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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 6 of 6

Publication Record


Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.
Bryan MR, Bowman AB
(2017) Adv Neurobiol 18: 113-142
MeSH Terms: Alzheimer Disease, Amyotrophic Lateral Sclerosis, Animals, Autophagy, Brain, Disease Models, Animal, Humans, Huntingtin Protein, Huntington Disease, Insulin, Manganese, Mitochondria, Neostriatum, Neural Stem Cells, Neurodegenerative Diseases, Parkinson Disease, Reactive Oxygen Species, Signal Transduction, Somatomedins
Added April 11, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Embryonic Mutant Huntingtin Aggregate Formation in Mouse Models of Huntington's Disease.
Osmand AP, Bichell TJ, Bowman AB, Bates GP
(2016) J Huntingtons Dis 5: 343-346
MeSH Terms: Animals, Axons, Brain, Disease Models, Animal, Huntingtin Protein, Huntington Disease, Immunohistochemistry, Mice, Transgenic, Protein Aggregation, Pathological
Added April 26, 2017
0 Communities
1 Members
0 Resources
9 MeSH Terms
BDNF and Huntingtin protein modifications by manganese: implications for striatal medium spiny neuron pathology in manganese neurotoxicity.
Stansfield KH, Bichell TJ, Bowman AB, Guilarte TR
(2014) J Neurochem 131: 655-66
MeSH Terms: Animals, Brain, Brain-Derived Neurotrophic Factor, Cells, Cultured, Cerebral Cortex, Corpus Striatum, Dendritic Spines, Disease Models, Animal, Dose-Response Relationship, Drug, Embryo, Mammalian, Gene Expression Regulation, Huntingtin Protein, Manganese, Manganese Poisoning, Mice, Microtubule-Associated Proteins, Nerve Tissue Proteins, Neurons, Nuclear Proteins, Phosphorylation, Rats, Rats, Sprague-Dawley
Added February 15, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms
Changes in the striatal proteome of YAC128Q mice exhibit gene-environment interactions between mutant huntingtin and manganese.
Wegrzynowicz M, Holt HK, Friedman DB, Bowman AB
(2012) J Proteome Res 11: 1118-32
MeSH Terms: Analysis of Variance, Animals, Blotting, Western, Electrophoresis, Gel, Two-Dimensional, Gene-Environment Interaction, Huntingtin Protein, Male, Manganese, Mice, Mice, Transgenic, Neostriatum, Nerve Tissue Proteins, Nuclear Proteins, Principal Component Analysis, Proteome, Proteomics
Added May 19, 2014
1 Communities
1 Members
0 Resources
16 MeSH Terms
Altered manganese homeostasis and manganese toxicity in a Huntington's disease striatal cell model are not explained by defects in the iron transport system.
Williams BB, Kwakye GF, Wegrzynowicz M, Li D, Aschner M, Erikson KM, Bowman AB
(2010) Toxicol Sci 117: 169-79
MeSH Terms: Animals, Biological Transport, Cation Transport Proteins, Corpus Striatum, Disease Models, Animal, Homeostasis, Humans, Huntingtin Protein, Huntington Disease, Iron, Manganese, Mice, Nerve Tissue Proteins, Nuclear Proteins
Added February 3, 2011
1 Communities
1 Members
0 Resources
14 MeSH Terms
Disease-toxicant screen reveals a neuroprotective interaction between Huntington's disease and manganese exposure.
Williams BB, Li D, Wegrzynowicz M, Vadodaria BK, Anderson JG, Kwakye GF, Aschner M, Erikson KM, Bowman AB
(2010) J Neurochem 112: 227-37
MeSH Terms: Animals, Cattle, Cell Line, Cell Survival, Drug Evaluation, Preclinical, Humans, Huntingtin Protein, Huntington Disease, Manganese, Mice, Mice, Transgenic, Nerve Tissue Proteins, Nuclear Proteins
Added June 9, 2010
1 Communities
1 Members
0 Resources
13 MeSH Terms