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Immunotherapy and Targeted Therapy for Small Cell Lung Cancer: There Is Hope.
Lehman JM, Gwin ME, Massion PP
(2017) Curr Oncol Rep 19: 49
MeSH Terms: Genes, cdc, Humans, Immunoconjugates, Immunotherapy, Molecular Targeted Therapy, Small Cell Lung Carcinoma
Added January 29, 2018
0 Communities
2 Members
0 Resources
6 MeSH Terms
Antibody-Conjugated Single Quantum Dot Tracking of Membrane Neurotransmitter Transporters in Primary Neuronal Cultures.
Bailey DM, Kovtun O, Rosenthal SJ
(2017) Methods Mol Biol 1570: 165-177
MeSH Terms: Algorithms, Animals, Fluorescent Antibody Technique, Immunoconjugates, Models, Theoretical, Molecular Imaging, Neurons, Neurotransmitter Transport Proteins, Primary Cell Culture, Quantum Dots, Rats, Single Molecule Imaging, Statistics as Topic
Added April 3, 2018
0 Communities
2 Members
0 Resources
MeSH Terms
A DLL3-targeted antibody-drug conjugate eradicates high-grade pulmonary neuroendocrine tumor-initiating cells in vivo.
Saunders LR, Bankovich AJ, Anderson WC, Aujay MA, Bheddah S, Black K, Desai R, Escarpe PA, Hampl J, Laysang A, Liu D, Lopez-Molina J, Milton M, Park A, Pysz MA, Shao H, Slingerland B, Torgov M, Williams SA, Foord O, Howard P, Jassem J, Badzio A, Czapiewski P, Harpole DH, Dowlati A, Massion PP, Travis WD, Pietanza MC, Poirier JT, Rudin CM, Stull RA, Dylla SJ
(2015) Sci Transl Med 7: 302ra136
MeSH Terms: Animals, Antibodies, Monoclonal, Antineoplastic Agents, Female, Humans, Immunoconjugates, Intracellular Signaling Peptides and Proteins, Lung Neoplasms, Membrane Proteins, Mice, Mice, Inbred NOD, Mice, SCID, Neuroendocrine Tumors, Xenograft Model Antitumor Assays
Added February 16, 2016
0 Communities
1 Members
0 Resources
14 MeSH Terms
Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: follow-up 1 year after cessation of treatment.
Orban T, Bundy B, Becker DJ, Dimeglio LA, Gitelman SE, Goland R, Gottlieb PA, Greenbaum CJ, Marks JB, Monzavi R, Moran A, Peakman M, Raskin P, Russell WE, Schatz D, Wherrett DK, Wilson DM, Krischer JP, Skyler JS, Type 1 Diabetes TrialNet Abatacept Study Group
(2014) Diabetes Care 37: 1069-75
MeSH Terms: Abatacept, Adolescent, Adult, C-Peptide, Child, Diabetes Mellitus, Type 1, Female, Follow-Up Studies, Glycated Hemoglobin A, Humans, Immunoconjugates, Immunosuppressive Agents, Male, Placebos, Withholding Treatment, Young Adult
Added March 24, 2014
0 Communities
1 Members
0 Resources
16 MeSH Terms
Three-dimensional molecular imaging with photothermal optical coherence tomography.
Skala MC, Crow MJ, Wax A, Izatt JA
(2013) Methods Mol Biol 1026: 85-92
MeSH Terms: Cell Line, Tumor, Darkness, Gold, Hot Temperature, Humans, Imaging, Three-Dimensional, Immunoconjugates, Metal Nanoparticles, Molecular Imaging, Tissue Culture Techniques, Tomography, Optical Coherence
Added March 11, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
A chemically programmed antibody is a long-lasting and potent inhibitor of influenza neuraminidase.
Hayakawa M, Toda N, Carrillo N, Thornburg NJ, Crowe JE, Barbas CF
(2012) Chembiochem 13: 2191-5
MeSH Terms: Animals, Antibodies, Monoclonal, Antiviral Agents, Click Chemistry, Fructose-Bisphosphate Aldolase, Humans, Immunoconjugates, Influenza A virus, Influenza, Human, Mice, Models, Molecular, Neuraminidase, Orthomyxoviridae Infections, Zanamivir
Added October 28, 2012
0 Communities
1 Members
0 Resources
14 MeSH Terms
Co-stimulation modulation with abatacept in patients with recent-onset type 1 diabetes: a randomised, double-blind, placebo-controlled trial.
Orban T, Bundy B, Becker DJ, DiMeglio LA, Gitelman SE, Goland R, Gottlieb PA, Greenbaum CJ, Marks JB, Monzavi R, Moran A, Raskin P, Rodriguez H, Russell WE, Schatz D, Wherrett D, Wilson DM, Krischer JP, Skyler JS, Type 1 Diabetes TrialNet Abatacept Study Group
(2011) Lancet 378: 412-9
MeSH Terms: Abatacept, Adolescent, Adult, Autoimmunity, Child, Diabetes Mellitus, Type 1, Double-Blind Method, Female, Humans, Immunoconjugates, Immunosuppressive Agents, Insulin-Secreting Cells, Male, Randomized Controlled Trials as Topic, T-Lymphocytes, Young Adult
Added October 24, 2013
0 Communities
2 Members
0 Resources
16 MeSH Terms
Inhibition and genetic ablation of the B7/CD28 T-cell costimulation axis prevents experimental hypertension.
Vinh A, Chen W, Blinder Y, Weiss D, Taylor WR, Goronzy JJ, Weyand CM, Harrison DG, Guzik TJ
(2010) Circulation 122: 2529-37
MeSH Terms: Abatacept, Angiotensin II, Animals, Antihypertensive Agents, B7-1 Antigen, B7-2 Antigen, CD28 Antigens, Cells, Cultured, Gene Deletion, Hypertension, Immunoconjugates, Immunosuppressive Agents, Ligands, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Knockout, Random Allocation, T-Lymphocytes
Added December 10, 2013
1 Communities
1 Members
0 Resources
19 MeSH Terms
The immunoconjugate "icon" targets aberrantly expressed endothelial tissue factor causing regression of endometriosis.
Krikun G, Hu Z, Osteen K, Bruner-Tran KL, Schatz F, Taylor HS, Toti P, Arcuri F, Konigsberg W, Garen A, Booth CJ, Lockwood CJ
(2010) Am J Pathol 176: 1050-6
MeSH Terms: Adult, Animals, CHO Cells, Cricetinae, Cricetulus, Drug Delivery Systems, Endometriosis, Endothelium, Vascular, Female, Humans, Immunoconjugates, Immunoglobulin Fc Fragments, Immunotherapy, Mice, Mice, Nude, Middle Aged, Neovascularization, Pathologic, Peritoneal Diseases, Thromboplastin, Transplantation, Heterologous
Added May 29, 2014
0 Communities
2 Members
0 Resources
20 MeSH Terms
PEGylation strategies for active targeting of PLA/PLGA nanoparticles.
Betancourt T, Byrne JD, Sunaryo N, Crowder SW, Kadapakkam M, Patel S, Casciato S, Brannon-Peppas L
(2009) J Biomed Mater Res A 91: 263-76
MeSH Terms: Animals, Drug Delivery Systems, Immunoconjugates, Lactic Acid, Mice, Nanoparticles, Poloxamer, Polyesters, Polyethylene Glycols, Polyglycolic Acid, Polylactic Acid-Polyglycolic Acid Copolymer, Polymers, Surface Properties
Added September 24, 2012
0 Communities
1 Members
0 Resources
13 MeSH Terms