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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 48

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Histone deacetylase 3 controls a transcriptional network required for B cell maturation.
Stengel KR, Bhaskara S, Wang J, Liu Q, Ellis JD, Sampathi S, Hiebert SW
(2019) Nucleic Acids Res 47: 10612-10627
MeSH Terms: Animals, Antigens, CD19, B-Lymphocytes, Base Sequence, Cell Differentiation, Gene Expression Regulation, Gene Regulatory Networks, Histone Deacetylase Inhibitors, Histone Deacetylases, Lipopolysaccharides, Lymphocyte Activation, Mice, Inbred C57BL, Plasma Cells, Positive Regulatory Domain I-Binding Factor 1, Proto-Oncogene Proteins c-bcl-6, Repressor Proteins, Transcription, Genetic, Up-Regulation
Added October 25, 2019
1 Communities
0 Members
0 Resources
18 MeSH Terms
HDAC11 suppresses the thermogenic program of adipose tissue via BRD2.
Bagchi RA, Ferguson BS, Stratton MS, Hu T, Cavasin MA, Sun L, Lin YH, Liu D, Londono P, Song K, Pino MF, Sparks LM, Smith SR, Scherer PE, Collins S, Seto E, McKinsey TA
(2018) JCI Insight 3:
MeSH Terms: Adipose Tissue, Brown, Adipose Tissue, White, Adult, Aged, Aged, 80 and over, Animals, Diet, High-Fat, Disease Models, Animal, Energy Metabolism, Epigenesis, Genetic, Fatty Liver, Female, Gene Expression Regulation, Histone Deacetylases, Humans, Insulin Resistance, Male, Mice, Mice, Knockout, Middle Aged, Obesity, Thermogenesis, Transcription Factors
Added July 22, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
HDAC3 is a molecular brake of the metabolic switch supporting white adipose tissue browning.
Ferrari A, Longo R, Fiorino E, Silva R, Mitro N, Cermenati G, Gilardi F, Desvergne B, Andolfo A, Magagnotti C, Caruso D, Fabiani E, Hiebert SW, Crestani M
(2017) Nat Commun 8: 93
MeSH Terms: Adipocytes, Adipose Tissue, Brown, Adipose Tissue, White, Animals, Cell Line, Diet, High-Fat, Gene Expression Regulation, Gene Silencing, Histone Deacetylases, Lipid Metabolism, Male, Mice, Mice, Knockout
Added February 7, 2019
1 Communities
0 Members
0 Resources
MeSH Terms
Imbalance between HDAC and HAT activities drives aberrant STAT1/MyD88 expression in macrophages from type 1 diabetic mice.
Filgueiras LR, Brandt SL, Ramalho TR, Jancar S, Serezani CH
(2017) J Diabetes Complications 31: 334-339
MeSH Terms: Acetylation, Animals, Bone Marrow Cells, Cells, Cultured, Diabetes Mellitus, Type 1, Enzyme Inhibitors, Epigenesis, Genetic, Gene Expression Regulation, Glucose, Histone Acetyltransferases, Histone Deacetylases, Histones, Macrophages, Macrophages, Peritoneal, Male, Mice, Inbred C57BL, Myeloid Differentiation Factor 88, Osmolar Concentration, Promoter Regions, Genetic, Protein Processing, Post-Translational, STAT1 Transcription Factor, Streptozocin
Added May 4, 2017
0 Communities
1 Members
0 Resources
22 MeSH Terms
Histone Deacetylase 3 Is Required for Efficient T Cell Development.
Stengel KR, Zhao Y, Klus NJ, Kaiser JF, Gordy LE, Joyce S, Hiebert SW, Summers AR
(2015) Mol Cell Biol 35: 3854-65
MeSH Terms: Animals, CD4 Antigens, CD4-Positive T-Lymphocytes, CD8 Antigens, CD8-Positive T-Lymphocytes, Cell Differentiation, Gene Deletion, Gene Expression Regulation, Developmental, Histone Deacetylases, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Proto-Oncogene Proteins c-bcl-2, Receptors, Antigen, T-Cell, alpha-beta, T-Lymphocytes, bcl-X Protein
Added September 28, 2015
1 Communities
2 Members
0 Resources
18 MeSH Terms
Histone Deacetylase 3 Is Required for T Cell Maturation.
Hsu FC, Belmonte PJ, Constans MM, Chen MW, McWilliams DC, Hiebert SW, Shapiro VS
(2015) J Immunol 195: 1578-90
MeSH Terms: Animals, Bone Marrow Cells, Cell Differentiation, Cell Movement, Complement Activation, Complement System Proteins, Histone Deacetylases, Homeostasis, Interleukin-7, Lymphocyte Count, Mice, Mice, Knockout, Mice, Transgenic, T-Lymphocyte Subsets, T-Lymphocytes, Thymus Gland, Tumor Necrosis Factors
Added September 28, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells.
Koumangoye RB, Andl T, Taubenslag KJ, Zilberman ST, Taylor CJ, Loomans HA, Andl CD
(2015) Mol Cancer 14: 24
MeSH Terms: 3' Untranslated Regions, Base Sequence, Binding Sites, Cell Line, Tumor, Down-Regulation, Enhancer of Zeste Homolog 2 Protein, Epigenesis, Genetic, Esophageal Neoplasms, Gene Expression Regulation, Neoplastic, Histone Deacetylases, Humans, MicroRNAs, Neoplasm Invasiveness, Polycomb Repressive Complex 2, Protein Binding, RNA Interference, Repressor Proteins, SOXC Transcription Factors
Added October 13, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
FOXP3+ regulatory T cell development and function require histone/protein deacetylase 3.
Wang L, Liu Y, Han R, Beier UH, Bhatti TR, Akimova T, Greene MI, Hiebert SW, Hancock WW
(2015) J Clin Invest 125: 1111-23
MeSH Terms: Animals, Autoimmunity, Cells, Cultured, Forkhead Transcription Factors, Gene Expression Regulation, HEK293 Cells, Histone Deacetylases, Humans, Interleukin-2, Lymphocyte Activation, Male, Mice, Inbred BALB C, Mice, Inbred C57BL, Mice, Knockout, T-Lymphocytes, Regulatory
Added September 28, 2015
0 Communities
1 Members
0 Resources
15 MeSH Terms
A Phase I Study of CUDC-101, a Multitarget Inhibitor of HDACs, EGFR, and HER2, in Combination with Chemoradiation in Patients with Head and Neck Squamous Cell Carcinoma.
Galloway TJ, Wirth LJ, Colevas AD, Gilbert J, Bauman JE, Saba NF, Raben D, Mehra R, Ma AW, Atoyan R, Wang J, Burtness B, Jimeno A
(2015) Clin Cancer Res 21: 1566-73
MeSH Terms: Aged, Antineoplastic Agents, Carcinoma, Squamous Cell, Chemoradiotherapy, Cisplatin, ErbB Receptors, Female, Head and Neck Neoplasms, Histone Deacetylases, Humans, Hydroxamic Acids, Male, Maximum Tolerated Dose, Middle Aged, Quinazolines, Radiotherapy, Receptor, ErbB-2, Squamous Cell Carcinoma of Head and Neck
Added February 17, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
HDAC3 is essential for DNA replication in hematopoietic progenitor cells.
Summers AR, Fischer MA, Stengel KR, Zhao Y, Kaiser JF, Wells CE, Hunt A, Bhaskara S, Luzwick JW, Sampathi S, Chen X, Thompson MA, Cortez D, Hiebert SW
(2013) J Clin Invest 123: 3112-23
MeSH Terms: Animals, Bone Marrow Cells, Bone Marrow Transplantation, Cell Differentiation, Cell Proliferation, Cells, Cultured, DNA Replication, Hematopoietic Stem Cells, Histone Deacetylases, Lymphopoiesis, Mice, Mice, Inbred C57BL, Mice, Knockout, S Phase, Spleen, Transcriptome
Added March 5, 2014
2 Communities
4 Members
0 Resources
16 MeSH Terms