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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 66

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Metabolic Labeling of Inositol Phosphates and Phosphatidylinositols in Yeast and Mammalian Cells.
Hale AT, Clarke BP, York JD
(2020) Methods Mol Biol 2091: 83-92
MeSH Terms: Animals, Biochemical Phenomena, COS Cells, Cell Line, Chlorocebus aethiops, HT29 Cells, HeLa Cells, Humans, Inositol Phosphates, Phosphatidylinositols, Saccharomyces cerevisiae, Signal Transduction
Added March 30, 2020
0 Communities
1 Members
0 Resources
12 MeSH Terms
Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.
McNamara DE, Dovey CM, Hale AT, Quarato G, Grace CR, Guibao CD, Diep J, Nourse A, Cai CR, Wu H, Kalathur RC, Green DR, York JD, Carette JE, Moldoveanu T
(2019) Cell Chem Biol 26: 863-877.e7
MeSH Terms: Animals, Cell Survival, HT29 Cells, Humans, Inositol Phosphates, Protein Kinases, Sf9 Cells, Spodoptera
Added March 30, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Crystallographic and kinetic analyses of human IPMK reveal disordered domains modulate ATP binding and kinase activity.
Seacrist CD, Blind RD
(2018) Sci Rep 8: 16672
MeSH Terms: Adenosine Triphosphate, Crystallography, Humans, Inositol Phosphates, Kinetics, Phosphorylation, Phosphotransferases (Alcohol Group Acceptor), Protein Binding, Protein Structure, Secondary, Signal Transduction
Added January 19, 2019
0 Communities
1 Members
0 Resources
10 MeSH Terms
MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.
Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE
(2018) Mol Cell 70: 936-948.e7
MeSH Terms: Binding Sites, Cell Death, Colonic Neoplasms, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, HT29 Cells, Herpesvirus 1, Human, Humans, Inositol Phosphates, Jurkat Cells, Mutation, Phosphorylation, Phosphotransferases (Alcohol Group Acceptor), Protein Kinases, Receptor-Interacting Protein Serine-Threonine Kinases, Signal Transduction, Tumor Necrosis Factor-alpha
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Structural basis of ligand binding modes at the neuropeptide Y Y receptor.
Yang Z, Han S, Keller M, Kaiser A, Bender BJ, Bosse M, Burkert K, Kögler LM, Wifling D, Bernhardt G, Plank N, Littmann T, Schmidt P, Yi C, Li B, Ye S, Zhang R, Xu B, Larhammar D, Stevens RC, Huster D, Meiler J, Zhao Q, Beck-Sickinger AG, Buschauer A, Wu B
(2018) Nature 556: 520-524
MeSH Terms: Arginine, Binding Sites, Crystallography, X-Ray, Dihydropyridines, Diphenylacetic Acids, Humans, Inositol Phosphates, Ligands, Molecular Docking Simulation, Mutant Proteins, Mutation, Neuropeptide Y, Nuclear Magnetic Resonance, Biomolecular, Phenylurea Compounds, Protein Binding, Receptors, Neuropeptide Y, Structure-Activity Relationship, Substrate Specificity
Added March 21, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
The Par3 polarity protein is an exocyst receptor essential for mammary cell survival.
Ahmed SM, Macara IG
(2017) Nat Commun 8: 14867
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Apoptosis, Cadherins, Cell Adhesion Molecules, Cell Cycle Proteins, Cell Line, Cell Polarity, Cell Survival, Enzyme Activation, Epithelial Cells, Female, Gene Knockdown Techniques, Golgi Apparatus, Humans, Lysine, Mammary Glands, Animal, Models, Biological, PTEN Phosphohydrolase, Phosphatidylinositol Phosphates, Phosphorylation, Protein Domains, Proto-Oncogene Proteins c-akt, Vesicular Transport Proteins, rab GTP-Binding Proteins
Added April 26, 2017
0 Communities
1 Members
0 Resources
25 MeSH Terms
IQGAP1 makes PI(3)K signalling as easy as PIP, PIP, PIP.
Rameh LE, Mackey AM
(2016) Nat Cell Biol 18: 1263-1265
MeSH Terms: Animals, Humans, Models, Biological, Neoplasms, Phosphatidylinositol 3-Kinases, Phosphatidylinositol Phosphates, Phosphorylation, Signal Transduction, ras GTPase-Activating Proteins
Added November 26, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
VU0477573: Partial Negative Allosteric Modulator of the Subtype 5 Metabotropic Glutamate Receptor with In Vivo Efficacy.
Nickols HH, Yuh JP, Gregory KJ, Morrison RD, Bates BS, Stauffer SR, Emmitte KA, Bubser M, Peng W, Nedelcovych MT, Thompson A, Lv X, Xiang Z, Daniels JS, Niswender CM, Lindsley CW, Jones CK, Conn PJ
(2016) J Pharmacol Exp Ther 356: 123-36
MeSH Terms: Allosteric Regulation, Animals, Anti-Anxiety Agents, Astrocytes, Behavior, Animal, Brain, Dose-Response Relationship, Drug, Drug Discovery, GABA Agonists, HEK293 Cells, Humans, Inositol Phosphates, MAP Kinase Signaling System, Membrane Potentials, Mice, Mice, Inbred C57BL, Picolinic Acids, Pyridines, Radioligand Assay, Rats, Receptor, Metabotropic Glutamate 5, Synaptic Transmission
Added February 18, 2016
0 Communities
3 Members
0 Resources
22 MeSH Terms
PI(3,5)P2 controls endosomal branched actin dynamics by regulating cortactin-actin interactions.
Hong NH, Qi A, Weaver AM
(2015) J Cell Biol 210: 753-69
MeSH Terms: Actin-Related Protein 2-3 Complex, Actins, Binding Sites, Cell Line, Tumor, Cortactin, Endosomes, Enzyme Activation, HeLa Cells, Humans, Phosphatidylinositol Phosphates, Protein Binding, Protein Structure, Tertiary, RNA Interference, RNA, Small Interfering, Wiskott-Aldrich Syndrome Protein, Neuronal, rab GTP-Binding Proteins
Added February 15, 2016
1 Communities
1 Members
0 Resources
16 MeSH Terms
An excitable compass guides chemotaxis?
Holmes WR
(2014) Biophys J 106: 989-90
MeSH Terms: Chemotaxis, Dictyostelium, Phosphatidylinositol Phosphates, Signal Transduction
Added February 26, 2016
0 Communities
1 Members
0 Resources
4 MeSH Terms