSH Terms
Loss of imprinting and marked gene elevation are 2 forms of aberrant IGF2 expression in colorectal cancer.
Cheng YW, Idrees K, Shattock R, Khan SA, Zeng Z, Brennan CW, Paty P, Barany F
(2010) Int J Cancer 127
: 568-77MeSH Terms: Colorectal Neoplasms, DNA Methylation, Genomic Imprinting, Humans, Insulin-Like Growth Factor II, Polymorphism, Genetic, Promoter Regions, GeneticAdded March 28, 2014
7 MeSH Terms
Racial differences in the association between body mass index and serum IGF1, IGF2, and IGFBP3.
Fowke JH, Matthews CE, Yu H, Cai Q, Cohen S, Buchowski MS, Zheng W, Blot WJ
(2010) Endocr Relat Cancer 17
: 51-60MeSH Terms: Adult, African Americans, Age of Onset, Aged, Body Mass Index, Breast Neoplasms, Cross-Sectional Studies, European Continental Ancestry Group, Female, Follow-Up Studies, Genetic Predisposition to Disease, Humans, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor Binding Proteins, Insulin-Like Growth Factor I, Insulin-Like Growth Factor II, Middle Aged, Postmenopause, Premenopause, Prospective Studies, Southeastern United States, Young AdultAdded December 10, 2013
22 MeSH Terms
Acquired resistance to EGFR tyrosine kinase inhibitors in cancer cells is mediated by loss of IGF-binding proteins.
Guix M, Faber AC, Wang SE, Olivares MG, Song Y, Qu S, Rinehart C, Seidel B, Yee D, Arteaga CL, Engelman JA
(2008) J Clin Invest 118
: 2609-19MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Carcinoma, Squamous Cell, Cell Line, Tumor, Cell Survival, Drug Resistance, Neoplasm, ErbB Receptors, Female, Gefitinib, Gene Expression, Humans, Insulin Receptor Substrate Proteins, Insulin-Like Growth Factor Binding Protein 3, Insulin-Like Growth Factor Binding Protein 4, Insulin-Like Growth Factor Binding Proteins, Insulin-Like Growth Factor I, Insulin-Like Growth Factor II, Mice, Mice, Nude, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Phosphorylation, Protein Kinase Inhibitors, Proto-Oncogene Proteins c-akt, Quinazolines, Receptor, ErbB-3, Receptor, IGF Type 1, Xenograft Model Antitumor AssaysAdded March 5, 2014
28 MeSH Terms