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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 266

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Inhibition of hypoxia-inducible factor-prolyl hydroxylation protects from cyclophosphamide-induced bladder injury and urinary dysfunction.
Clayton DB, Tong CMC, Li B, Taylor AS, De S, Mason MD, Dudley AG, Davidoff O, Kobayashi H, Haase VH
(2022) Am J Physiol Renal Physiol 323: F81-F91
MeSH Terms: Animals, Cyclophosphamide, Disease Models, Animal, Hydroxylation, Hypoxia, Hypoxia-Inducible Factor 1, alpha Subunit, Hypoxia-Inducible Factor-Proline Dioxygenases, Inflammation, Mice, Procollagen-Proline Dioxygenase, Prolyl Hydroxylases, Urinary Bladder
Added May 3, 2022
0 Communities
1 Members
0 Resources
12 MeSH Terms
EPO synthesis induced by HIF-PHD inhibition is dependent on myofibroblast transdifferentiation and colocalizes with non-injured nephron segments in murine kidney fibrosis.
Kobayashi H, Davidoff O, Pujari-Palmer S, Drevin M, Haase VH
(2022) Acta Physiol (Oxf) 235: e13826
MeSH Terms: Animals, Cell Transdifferentiation, Erythropoietin, Fibrosis, Hypoxia-Inducible Factor-Proline Dioxygenases, Kidney, Mice, Mice, Knockout, Myofibroblasts, Nephrons, Prolyl Hydroxylases, Renal Insufficiency, Chronic
Added May 3, 2022
0 Communities
1 Members
0 Resources
12 MeSH Terms
KCNK3 Mutation Causes Altered Immune Function in Pulmonary Arterial Hypertension Patients and Mouse Models.
West JD, Austin ED, Rizzi EM, Yan L, Tanjore H, Crabtree AL, Moore CS, Muthian G, Carrier EJ, Jacobson DA, Hamid R, Kendall PL, Majka S, Rathinasabapathy A
(2021) Int J Mol Sci 22:
MeSH Terms: Animals, Biomarkers, Case-Control Studies, Cytokines, Disease Models, Animal, Disease Susceptibility, Gene Expression Profiling, Genetic Predisposition to Disease, Humans, Hypoxia, Immunomodulation, Lymphocytes, Mice, Mice, Knockout, Models, Biological, Monocytes, Mutation, Nerve Tissue Proteins, Potassium Channels, Tandem Pore Domain, Pulmonary Arterial Hypertension, Transcriptome
Added June 14, 2021
0 Communities
1 Members
0 Resources
21 MeSH Terms
Over-Generalizing About GC (Hypoxia): Pitfalls of Limiting Breadth of Experimental Systems and Analyses in Framing Informatics Conclusions.
Boothby MR, Raybuck A, Cho SH, Stengel KR, Haase VH, Hiebert S, Li J
(2021) Front Immunol 12: 664249
MeSH Terms: Animals, B-Lymphocytes, Biomarkers, Computational Biology, Energy Metabolism, Gene Expression Profiling, Gene Expression Regulation, Germinal Center, Humans, Hypoxia, Immunomodulation, Mice, Transgenic
Added May 28, 2021
0 Communities
1 Members
0 Resources
12 MeSH Terms
Pharmacological HIF-PHD inhibition reduces renovascular resistance and increases glomerular filtration by stimulating nitric oxide generation.
Burmakin M, Fasching A, Kobayashi H, Urrutia AA, Damdimopoulos A, Palm F, Haase VH
(2021) Acta Physiol (Oxf) 233: e13668
MeSH Terms: Animals, Biological Phenomena, Cross-Sectional Studies, Hypoxia-Inducible Factor-Proline Dioxygenases, Nitric Oxide, Prolyl Hydroxylases, Rats, Renal Insufficiency, Chronic
Added April 27, 2021
0 Communities
1 Members
0 Resources
8 MeSH Terms
Stabilization of hypoxia-inducible factor ameliorates glomerular injury sensitization after tubulointerstitial injury.
Zou J, Yang J, Zhu X, Zhong J, Elshaer A, Matsusaka T, Pastan I, Haase VH, Yang HC, Fogo AB
(2021) Kidney Int 99: 620-631
MeSH Terms: Animals, Fibrosis, Hypoxia, Hypoxia-Inducible Factor 1, alpha Subunit, Kidney Diseases, Kidney Glomerulus, Mice, Podocytes
Added November 8, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Inactivation of HIF-prolyl 4-hydroxylases 1, 2 and 3 in NG2-expressing cells induces HIF2-mediated neurovascular expansion independent of erythropoietin.
Urrutia AA, Guan N, Mesa-Ciller C, Afzal A, Davidoff O, Haase VH
(2021) Acta Physiol (Oxf) 231: e13547
MeSH Terms: Animals, Erythropoietin, Hypoxia-Inducible Factor 1, alpha Subunit, Hypoxia-Inducible Factor-Proline Dioxygenases, Mice, Pericytes, Procollagen-Proline Dioxygenase, Prolyl Hydroxylases
Added August 28, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Reverse Cardio-Oncology: Cancer Development in Patients With Cardiovascular Disease.
Aboumsallem JP, Moslehi J, de Boer RA
(2020) J Am Heart Assoc 9: e013754
MeSH Terms: Cardiology, Cardiovascular Diseases, Humans, Incidence, Inflammation, Inflammation Mediators, Medical Oncology, Neoplasms, Prevalence, Prognosis, Risk Assessment, Risk Factors, Signal Transduction, Specialization, Tumor Hypoxia, Tumor Microenvironment
Added May 29, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
The 2019 Nobel Prize honors fundamental discoveries in hypoxia response.
Moslehi J, Rathmell WK
(2020) J Clin Invest 130: 4-6
MeSH Terms: Cell Hypoxia, History, 20th Century, Humans, Hypoxia-Inducible Factor 1, alpha Subunit, Nobel Prize, Vascular Endothelial Growth Factor A, Von Hippel-Lindau Tumor Suppressor Protein
Added November 27, 2019
0 Communities
2 Members
0 Resources
7 MeSH Terms
Hypoxia-inducible factors in CD4 T cells promote metabolism, switch cytokine secretion, and T cell help in humoral immunity.
Cho SH, Raybuck AL, Blagih J, Kemboi E, Haase VH, Jones RG, Boothby MR
(2019) Proc Natl Acad Sci U S A 116: 8975-8984
MeSH Terms: Animals, Antibody Formation, B-Lymphocytes, Basic Helix-Loop-Helix Transcription Factors, CD4-Positive T-Lymphocytes, Cell Hypoxia, Cytokines, Germinal Center, Humans, Hypoxia, Hypoxia-Inducible Factor 1, alpha Subunit, Immunity, Humoral, Immunization, Lymphocyte Activation, Mice, Mice, Inbred C57BL, Mice, Transgenic, Receptors, CXCR5, Sheep, T-Lymphocytes, Helper-Inducer
Added April 23, 2019
0 Communities
1 Members
0 Resources
20 MeSH Terms