Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 14

Publication Record

Connections

Anti-Insulin B Cells Are Poised for Antigen Presentation in Type 1 Diabetes.
Felton JL, Maseda D, Bonami RH, Hulbert C, Thomas JW
(2018) J Immunol 201: 861-873
MeSH Terms: Animals, Antigen Presentation, Autoantibodies, Autoantigens, B-Lymphocyte Subsets, Diabetes Mellitus, Type 1, Female, Immune Tolerance, Inflammation, Insulin, Insulin Antibodies, Lymphocyte Activation, Male, Mice, Mice, Inbred NOD, Mice, Transgenic, Receptors, Antigen, B-Cell
Added July 20, 2018
1 Communities
1 Members
0 Resources
17 MeSH Terms
Reversing Tolerance in Isotype Switch-Competent Anti-Insulin B Lymphocytes.
Williams JM, Bonami RH, Hulbert C, Thomas JW
(2015) J Immunol 195: 853-64
MeSH Terms: Animals, Autoantibodies, Autoimmunity, B-Lymphocytes, CD40 Antigens, Diabetes Mellitus, Type 1, Immune Tolerance, Immunoglobulin G, Immunoglobulin M, Insulin, Insulin Antibodies, Lipopolysaccharides, Mice, Mice, Inbred C57BL, Mice, Transgenic, Molecular Sequence Data, VDJ Exons
Added December 4, 2015
2 Communities
2 Members
0 Resources
17 MeSH Terms
NFATc2 (NFAT1) assists BCR-mediated anergy in anti-insulin B cells.
Bonami RH, Wolfle WT, Thomas JW, Kendall PL
(2014) Mol Immunol 62: 321-8
MeSH Terms: Animals, B-Lymphocyte Subsets, Cells, Cultured, Immune Tolerance, Insulin, Insulin Antibodies, Mice, Mice, Inbred C57BL, NFATC Transcription Factors, Receptors, Antigen, B-Cell, T-Lymphocytes, Transcription, Genetic
Added May 19, 2014
3 Communities
3 Members
0 Resources
12 MeSH Terms
Bruton's tyrosine kinase promotes persistence of mature anti-insulin B cells.
Bonami RH, Sullivan AM, Case JB, Steinberg HE, Hoek KL, Khan WN, Kendall PL
(2014) J Immunol 192: 1459-70
MeSH Terms: Agammaglobulinaemia Tyrosine Kinase, Animals, B-Lymphocytes, Cells, Cultured, Diabetes Mellitus, Type 1, Immunoglobulins, Insulin, Insulin Antibodies, Mice, Mice, Inbred C57BL, Mice, Inbred NOD, Mice, Transgenic, Protein-Tyrosine Kinases, Receptors, Antigen, B-Cell
Added May 19, 2014
1 Communities
2 Members
0 Resources
14 MeSH Terms
Tolerant anti-insulin B cells are effective APCs.
Kendall PL, Case JB, Sullivan AM, Holderness JS, Wells KS, Liu E, Thomas JW
(2013) J Immunol 190: 2519-26
MeSH Terms: Animals, Antigen-Presenting Cells, B-Lymphocyte Subsets, Cells, Cultured, Clonal Anergy, Coculture Techniques, Diabetes Mellitus, Type 1, Immune Tolerance, Insulin Antibodies, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Inbred NOD, Mice, Transgenic, Receptors, Antigen, B-Cell, T-Lymphocyte Subsets
Added December 10, 2013
2 Communities
3 Members
0 Resources
16 MeSH Terms
Reduced diabetes in btk-deficient nonobese diabetic mice and restoration of diabetes with provision of an anti-insulin IgH chain transgene.
Kendall PL, Moore DJ, Hulbert C, Hoek KL, Khan WN, Thomas JW
(2009) J Immunol 183: 6403-12
MeSH Terms: Agammaglobulinaemia Tyrosine Kinase, Animals, Autoantibodies, B-Lymphocyte Subsets, Diabetes Mellitus, Type 1, Immune Tolerance, Immunoglobulin Heavy Chains, Insulin, Insulin Antibodies, Mice, Mice, Inbred C57BL, Mice, Inbred NOD, Mice, Knockout, Mutation, Protein-Tyrosine Kinases, Receptors, Antigen, B-Cell, Signal Transduction, T-Lymphocyte Subsets, Transgenes
Added December 10, 2013
3 Communities
3 Members
0 Resources
19 MeSH Terms
Functional silencing is initiated and maintained in immature anti-insulin B cells.
Henry RA, Acevedo-Suárez CA, Thomas JW
(2009) J Immunol 182: 3432-9
MeSH Terms: Animals, Bone Marrow Cells, CD40 Antigens, Calcium Signaling, Cell Differentiation, Cell Line, Tumor, Cell Proliferation, Cells, Cultured, Clonal Anergy, Gene Silencing, Insulin, Insulin Antibodies, Interleukin-7, Mice, Mice, Inbred C57BL, Mice, Transgenic, Precursor Cells, B-Lymphoid
Added November 6, 2013
2 Communities
2 Members
0 Resources
17 MeSH Terms
Multiple germline kappa light chains generate anti-insulin B cells in nonobese diabetic mice.
Woodward EJ, Thomas JW
(2005) J Immunol 175: 1073-9
MeSH Terms: Animals, Antibody Diversity, Autoantibodies, B-Lymphocyte Subsets, Base Sequence, Bone Marrow Cells, Gene Rearrangement, B-Lymphocyte, Light Chain, Genetic Predisposition to Disease, Immunoglobulin Variable Region, Immunoglobulin kappa-Chains, Insulin, Insulin Antibodies, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Inbred NOD, Mice, Transgenic, Molecular Sequence Data, Multigene Family, Polymorphism, Genetic, Protein Binding, Receptors, Antigen, B-Cell
Added November 6, 2013
2 Communities
1 Members
0 Resources
22 MeSH Terms
Uncoupling of anergy from developmental arrest in anti-insulin B cells supports the development of autoimmune diabetes.
Acevedo-Suárez CA, Hulbert C, Woodward EJ, Thomas JW
(2005) J Immunol 174: 827-33
MeSH Terms: Animals, Antigens, CD, B-Lymphocyte Subsets, B7-2 Antigen, Cell Differentiation, Cell Movement, Cells, Cultured, Clonal Anergy, Diabetes Mellitus, Type 1, Humans, Immunoglobulin M, Insulin Antibodies, Lymphocyte Activation, Membrane Glycoproteins, Mice, Mice, Inbred C57BL, Mice, Inbred NOD, Mice, Transgenic, Spleen, T-Lymphocytes
Added November 6, 2013
2 Communities
1 Members
0 Resources
20 MeSH Terms
The natural autoantibody repertoire of nonobese diabetic mice is highly active.
Thomas JW, Kendall PL, Mitchell HG
(2002) J Immunol 169: 6617-24
MeSH Terms: Amino Acid Sequence, Animals, Antibodies, Antinuclear, Antibodies, Monoclonal, Antibody Diversity, Autoantibodies, Autoimmunity, B-Lymphocytes, Base Sequence, DNA, Diabetes Mellitus, Type 1, Female, Genes, Immunoglobulin, Hybridomas, Immunity, Innate, Insulin Antibodies, Male, Mice, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Inbred NOD, Molecular Sequence Data, Recombination, Genetic, Somatic Hypermutation, Immunoglobulin, Species Specificity
Added December 10, 2013
1 Communities
1 Members
0 Resources
25 MeSH Terms