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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 6 of 6

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Transcription factor ETV1 is essential for rapid conduction in the heart.
Shekhar A, Lin X, Liu FY, Zhang J, Mo H, Bastarache L, Denny JC, Cox NJ, Delmar M, Roden DM, Fishman GI, Park DS
(2016) J Clin Invest 126: 4444-4459
MeSH Terms: Animals, DNA-Binding Proteins, Heart Atria, Heart Conduction System, Heart Ventricles, Homeobox Protein Nkx-2.5, Humans, Mice, Mice, Transgenic, Myocardium, Myocytes, Cardiac, NAV1.5 Voltage-Gated Sodium Channel, Transcription Factors
Added March 14, 2018
0 Communities
2 Members
0 Resources
13 MeSH Terms
Nkx genes are essential for maintenance of ventricular identity.
Targoff KL, Colombo S, George V, Schell T, Kim SH, Solnica-Krezel L, Yelon D
(2013) Development 140: 4203-13
MeSH Terms: Animals, Atrial Myosins, Cell Differentiation, Cell Proliferation, Gene Expression Regulation, Developmental, Genotype, Heart Atria, Heart Ventricles, Homeobox Protein Nkx-2.5, Homeodomain Proteins, Mutation, Myocytes, Cardiac, Transcription Factors, Transcription, Genetic, Ventricular Myosins, Zebrafish, Zebrafish Proteins
Added September 24, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Proliferation of embryonic cardiomyocytes in zebrafish requires the sodium channel scn5Lab.
Bennett JS, Stroud DM, Becker JR, Roden DM
(2013) Genesis 51: 562-74
MeSH Terms: Animals, Cell Differentiation, Cell Proliferation, Heart, Homeobox Protein Nkx-2.5, Morphogenesis, Morpholinos, Myocytes, Cardiac, NAV1.5 Voltage-Gated Sodium Channel, Transcription Factors, Zebrafish, Zebrafish Proteins
Added July 21, 2014
1 Communities
1 Members
0 Resources
12 MeSH Terms
Chromosome 4q25 variants are genetic modifiers of rare ion channel mutations associated with familial atrial fibrillation.
Ritchie MD, Rowan S, Kucera G, Stubblefield T, Blair M, Carter S, Roden DM, Darbar D
(2012) J Am Coll Cardiol 60: 1173-81
MeSH Terms: Adult, Aged, Atrial Fibrillation, Atrial Natriuretic Factor, Chromosomes, Human, Pair 4, Cohort Studies, Genetic Predisposition to Disease, Genotype, Homeobox Protein Nkx-2.5, Homeodomain Proteins, Humans, Ion Channels, KCNQ1 Potassium Channel, Kv1.5 Potassium Channel, Middle Aged, Mutation, NAV1.5 Voltage-Gated Sodium Channel, Pedigree, Polymorphism, Single Nucleotide, Prospective Studies, Registries, Transcription Factors
Added June 26, 2014
0 Communities
1 Members
0 Resources
22 MeSH Terms
Voltage-gated sodium channels are required for heart development in zebrafish.
Chopra SS, Stroud DM, Watanabe H, Bennett JS, Burns CG, Wells KS, Yang T, Zhong TP, Roden DM
(2010) Circ Res 106: 1342-50
MeSH Terms: Age Factors, Amino Acid Sequence, Animals, Animals, Genetically Modified, Basic Helix-Loop-Helix Transcription Factors, CHO Cells, Cell Differentiation, Cricetinae, Cricetulus, GATA Transcription Factors, Gastrulation, Gene Expression Regulation, Developmental, Gene Knockdown Techniques, Genotype, Heart, Heart Defects, Congenital, Homeobox Protein Nkx-2.5, Membrane Potentials, Molecular Sequence Data, Morphogenesis, Myocardium, NAV1.5 Voltage-Gated Sodium Channel, Oligonucleotides, Antisense, Phenotype, RNA, Messenger, Sodium Channels, Transcription Factors, Transfection, Zebrafish, Zebrafish Proteins
Added January 17, 2014
0 Communities
2 Members
0 Resources
30 MeSH Terms
RNA-binding protein Csx1 mediates global control of gene expression in response to oxidative stress.
Rodríguez-Gabriel MA, Burns G, McDonald WH, Martín V, Yates JR, Bähler J, Russell P
(2003) EMBO J 22: 6256-66
MeSH Terms: Fungal Proteins, Gene Expression Regulation, Homeobox Protein Nkx-2.5, Homeodomain Proteins, Mutagenesis, Insertional, Oligonucleotide Array Sequence Analysis, Oxidative Stress, Phosphorylation, RNA, Messenger, RNA-Binding Proteins, Recombinant Proteins, Schizosaccharomyces, Transcription Factors
Added March 20, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms