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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 22

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Pharmacological HIF-PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation.
Burmakin M, Fasching A, Kobayashi H, Urrutia AA, Damdimopoulos A, Palm F, Haase VH
(2021) Acta Physiol (Oxf) 233: e13668
MeSH Terms: Animals, Biological Phenomena, Cross-Sectional Studies, Hypoxia-Inducible Factor-Proline Dioxygenases, Nitric Oxide, Prolyl Hydroxylases, Rats, Renal Insufficiency, Chronic
Added April 27, 2021
0 Communities
1 Members
0 Resources
8 MeSH Terms
Inactivation of HIF-prolyl 4-hydroxylases 1, 2 and 3 in NG2-expressing cells induces HIF2-mediated neurovascular expansion independent of erythropoietin.
Urrutia AA, Guan N, Mesa-Ciller C, Afzal A, Davidoff O, Haase VH
(2021) Acta Physiol (Oxf) 231: e13547
MeSH Terms: Animals, Erythropoietin, Hypoxia-Inducible Factor 1, alpha Subunit, Hypoxia-Inducible Factor-Proline Dioxygenases, Mice, Pericytes, Procollagen-Proline Dioxygenase, Prolyl Hydroxylases
Added August 28, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Hypoxia-inducible factor prolyl-4-hydroxylation in FOXD1 lineage cells is essential for normal kidney development.
Kobayashi H, Liu J, Urrutia AA, Burmakin M, Ishii K, Rajan M, Davidoff O, Saifudeen Z, Haase VH
(2017) Kidney Int 92: 1370-1383
MeSH Terms: Anemia, Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Hypoxia, Clinical Trials, Phase III as Topic, Disease Models, Animal, Enzyme Inhibitors, Forkhead Transcription Factors, Humans, Hydroxylation, Hypoxia-Inducible Factor-Proline Dioxygenases, Kidney, Kidney Diseases, Mice, Molecular Targeted Therapy, Mutation, Organ Size, Procollagen-Proline Dioxygenase, Renal Insufficiency, Stromal Cells
Added November 21, 2017
0 Communities
1 Members
0 Resources
20 MeSH Terms
Oxygen sensors as therapeutic targets in kidney disease.
Haase VH
(2017) Nephrol Ther 13 Suppl 1: S29-S34
MeSH Terms: Erythropoietin, Homeostasis, Humans, Hypoxia, Hypoxia-Inducible Factor-Proline Dioxygenases, Kidney, Oxygen, Prolyl-Hydroxylase Inhibitors, Renal Insufficiency, Chronic
Added June 7, 2017
0 Communities
1 Members
0 Resources
9 MeSH Terms
Therapeutic targeting of the HIF oxygen-sensing pathway: Lessons learned from clinical studies.
Haase VH
(2017) Exp Cell Res 356: 160-165
MeSH Terms: Anemia, Animals, Erythropoiesis, Humans, Hypoxia, Hypoxia-Inducible Factor 1, alpha Subunit, Hypoxia-Inducible Factor-Proline Dioxygenases, Oxygen
Added May 10, 2017
0 Communities
1 Members
0 Resources
8 MeSH Terms
HIF-prolyl hydroxylases as therapeutic targets in erythropoiesis and iron metabolism.
Haase VH
(2017) Hemodial Int 21 Suppl 1: S110-S124
MeSH Terms: Anemia, Barbiturates, Clinical Trials as Topic, Erythropoiesis, Erythropoietin, Glycine, Humans, Hypoxia-Inducible Factor-Proline Dioxygenases, Iron, Isoquinolines, Picolinic Acids, Prolyl-Hydroxylase Inhibitors, Renal Dialysis
Added April 28, 2017
0 Communities
1 Members
0 Resources
13 MeSH Terms
Local Delivery of PHD2 siRNA from ROS-Degradable Scaffolds to Promote Diabetic Wound Healing.
Martin JR, Nelson CE, Gupta MK, Yu F, Sarett SM, Hocking KM, Pollins AC, Nanney LB, Davidson JM, Guelcher SA, Duvall CL
(2016) Adv Healthc Mater 5: 2751-2757
MeSH Terms: Animals, Cell Proliferation, Diabetes Mellitus, Hypoxia-Inducible Factor-Proline Dioxygenases, Male, Neovascularization, Physiologic, Procollagen-Proline Dioxygenase, RNA, Small Interfering, Rats, Rats, Sprague-Dawley, Reactive Oxygen Species, Tissue Engineering, Tissue Scaffolds, Wound Healing
Added March 14, 2018
0 Communities
2 Members
0 Resources
14 MeSH Terms
Prolyl-4-hydroxylase 2 and 3 coregulate murine erythropoietin in brain pericytes.
Urrutia AA, Afzal A, Nelson J, Davidoff O, Gross KW, Haase VH
(2016) Blood 128: 2550-2560
MeSH Terms: Animals, Brain, Erythropoietin, Gene Expression Regulation, Hypoxia, Brain, Hypoxia-Inducible Factor-Proline Dioxygenases, Mice, Mice, Transgenic, Pericytes, Procollagen-Proline Dioxygenase, Transcription Factors, Transcription, Genetic
Added September 30, 2016
0 Communities
1 Members
0 Resources
12 MeSH Terms
Vadadustat, a novel oral HIF stabilizer, provides effective anemia treatment in nondialysis-dependent chronic kidney disease.
Pergola PE, Spinowitz BS, Hartman CS, Maroni BJ, Haase VH
(2016) Kidney Int 90: 1115-1122
MeSH Terms: Aged, Anemia, Double-Blind Method, Female, Glycine, Humans, Hypoxia-Inducible Factor-Proline Dioxygenases, Male, Middle Aged, Outcome Assessment, Health Care, Picolinic Acids, Renal Insufficiency, Chronic
Added September 22, 2016
0 Communities
1 Members
0 Resources
12 MeSH Terms
Distinct subpopulations of FOXD1 stroma-derived cells regulate renal erythropoietin.
Kobayashi H, Liu Q, Binns TC, Urrutia AA, Davidoff O, Kapitsinou PP, Pfaff AS, Olauson H, Wernerson A, Fogo AB, Fong GH, Gross KW, Haase VH
(2016) J Clin Invest 126: 1926-38
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Erythropoietin, Forkhead Transcription Factors, Hypoxia, Hypoxia-Inducible Factor-Proline Dioxygenases, Kidney, Mice, Mice, Knockout, Procollagen-Proline Dioxygenase, Stromal Cells
Added May 3, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms