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Results: 1 to 10 of 10

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Steady-state pharmacokinetics and tolerability of indinavir-lopinavir/r combination therapy in antiretroviral-experienced patients.
Antoniou T, Tseng AL, van Heeswijk RP, Walker SE, Giguere P, Phillips EJ
(2005) Ther Drug Monit 27: 779-81
MeSH Terms: Adult, Area Under Curve, Chromatography, High Pressure Liquid, Drug Therapy, Combination, Female, HIV Infections, HIV Protease Inhibitors, Humans, Hypertriglyceridemia, Indinavir, Lopinavir, Male, Metabolic Clearance Rate, Pyrimidinones
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Milk thistle and indinavir: a randomized controlled pharmacokinetics study and meta-analysis.
Mills E, Wilson K, Clarke M, Foster B, Walker S, Rachlis B, DeGroot N, Montori VM, Gold W, Phillips E, Myers S, Gallicano K
(2005) Eur J Clin Pharmacol 61: 1-7
MeSH Terms: Adult, Area Under Curve, Drug Interactions, HIV Protease Inhibitors, Half-Life, Humans, Indinavir, Male, Meta-Analysis as Topic, Milk Thistle, Plant Preparations
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Effects of ritonavir on indinavir pharmacokinetics in cerebrospinal fluid and plasma.
Haas DW, Johnson B, Nicotera J, Bailey VL, Harris VL, Bowles FB, Raffanti S, Schranz J, Finn TS, Saah AJ, Stone J
(2003) Antimicrob Agents Chemother 47: 2131-7
MeSH Terms: Adult, Anti-HIV Agents, Blood-Brain Barrier, Drug Therapy, Combination, Female, HIV Infections, HIV Protease Inhibitors, Humans, Immunoglobulin G, Indinavir, Lamivudine, Male, Middle Aged, Ritonavir, Stavudine
Added March 13, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
Treatment with indinavir, efavirenz, and adefovir after failure of nelfinavir therapy.
Saah AJ, Haas DW, DiNubile MJ, Chen J, Holder DJ, Rhodes RR, Shivaprakash M, Bakshi KK, Danovich RM, Graham DJ, Condra JH
(2003) J Infect Dis 187: 1157-62
MeSH Terms: Adenine, Adult, Alkynes, Anti-HIV Agents, Benzoxazines, Cyclopropanes, Drug Resistance, Viral, Female, HIV, HIV Infections, HIV Protease Inhibitors, Humans, Indinavir, Male, Middle Aged, Nelfinavir, Organophosphonates, Oxazines, Treatment Failure
Added March 13, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Therapy with efavirenz plus indinavir in patients with extensive prior nucleoside reverse-transcriptase inhibitor experience: a randomized, double-blind, placebo-controlled trial.
Haas DW, Fessel WJ, Delapenha RA, Kessler H, Seekins D, Kaplan M, Ruiz NM, Ploughman LM, Labriola DF, Manion DJ
(2001) J Infect Dis 183: 392-400
MeSH Terms: Adult, Alkynes, Anti-HIV Agents, Benzoxazines, CD4 Lymphocyte Count, Cyclopropanes, Double-Blind Method, Drug Therapy, Combination, Female, HIV Infections, HIV-1, Humans, Indinavir, Male, Middle Aged, Oxazines, RNA, Viral, Reverse Transcriptase Inhibitors, Treatment Outcome
Added March 13, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms
Steady-state pharmacokinetics of indinavir in cerebrospinal fluid and plasma among adults with human immunodeficiency virus type 1 infection.
Haas DW, Stone J, Clough LA, Johnson B, Spearman P, Harris VL, Nicotera J, Johnson RH, Raffanti S, Zhong L, Bergqwist P, Chamberlin S, Hoagland V, Ju WD
(2000) Clin Pharmacol Ther 68: 367-74
MeSH Terms: Acquired Immunodeficiency Syndrome, Administration, Oral, Adult, Area Under Curve, Blood-Brain Barrier, Drug Administration Schedule, HIV Protease Inhibitors, HIV-1, Humans, Indinavir, RNA, Messenger, RNA, Viral
Added March 13, 2015
0 Communities
1 Members
0 Resources
12 MeSH Terms
Comparative studies of two-times-daily versus three-times-daily indinavir in combination with zidovudine and lamivudine.
Haas DW, Arathoon E, Thompson MA, de Jesus Pedro R, Gallant JE, Uip DE, Currier J, Noriega LM, Lewi DS, Uribe P, Benetucci L, Cahn P, Paar D, White AC, Collier AC, Ramirez-Ronda CH, Harvey C, Chung MO, Mehrotra D, Chodakewitz J, Nguyen BY, Protocol 054/069 Study Teams
(2000) AIDS 14: 1973-8
MeSH Terms: Adult, Anti-HIV Agents, Antiretroviral Therapy, Highly Active, CD4 Lymphocyte Count, Drug Administration Schedule, HIV Infections, HIV-1, Humans, Indinavir, Lamivudine, Pilot Projects, RNA, Viral, Reverse Transcriptase Inhibitors, Treatment Outcome, Viral Load, Zidovudine
Added March 13, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Elucidation of distinct ligand binding sites for cytochrome P450 3A4.
Hosea NA, Miller GP, Guengerich FP
(2000) Biochemistry 39: 5929-39
MeSH Terms: Binding Sites, Binding, Competitive, Catalysis, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme Inhibitors, Cytochrome P-450 Enzyme System, HIV Protease Inhibitors, Humans, Indinavir, Ligands, Mixed Function Oxygenases, Models, Chemical, Oligopeptides, Oxidation-Reduction, Structure-Activity Relationship, Substrate Specificity
Added March 5, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Factors that predict incomplete virological response to protease inhibitor-based antiretroviral therapy.
Clough LA, D'Agata E, Raffanti S, Haas DW
(1999) Clin Infect Dis 29: 75-81; discussion 82-4
MeSH Terms: Adult, Anti-HIV Agents, Cohort Studies, Drug Therapy, Combination, Female, HIV Infections, HIV Protease Inhibitors, HIV-1, Humans, Indinavir, Male, Nelfinavir, Prognosis, Retrospective Studies, Ritonavir
Added March 13, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
The drug transporter P-glycoprotein limits oral absorption and brain entry of HIV-1 protease inhibitors.
Kim RB, Fromm MF, Wandel C, Leake B, Wood AJ, Roden DM, Wilkinson GR
(1998) J Clin Invest 101: 289-94
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Animals, Caco-2 Cells, HIV Protease, HIV Protease Inhibitors, Humans, Indinavir, Intestinal Absorption, Male, Mice, Nelfinavir, Saquinavir
Added March 27, 2014
0 Communities
1 Members
0 Resources
12 MeSH Terms