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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 73

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Importance of the route of insulin delivery to its control of glucose metabolism.
Edgerton DS, Moore MC, Gregory JM, Kraft G, Cherrington AD
(2021) Am J Physiol Endocrinol Metab 320: E891-E897
MeSH Terms: Blood Glucose, Drug Administration Routes, Gluconeogenesis, Glucose, Glycemic Control, Humans, Hyperinsulinism, Hypoglycemia, Insulin, Insulin Infusion Systems, Insulin Secretion, Liver
Added May 19, 2021
0 Communities
2 Members
0 Resources
12 MeSH Terms
Iatrogenic Hyperinsulinemia, Not Hyperglycemia, Drives Insulin Resistance in Type 1 Diabetes as Revealed by Comparison With GCK-MODY (MODY2).
Gregory JM, Smith TJ, Slaughter JC, Mason HR, Hughey CC, Smith MS, Kandasamy B, Greeley SAW, Philipson LH, Naylor RN, Letourneau LR, Abumrad NN, Cherrington AD, Moore DJ
(2019) Diabetes 68: 1565-1576
MeSH Terms: Adolescent, Adult, Diabetes Mellitus, Type 2, Female, Humans, Hyperglycemia, Hyperinsulinism, Insulin Resistance, Male, Middle Aged, Models, Theoretical, Young Adult
Added May 17, 2019
0 Communities
2 Members
0 Resources
12 MeSH Terms
Targeting insulin to the liver corrects defects in glucose metabolism caused by peripheral insulin delivery.
Edgerton DS, Scott M, Farmer B, Williams PE, Madsen P, Kjeldsen T, Brand CL, Fledelius C, Nishimura E, Cherrington AD
(2019) JCI Insight 5:
MeSH Terms: Animals, Dogs, Glucose, Glucose Clamp Technique, Hindlimb, Hyperglycemia, Hyperinsulinism, Hypoglycemic Agents, Insulin, Liver, Muscle, Skeletal, Portal Vein, Veins
Added November 9, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Androgen excess in pancreatic β cells and neurons predisposes female mice to type 2 diabetes.
Navarro G, Allard C, Morford JJ, Xu W, Liu S, Molinas AJ, Butcher SM, Fine NH, Blandino-Rosano M, Sure VN, Yu S, Zhang R, Münzberg H, Jacobson DA, Katakam PV, Hodson DJ, Bernal-Mizrachi E, Zsombok A, Mauvais-Jarvis F
(2018) JCI Insight 3:
MeSH Terms: Androgens, Animals, Diabetes Mellitus, Type 2, Diet, Western, Dihydrotestosterone, Female, Glucose, Humans, Hyperinsulinism, Hypothalamus, Insulin Resistance, Insulin-Secreting Cells, Mice, Mice, Inbred C57BL, Mice, Knockout, Mitochondria, Neurons, Receptors, Androgen, Streptozocin
Added June 28, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
Insulin exits skeletal muscle capillaries by fluid-phase transport.
Williams IM, Valenzuela FA, Kahl SD, Ramkrishna D, Mezo AR, Young JD, Wells KS, Wasserman DH
(2018) J Clin Invest 128: 699-714
MeSH Terms: Animals, Antigens, CD, Biological Transport, Capillaries, Diabetes Mellitus, Glucose, Glucose Clamp Technique, Humans, Hyperinsulinism, Image Processing, Computer-Assisted, Insulin, Intravital Microscopy, Kinetics, Male, Mice, Mice, Inbred C57BL, Models, Theoretical, Muscle, Skeletal, Protein Binding, Receptor, Insulin, Rhodamines
Added March 14, 2018
1 Communities
1 Members
0 Resources
21 MeSH Terms
Hyperinsulinemia and Insulin Resistance in Dopamine β-Hydroxylase Deficiency.
Arnold AC, Garland EM, Celedonio JE, Raj SR, Abumrad NN, Biaggioni I, Robertson D, Luther JM, Shibao CA
(2017) J Clin Endocrinol Metab 102: 10-14
MeSH Terms: Adolescent, Animals, Autonomic Nervous System Diseases, Dopamine beta-Hydroxylase, Droxidopa, Female, Humans, Hyperinsulinism, Insulin, Insulin Resistance, Mice, Norepinephrine, Prognosis
Added March 14, 2018
0 Communities
2 Members
0 Resources
13 MeSH Terms
Acute effects of hyperinsulinemia and hyperglycemia on vascular inflammatory biomarkers and endothelial function in overweight and obese humans.
Perkins JM, Joy NG, Tate DB, Davis SN
(2015) Am J Physiol Endocrinol Metab 309: E168-76
MeSH Terms: Adult, Biomarkers, Blood Glucose, Endothelium, Vascular, Female, Glucose Clamp Technique, Humans, Hyperglycemia, Hyperinsulinism, Inflammation Mediators, Insulin, Male, Obesity, Overweight, Vasculitis
Added July 30, 2015
0 Communities
0 Members
2 Resources
15 MeSH Terms
Is brain insulin action relevant to the control of plasma glucose in humans?
Edgerton DS, Cherrington AD
(2015) Diabetes 64: 696-9
MeSH Terms: Female, Glucose, Humans, Hyperinsulinism, Hypoglycemic Agents, Insulin, Male
Added July 30, 2015
0 Communities
1 Members
0 Resources
7 MeSH Terms
Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.
Ueta K, O'Brien TP, McCoy GA, Kim K, Healey EC, Farmer TD, Donahue EP, Condren AB, Printz RL, Shiota M
(2014) Am J Physiol Endocrinol Metab 306: E1225-38
MeSH Terms: Animals, Body Weight, Canagliflozin, Diabetes Mellitus, Type 2, Eating, Glucagon, Glucokinase, Glucose, Glucose Clamp Technique, Glucosides, Hyperglycemia, Hyperinsulinism, Immunohistochemistry, Liver, Male, Obesity, Organ Size, Oxygen Consumption, RNA, Messenger, Rats, Rats, Zucker, Sodium-Glucose Transporter 2, Sodium-Glucose Transporter 2 Inhibitors, Thiophenes
Added February 19, 2015
0 Communities
1 Members
0 Resources
24 MeSH Terms
Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells.
Tornovsky-Babeay S, Dadon D, Ziv O, Tzipilevich E, Kadosh T, Schyr-Ben Haroush R, Hija A, Stolovich-Rain M, Furth-Lavi J, Granot Z, Porat S, Philipson LH, Herold KC, Bhatti TR, Stanley C, Ashcroft FM, In't Veld P, Saada A, Magnuson MA, Glaser B, Dor Y
(2014) Cell Metab 19: 109-21
MeSH Terms: Animals, Biomarkers, Calcineurin, Cell Death, Cell Proliferation, Congenital Hyperinsulinism, DNA Breaks, Double-Stranded, Diabetes Mellitus, Type 2, Disease Models, Animal, Enzyme Activation, Enzyme Induction, Fasting, Glucagon-Like Peptide 1, Glucokinase, Glucose, Humans, Insulin-Secreting Cells, Membrane Potentials, Mice, Transgenes, Tumor Suppressor Protein p53
Added February 11, 2014
2 Communities
1 Members
1 Resources
21 MeSH Terms