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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 15

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Dominant protection from HLA-linked autoimmunity by antigen-specific regulatory T cells.
Ooi JD, Petersen J, Tan YH, Huynh M, Willett ZJ, Ramarathinam SH, Eggenhuizen PJ, Loh KL, Watson KA, Gan PY, Alikhan MA, Dudek NL, Handel A, Hudson BG, Fugger L, Power DA, Holt SG, Coates PT, Gregersen JW, Purcell AW, Holdsworth SR, La Gruta NL, Reid HH, Rossjohn J, Kitching AR
(2017) Nature 545: 243-247
MeSH Terms: Animals, Anti-Glomerular Basement Membrane Disease, Autoimmunity, Base Sequence, CD4-Positive T-Lymphocytes, Collagen Type IV, Cytokines, Female, Forkhead Transcription Factors, HLA-DR Serological Subtypes, HLA-DR1 Antigen, Humans, Immunodominant Epitopes, Male, Mice, Mice, Transgenic, Models, Molecular, T-Lymphocytes, Regulatory
Added June 2, 2017
1 Communities
1 Members
0 Resources
18 MeSH Terms
Human Antibodies that Recognize Novel Immunodominant Quaternary Epitopes on the HIV-1 Env Protein.
Hicar MD, Chen X, Sulli C, Barnes T, Goodman J, Sojar H, Briney B, Willis J, Chukwuma VU, Kalams SA, Doranz BJ, Spearman P, Crowe JE
(2016) PLoS One 11: e0158861
MeSH Terms: Antibodies, Monoclonal, Antibodies, Neutralizing, B-Lymphocytes, HIV Antibodies, HIV Envelope Protein gp41, HIV Infections, HIV-1, Humans, Immunodominant Epitopes, Protein Domains, Recombinant Proteins, env Gene Products, Human Immunodeficiency Virus
Added April 13, 2017
0 Communities
1 Members
0 Resources
12 MeSH Terms
Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody.
Kong R, Xu K, Zhou T, Acharya P, Lemmin T, Liu K, Ozorowski G, Soto C, Taft JD, Bailer RT, Cale EM, Chen L, Choi CW, Chuang GY, Doria-Rose NA, Druz A, Georgiev IS, Gorman J, Huang J, Joyce MG, Louder MK, Ma X, McKee K, O'Dell S, Pancera M, Yang Y, Blanchard SC, Mothes W, Burton DR, Koff WC, Connors M, Ward AB, Kwong PD, Mascola JR
(2016) Science 352: 828-33
MeSH Terms: AIDS Vaccines, Amino Acid Sequence, Antibodies, Neutralizing, Antibodies, Viral, B-Lymphocytes, Crystallography, X-Ray, HIV Envelope Protein gp120, HIV Envelope Protein gp41, HIV-1, Humans, Hydrophobic and Hydrophilic Interactions, Immunodominant Epitopes, Molecular Sequence Data, Peptides, Protein Conformation, Viral Fusion Proteins, Virus Internalization
Added May 3, 2017
0 Communities
1 Members
0 Resources
17 MeSH Terms
Association of VH4-59 Antibody Variable Gene Usage with Recognition of an Immunodominant Epitope on the HIV-1 Gag Protein.
Chukwuma VU, Hicar MD, Chen X, Nicholas KJ, Joyner A, Kalams SA, Landucci G, Forthal DN, Spearman PW, Crowe JE
(2015) PLoS One 10: e0133509
MeSH Terms: Amino Acid Sequence, Antibodies, Monoclonal, B-Lymphocytes, Gene Products, gag, Genes, Immunoglobulin, HIV Antibodies, HIV Infections, HIV-1, Humans, Immunodominant Epitopes, Molecular Sequence Data, Neutralization Tests, T-Lymphocytes, Virion
Added January 26, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Discovering naturally processed antigenic determinants that confer protective T cell immunity.
Gilchuk P, Spencer CT, Conant SB, Hill T, Gray JJ, Niu X, Zheng M, Erickson JJ, Boyd KL, McAfee KJ, Oseroff C, Hadrup SR, Bennink JR, Hildebrand W, Edwards KM, Crowe JE, Williams JV, Buus S, Sette A, Schumacher TN, Link AJ, Joyce S
(2013) J Clin Invest 123: 1976-87
MeSH Terms: Animals, Antigen Presentation, Antigens, CD8-Positive T-Lymphocytes, Epitopes, Epitopes, T-Lymphocyte, HeLa Cells, Histocompatibility Antigens Class I, Humans, Immunodominant Epitopes, Mass Spectrometry, Mice, Mice, Transgenic, Peptides, Phenotype, T-Lymphocytes, Vaccinia virus
Added March 20, 2014
1 Communities
5 Members
0 Resources
17 MeSH Terms
Enhancement of the CD8+ T cell response to a subdominant epitope of respiratory syncytial virus by deletion of an immunodominant epitope.
Mok H, Lee S, Wright DW, Crowe JE
(2008) Vaccine 26: 4775-82
MeSH Terms: Amino Acid Substitution, Animals, CD8-Positive T-Lymphocytes, Epitopes, T-Lymphocyte, Female, Immunodominant Epitopes, Mice, Mice, Inbred BALB C, Plasmids, Respiratory Syncytial Virus Vaccines, Respiratory Syncytial Viruses, Vaccines, DNA, Viral Proteins
Added August 6, 2012
0 Communities
1 Members
0 Resources
13 MeSH Terms
Functional maturation of the human antibody response to rotavirus.
Kallewaard NL, McKinney BA, Gu Y, Chen A, Prasad BV, Crowe JE
(2008) J Immunol 180: 3980-9
MeSH Terms: Antibodies, Viral, Antigens, Viral, Binding Sites, Antibody, Capsid Proteins, Humans, Immunodominant Epitopes, Immunoglobulin D, Immunoglobulin Fab Fragments, Immunoglobulin Heavy Chains, Immunoglobulin Variable Region, Kinetics, Respiratory Syncytial Viruses, Rotavirus, Somatic Hypermutation, Immunoglobulin
Added August 6, 2012
0 Communities
1 Members
0 Resources
14 MeSH Terms
Immunodominance of the VH1-46 antibody gene segment in the primary repertoire of human rotavirus-specific B cells is reduced in the memory compartment through somatic mutation of nondominant clones.
Tian C, Luskin GK, Dischert KM, Higginbotham JN, Shepherd BE, Crowe JE
(2008) J Immunol 180: 3279-88
MeSH Terms: Adult, Antibodies, Viral, Antigens, Viral, B-Lymphocyte Subsets, Capsid Proteins, Clone Cells, Epitopes, B-Lymphocyte, Humans, Immunodominant Epitopes, Immunoglobulin Class Switching, Immunoglobulin Heavy Chains, Immunoglobulin Variable Region, Immunologic Memory, Middle Aged, Resting Phase, Cell Cycle, Rotavirus, Somatic Hypermutation, Immunoglobulin
Added August 6, 2012
0 Communities
1 Members
0 Resources
17 MeSH Terms
Escape from the dominant HLA-B27-restricted cytotoxic T-lymphocyte response in Gag is associated with a dramatic reduction in human immunodeficiency virus type 1 replication.
Schneidewind A, Brockman MA, Yang R, Adam RI, Li B, Le Gall S, Rinaldo CR, Craggs SL, Allgaier RL, Power KA, Kuntzen T, Tung CS, LaBute MX, Mueller SM, Harrer T, McMichael AJ, Goulder PJ, Aiken C, Brander C, Kelleher AD, Allen TM
(2007) J Virol 81: 12382-93
MeSH Terms: Amino Acid Sequence, Capsid, Cyclosporine, HIV Infections, HIV-1, HLA-B27 Antigen, Humans, Immunodominant Epitopes, Molecular Sequence Data, Mutation, T-Lymphocytes, Cytotoxic, Virus Replication, gag Gene Products, Human Immunodeficiency Virus
Added February 19, 2015
0 Communities
1 Members
0 Resources
13 MeSH Terms
Tissue-specific regulation of CD8+ T-lymphocyte immunodominance in respiratory syncytial virus infection.
Lee S, Miller SA, Wright DW, Rock MT, Crowe JE
(2007) J Virol 81: 2349-58
MeSH Terms: Amino Acid Sequence, Animals, Antigens, Viral, CD8-Positive T-Lymphocytes, Female, H-2 Antigens, Humans, Immunodominant Epitopes, Interferon-gamma, Mice, Mice, Inbred BALB C, Respiratory Syncytial Virus Infections, Respiratory Syncytial Virus, Human, Viral Matrix Proteins
Added August 6, 2012
0 Communities
1 Members
0 Resources
14 MeSH Terms