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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 20

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A dihydro-pyrido-indole potently inhibits HSV-1 infection by interfering the viral immediate early transcriptional events.
Bag P, Ojha D, Mukherjee H, Halder UC, Mondal S, Biswas A, Sharon A, Van Kaer L, Chakrabarty S, Das G, Mitra D, Chattopadhyay D
(2014) Antiviral Res 105: 126-34
MeSH Terms: Animals, Antiviral Agents, Disease Models, Animal, Female, Harmaline, Herpes Simplex, Herpesvirus 1, Human, Immediate-Early Proteins, Mice, Inbred BALB C, Rubiaceae, Transcription, Genetic
Added March 20, 2014
0 Communities
1 Members
0 Resources
11 MeSH Terms
ATR and ATRIP are recruited to herpes simplex virus type 1 replication compartments even though ATR signaling is disabled.
Mohni KN, Livingston CM, Cortez D, Weller SK
(2010) J Virol 84: 12152-64
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Ataxia Telangiectasia Mutated Proteins, Blotting, Western, Cell Cycle Proteins, Chlorocebus aethiops, DNA Damage, DNA Primers, DNA-Binding Proteins, Fluorescent Antibody Technique, HeLa Cells, Herpesvirus 1, Human, Humans, Immediate-Early Proteins, Immunoprecipitation, Phosphorylation, Plasmids, Protein Serine-Threonine Kinases, Replication Protein A, Signal Transduction, Ubiquitin-Protein Ligases, Vero Cells, Virus Replication
Added March 11, 2014
0 Communities
1 Members
0 Resources
23 MeSH Terms
The kinesin KIF1Bbeta acts downstream from EglN3 to induce apoptosis and is a potential 1p36 tumor suppressor.
Schlisio S, Kenchappa RS, Vredeveld LC, George RE, Stewart R, Greulich H, Shahriari K, Nguyen NV, Pigny P, Dahia PL, Pomeroy SL, Maris JM, Look AT, Meyerson M, Peeper DS, Carter BD, Kaelin WG
(2008) Genes Dev 22: 884-93
MeSH Terms: Animals, Animals, Newborn, Apoptosis, Cells, Cultured, Child, Chromosome Mapping, Chromosomes, Mammalian, DNA-Binding Proteins, HeLa Cells, Humans, Hypoxia-Inducible Factor-Proline Dioxygenases, Immediate-Early Proteins, Immunoblotting, Kinesins, Medulloblastoma, Mice, Mice, Knockout, Models, Biological, Mutation, Missense, Nerve Tissue Proteins, Neuroblastoma, Neurons, PC12 Cells, Pheochromocytoma, Procollagen-Proline Dioxygenase, RNA Interference, Rats, Tumor Suppressor Proteins
Added March 5, 2014
0 Communities
1 Members
0 Resources
28 MeSH Terms
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure.
Minamishima YA, Moslehi J, Bardeesy N, Cullen D, Bronson RT, Kaelin WG
(2008) Blood 111: 3236-44
MeSH Terms: Alleles, Animals, Cells, Cultured, DNA-Binding Proteins, Echocardiography, Enzyme Activation, Erythropoiesis, Gene Expression Regulation, Enzymologic, Heart Failure, Hypoxia-Inducible Factor-Proline Dioxygenases, Immediate-Early Proteins, Mice, Mice, Inbred C57BL, Mice, Transgenic, Phenotype, Polycythemia, Procollagen-Proline Dioxygenase, RNA, Messenger
Added March 4, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
Characterization of a putative intrarenal serotonergic system.
Xu J, Yao B, Fan X, Langworthy MM, Zhang MZ, Harris RC
(2007) Am J Physiol Renal Physiol 293: F1468-75
MeSH Terms: Animals, Aromatic-L-Amino-Acid Decarboxylases, Cell Line, Connective Tissue Growth Factor, Immediate-Early Proteins, Immunohistochemistry, In Situ Hybridization, Intercellular Signaling Peptides and Proteins, Kidney Cortex, Kidney Tubules, Proximal, Male, Mice, Mitogen-Activated Protein Kinase Kinases, Phosphorylation, Podocytes, Rats, Rats, Sprague-Dawley, Receptor, Serotonin, 5-HT2A, Receptors, Serotonin, Serotonin, Serotonin Plasma Membrane Transport Proteins, Signal Transduction, Tissue Distribution, Transforming Growth Factor beta, Tryptophan Hydroxylase, Vascular Endothelial Growth Factor A
Added January 28, 2014
1 Communities
2 Members
1 Resources
26 MeSH Terms
Dexamethasone modulates ErbB tyrosine kinase expression and signaling through multiple and redundant mechanisms in cultured rat hepatocytes.
Scheving LA, Buchanan R, Krause MA, Zhang X, Stevenson MC, Russell WE
(2007) Am J Physiol Gastrointest Liver Physiol 293: G552-9
MeSH Terms: Adaptor Proteins, Signal Transducing, Animals, Cell Cycle Proteins, Cell Proliferation, Cells, Cultured, DNA Replication, Dexamethasone, Dose-Response Relationship, Drug, Dual Specificity Phosphatase 1, ErbB Receptors, Glucocorticoids, Hepatocytes, Immediate-Early Proteins, Male, Mitogen-Activated Protein Kinase 1, Mitogen-Activated Protein Kinase 3, Phosphatidylinositol 3-Kinases, Phosphoprotein Phosphatases, Phosphorylation, Protein Phosphatase 1, Protein Tyrosine Phosphatases, Proto-Oncogene Proteins c-akt, Rats, Rats, Sprague-Dawley, Receptor, ErbB-2, Receptor, ErbB-3, SOS1 Protein, Signal Transduction, Time Factors, Transforming Growth Factor alpha
Added March 24, 2014
0 Communities
1 Members
0 Resources
30 MeSH Terms
Aggressive pancreatic ductal adenocarcinoma in mice caused by pancreas-specific blockade of transforming growth factor-beta signaling in cooperation with active Kras expression.
Ijichi H, Chytil A, Gorska AE, Aakre ME, Fujitani Y, Fujitani S, Wright CV, Moses HL
(2006) Genes Dev 20: 3147-60
MeSH Terms: Adenocarcinoma, Aging, Animals, Carcinoma, Pancreatic Ductal, Connective Tissue Growth Factor, Disease Progression, Epithelium, Gene Expression, Genes, ras, Heterozygote, Immediate-Early Proteins, Intercellular Signaling Peptides and Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Mutation, Neoplasm Invasiveness, Pancreas, Pancreatic Neoplasms, Protein Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, Signal Transduction, Stromal Cells, Transcription Factors, Transforming Growth Factor beta, Tumor Cells, Cultured
Added February 17, 2014
2 Communities
2 Members
0 Resources
27 MeSH Terms
Specificity and timing of neocortical transcriptome changes in response to BDNF gene ablation during embryogenesis or adulthood.
Glorioso C, Sabatini M, Unger T, Hashimoto T, Monteggia LM, Lewis DA, Mirnics K
(2006) Mol Psychiatry 11: 633-48
MeSH Terms: Animals, Brain Diseases, Brain-Derived Neurotrophic Factor, Crosses, Genetic, Doxycycline, Gene Expression Profiling, Gene Expression Regulation, Developmental, Genes, Immediate-Early, Humans, Immediate-Early Proteins, Interneurons, Intracellular Signaling Peptides and Proteins, Mice, Mice, Knockout, Nerve Tissue Proteins, Neurons, Neuropeptide Y, Oligonucleotide Array Sequence Analysis, Organ Specificity, Phenotype, Prefrontal Cortex, Recombinant Fusion Proteins, Sequence Deletion, Somatostatin, Time Factors, Transcription, Genetic, gamma-Aminobutyric Acid
Added May 19, 2014
0 Communities
1 Members
0 Resources
27 MeSH Terms
NAD(P)H oxidase 4 mediates transforming growth factor-beta1-induced differentiation of cardiac fibroblasts into myofibroblasts.
Cucoranu I, Clempus R, Dikalova A, Phelan PJ, Ariyan S, Dikalov S, Sorescu D
(2005) Circ Res 97: 900-7
MeSH Terms: Actins, Cell Differentiation, Cells, Cultured, Connective Tissue Growth Factor, Fibroblasts, Fibrosis, Humans, Immediate-Early Proteins, Intercellular Signaling Peptides and Proteins, Myocardium, NADPH Oxidase 4, NADPH Oxidases, RNA, Messenger, Reactive Oxygen Species, Smad2 Protein, Smad3 Protein, Superoxides, Transforming Growth Factor beta, Transforming Growth Factor beta1
Added February 17, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms
Neuronal apoptosis linked to EglN3 prolyl hydroxylase and familial pheochromocytoma genes: developmental culling and cancer.
Lee S, Nakamura E, Yang H, Wei W, Linggi MS, Sajan MP, Farese RV, Freeman RS, Carter BD, Kaelin WG, Schlisio S
(2005) Cancer Cell 8: 155-67
MeSH Terms: Adrenal Gland Neoplasms, Apoptosis, Basic Helix-Loop-Helix Transcription Factors, DNA-Binding Proteins, Dioxygenases, Gene Expression Regulation, Neoplastic, Humans, Hypoxia-Inducible Factor-Proline Dioxygenases, Immediate-Early Proteins, Mutation, Nerve Growth Factor, Neurons, Pheochromocytoma, Procollagen-Proline Dioxygenase, Protein Kinase C, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-jun, Proto-Oncogene Proteins c-ret, Receptor Protein-Tyrosine Kinases, Signal Transduction, Succinate Dehydrogenase, Sympathetic Nervous System, Transcription Factors, Tumor Suppressor Proteins, Ubiquitin-Protein Ligases, Von Hippel-Lindau Tumor Suppressor Protein
Added March 5, 2014
0 Communities
1 Members
0 Resources
26 MeSH Terms