Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 8 of 8

Publication Record

Connections

LRRC8A channels support TNF╬▒-induced superoxide production by Nox1 which is required for receptor endocytosis.
Choi H, Ettinger N, Rohrbough J, Dikalova A, Nguyen HN, Lamb FS
(2016) Free Radic Biol Med 101: 413-423
MeSH Terms: Cell Line, Cyclopentanes, Endocytosis, Gene Expression Regulation, HEK293 Cells, Humans, Indans, JNK Mitogen-Activated Protein Kinases, Membrane Proteins, Myocytes, Smooth Muscle, NADPH Oxidase 1, NF-kappa B, Phosphorylation, Protein Subunits, RNA, Small Interfering, Receptors, Tumor Necrosis Factor, Type I, Signal Transduction, Superoxide Dismutase, Superoxides, Tumor Necrosis Factor-alpha, Vascular Cell Adhesion Molecule-1
Added March 26, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
The effect of donepezil treatment on cardiovascular mortality.
Sato K, Urbano R, Yu C, Yamasaki F, Sato T, Jordan J, Robertson D, Diedrich A
(2010) Clin Pharmacol Ther 88: 335-8
MeSH Terms: Aged, Aged, 80 and over, Alzheimer Disease, Cardiovascular Diseases, Cholinesterase Inhibitors, Cohort Studies, Dementia, Vascular, Donepezil, Female, Follow-Up Studies, Humans, Indans, Male, Nootropic Agents, Piperidines, Proportional Hazards Models, Retrospective Studies
Added December 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
The mGluR2 positive allosteric modulator BINA decreases cocaine self-administration and cue-induced cocaine-seeking and counteracts cocaine-induced enhancement of brain reward function in rats.
Jin X, Semenova S, Yang L, Ardecky R, Sheffler DJ, Dahl R, Conn PJ, Cosford ND, Markou A
(2010) Neuropsychopharmacology 35: 2021-36
MeSH Terms: Amino Acids, Analysis of Variance, Animals, Behavior, Animal, Biphenyl Compounds, Brain, Bridged Bicyclo Compounds, Heterocyclic, Cell Line, Transformed, Cocaine, Cues, Dopamine Uptake Inhibitors, Dose-Response Relationship, Drug, Drug Interactions, Excitatory Amino Acid Agonists, Extinction, Psychological, Feeding Behavior, Glutamic Acid, Humans, Indans, Male, Rats, Rats, Wistar, Receptors, Metabotropic Glutamate, Reinforcement Schedule, Reward, Self Administration, Time Factors
Added February 19, 2015
0 Communities
1 Members
0 Resources
27 MeSH Terms
Selective potentiation of the metabotropic glutamate receptor subtype 2 blocks phencyclidine-induced hyperlocomotion and brain activation.
Hackler EA, Byun NE, Jones CK, Williams JM, Baheza R, Sengupta S, Grier MD, Avison M, Conn PJ, Gore JC
(2010) Neuroscience 168: 209-18
MeSH Terms: Allosteric Regulation, Animals, Biphenyl Compounds, Brain, Drug Evaluation, Preclinical, Indans, Magnetic Resonance Imaging, Male, Motor Activity, Oxygen, Phencyclidine, Rats, Rats, Sprague-Dawley, Receptors, Metabotropic Glutamate, Receptors, N-Methyl-D-Aspartate
Added March 7, 2014
0 Communities
5 Members
0 Resources
15 MeSH Terms
Promise of mGluR2/3 activators in psychiatry.
Conn PJ, Jones CK
(2009) Neuropsychopharmacology 34: 248-9
MeSH Terms: Animals, Anxiety Disorders, Biphenyl Compounds, Drug Delivery Systems, Humans, Indans, Mental Disorders, Pyridines, Receptors, Metabotropic Glutamate, Schizophrenia, Sulfonamides
Added February 19, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Effects of galantamine on measures of attention: results from 2 clinical trials in Alzheimer disease patients with comparisons to donepezil.
Galvin JE, Cornblatt B, Newhouse P, Ancoli-Israel S, Wesnes K, Williamson D, Zhu Y, Sorra K, Amatniek J
(2008) Alzheimer Dis Assoc Disord 22: 30-8
MeSH Terms: Aged, Aged, 80 and over, Alzheimer Disease, Attention, Cholinesterase Inhibitors, Donepezil, Double-Blind Method, Female, Galantamine, Humans, Indans, Male, Middle Aged, Neuropsychological Tests, Piperidines, Single-Blind Method
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
A selective positive allosteric modulator of metabotropic glutamate receptor subtype 2 blocks a hallucinogenic drug model of psychosis.
Benneyworth MA, Xiang Z, Smith RL, Garcia EE, Conn PJ, Sanders-Bush E
(2007) Mol Pharmacol 72: 477-84
MeSH Terms: 2,5-Dimethoxy-4-Methylamphetamine, Allosteric Regulation, Animals, Biphenyl Compounds, Excitatory Postsynaptic Potentials, Hallucinogens, Indans, Male, Mice, Mice, Inbred ICR, Prefrontal Cortex, Proto-Oncogene Proteins c-fos, Psychotic Disorders, Rats, Rats, Sprague-Dawley, Receptors, Metabotropic Glutamate
Added February 19, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice.
Galici R, Jones CK, Hemstapat K, Nong Y, Echemendia NG, Williams LC, de Paulis T, Conn PJ
(2006) J Pharmacol Exp Ther 318: 173-85
MeSH Terms: Allosteric Regulation, Animals, Anti-Anxiety Agents, Antipsychotic Agents, Biphenyl Compounds, CHO Cells, Cricetinae, Dose-Response Relationship, Drug, Excitatory Postsynaptic Potentials, Indans, Male, Mice, Mice, Inbred C57BL, Motor Activity, Rats, Rats, Sprague-Dawley, Receptors, Metabotropic Glutamate
Added February 19, 2015
0 Communities
2 Members
0 Resources
17 MeSH Terms