Histone deacetylase 3 controls a transcriptional network required for B cell maturation.
Stengel KR, Bhaskara S, Wang J, Liu Q, Ellis JD, Sampathi S, Hiebert SW
(2019) Nucleic Acids Res 47
: 10612-10627MeSH Terms: Animals, Antigens, CD19, B-Lymphocytes, Base Sequence, Cell Differentiation, Gene Expression Regulation, Gene Regulatory Networks, Histone Deacetylase Inhibitors, Histone Deacetylases, Lipopolysaccharides, Lymphocyte Activation, Mice, Inbred C57BL, Plasma Cells, Positive Regulatory Domain I-Binding Factor 1, Proto-Oncogene Proteins c-bcl-6, Repressor Proteins, Transcription, Genetic, Up-RegulationAdded October 25, 2019
18 MeSH Terms
Sepsis-Associated Acute Kidney Injury: A Problem Deserving of New Solutions.
Kellum JA, Wen X, de Caestecker MP, Hukriede NA
(2019) Nephron 143
: 174-178MeSH Terms: Acute Kidney Injury, Animals, Histone Deacetylase Inhibitors, Humans, Kidney, Regeneration, SepsisAdded May 10, 2020
7 MeSH Terms
Epigenetic (re)programming of caste-specific behavior in the ant Camponotus floridanus.
Simola DF, Graham RJ, Brady CM, Enzmann BL, Desplan C, Ray A, Zwiebel LJ, Bonasio R, Reinberg D, Liebig J, Berger SL
(2016) Science 351
: aac6633MeSH Terms: Acetylation, Animals, Ants, Behavior, Animal, Chromatin, Epigenesis, Genetic, Histone Deacetylase 2, Histone Deacetylase Inhibitors, Protein Processing, Post-Translational, Social Behavior, Social Class, TranscriptomeAdded February 15, 2016
12 MeSH Terms
Myc Induces miRNA-Mediated Apoptosis in Response to HDAC Inhibition in Hematologic Malignancies.
Adams CM, Hiebert SW, Eischen CM
(2016) Cancer Res 76
: 736-48MeSH Terms: Animals, Apoptosis, Cell Line, Tumor, Hematologic Neoplasms, Histone Deacetylase Inhibitors, Humans, Mice, Inbred C57BL, MicroRNAs, Proto-Oncogene Proteins c-myc, TransfectionAdded February 4, 2016
10 MeSH Terms
Histone deacetylase inhibitor treatment induces 'BRCAness' and synergistic lethality with PARP inhibitor and cisplatin against human triple negative breast cancer cells.
Ha K, Fiskus W, Choi DS, Bhaskara S, Cerchietti L, Devaraj SG, Shah B, Sharma S, Chang JC, Melnick AM, Hiebert S, Bhalla KN
(2014) Oncotarget 5
: 5637-50MeSH Terms: Animals, Antineoplastic Combined Chemotherapy Protocols, Apoptosis, Ataxia Telangiectasia Mutated Proteins, BRCA1 Protein, Cell Line, Tumor, Checkpoint Kinase 1, Cisplatin, DNA Damage, Drug Synergism, Enzyme Inhibitors, Female, Gene Knockdown Techniques, HSP90 Heat-Shock Proteins, HeLa Cells, Histone Deacetylase Inhibitors, Humans, Hydroxamic Acids, Indoles, MCF-7 Cells, Mice, Panobinostat, Poly(ADP-ribose) Polymerase Inhibitors, Protein Kinases, Reactive Oxygen Species, Triple Negative Breast Neoplasms, Vorinostat, Xenograft Model Antitumor AssaysAdded September 28, 2015
28 MeSH Terms
Suberoylanilide hydroxamic acid (SAHA) enhances olaparib activity by targeting homologous recombination DNA repair in ovarian cancer.
Konstantinopoulos PA, Wilson AJ, Saskowski J, Wass E, Khabele D
(2014) Gynecol Oncol 133
: 599-606MeSH Terms: Animals, Antineoplastic Agents, Carcinoma, Ovarian Epithelial, Cell Line, Tumor, Cell Proliferation, Cell Survival, DNA Damage, DNA, Neoplasm, Down-Regulation, Drug Resistance, Neoplasm, Drug Synergism, Female, Histone Deacetylase Inhibitors, Humans, Hydroxamic Acids, Mice, Mice, Nude, Neoplasms, Glandular and Epithelial, Ovarian Neoplasms, Phthalazines, Piperazines, Recombinational DNA Repair, Tissue Array Analysis, Vorinostat, Xenograft Model Antitumor AssaysAdded March 28, 2014
25 MeSH Terms
A PTBA small molecule enhances recovery and reduces postinjury fibrosis after aristolochic acid-induced kidney injury.
Novitskaya T, McDermott L, Zhang KX, Chiba T, Paueksakon P, Hukriede NA, de Caestecker MP
(2014) Am J Physiol Renal Physiol 306
: F496-504MeSH Terms: Acute Kidney Injury, Animals, Aristolochic Acids, Butyrates, Disease Models, Animal, Fibrosis, Histone Deacetylase Inhibitors, Kidney Tubules, Mice, Mice, Biozzi, Reperfusion Injury, SulfidesAdded March 20, 2014
12 MeSH Terms
Inhibition of histone deacetylase 3 causes replication stress in cutaneous T cell lymphoma.
Wells CE, Bhaskara S, Stengel KR, Zhao Y, Sirbu B, Chagot B, Cortez D, Khabele D, Chazin WJ, Cooper A, Jacques V, Rusche J, Eischen CM, McGirt LY, Hiebert SW
(2013) PLoS One 8
: e68915MeSH Terms: Antineoplastic Agents, Apoptosis, Cell Line, Tumor, Cell Proliferation, Chromatin, DNA Damage, DNA Replication, Drug Synergism, Histone Deacetylase Inhibitors, Histone Deacetylases, Humans, Lymphoma, T-Cell, Cutaneous, S Phase, Stress, PhysiologicalAdded September 5, 2013
14 MeSH Terms
Trichostatin-A modulates claudin-1 mRNA stability through the modulation of Hu antigen R and tristetraprolin in colon cancer cells.
Sharma A, Bhat AA, Krishnan M, Singh AB, Dhawan P
(2013) Carcinogenesis 34
: 2610-21MeSH Terms: 3' Untranslated Regions, Base Sequence, Blotting, Western, Breast Neoplasms, Cells, Cultured, Chromatin Immunoprecipitation, Claudin-1, Colonic Neoplasms, ELAV Proteins, Epigenesis, Genetic, Female, Fluorescent Antibody Technique, Gene Expression Regulation, Neoplastic, Histone Deacetylase Inhibitors, Humans, Hydroxamic Acids, Immunoenzyme Techniques, Kidney, Molecular Sequence Data, Mutagenesis, Site-Directed, RNA, Messenger, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, TristetraprolinAdded March 7, 2014
24 MeSH Terms
Histone deacetylase inhibitor enhances recovery after AKI.
Cianciolo Cosentino C, Skrypnyk NI, Brilli LL, Chiba T, Novitskaya T, Woods C, West J, Korotchenko VN, McDermott L, Day BW, Davidson AJ, Harris RC, de Caestecker MP, Hukriede NA
(2013) J Am Soc Nephrol 24
: 943-53MeSH Terms: Acute Kidney Injury, Animals, Disease Models, Animal, Fibrosis, Gentamicins, Histone Deacetylase 1, Histone Deacetylase Inhibitors, Ischemia, Kidney, Male, Mice, Mice, Inbred BALB C, Phenylbutyrates, Protein Synthesis Inhibitors, Recovery of Function, Zebrafish, Zebrafish ProteinsAdded February 10, 2014
17 MeSH Terms