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Results: 1 to 6 of 6

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ERAAP and tapasin independently edit the amino and carboxyl termini of MHC class I peptides.
Kanaseki T, Lind KC, Escobar H, Nagarajan N, Reyes-Vargas E, Rudd B, Rockwood AL, Van Kaer L, Sato N, Delgado JC, Shastri N
(2013) J Immunol 191: 1547-55
MeSH Terms: Amino Acid Motifs, Amino Acid Sequence, Animals, Antigen Presentation, CD8-Positive T-Lymphocytes, Cells, Cultured, Consensus Sequence, Cytotoxicity, Immunologic, Endoplasmic Reticulum, Epitopes, T-Lymphocyte, Female, H-2 Antigens, Histocompatibility Antigen H-2D, Histocompatibility Antigens Class I, Leucyl Aminopeptidase, Membrane Transport Proteins, Mice, Mice, Inbred C57BL, Molecular Sequence Data, Peptide Fragments, Proteasome Endopeptidase Complex
Added March 7, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Pivotal roles of CD8+ T cells restricted by MHC class I-like molecules in autoimmune diseases.
Das G, Das J, Eynott P, Zhang Y, Bothwell AL, Van Kaer L, Shi Y
(2006) J Exp Med 203: 2603-11
MeSH Terms: Animals, Autoimmune Diseases, CD8-Positive T-Lymphocytes, Cell Survival, Female, H-2 Antigens, Histocompatibility Antigen H-2D, Histocompatibility Antigens Class II, Inflammatory Bowel Diseases, Islets of Langerhans, Lymphoproliferative Disorders, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Nuclear Proteins, Trans-Activators, beta 2-Microglobulin
Added December 10, 2013
0 Communities
1 Members
0 Resources
19 MeSH Terms
Hepatocytes express abundant surface class I MHC and efficiently use transporter associated with antigen processing, tapasin, and low molecular weight polypeptide proteasome subunit components of antigen processing and presentation pathway.
Chen M, Tabaczewski P, Truscott SM, Van Kaer L, Stroynowski I
(2005) J Immunol 175: 1047-55
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP Binding Cassette Transporter, Subfamily B, Member 3, ATP-Binding Cassette Transporters, Animals, Antigen Presentation, Antiporters, Cell Membrane, Cells, Cultured, Cysteine Endopeptidases, Gene Expression Regulation, H-2 Antigens, Hepatocytes, Histocompatibility Antigen H-2D, Immunoglobulins, Listeriosis, Male, Membrane Transport Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, Multienzyme Complexes, Proteasome Endopeptidase Complex, Protein Processing, Post-Translational, Protein Subunits, Signal Transduction, Spleen
Added December 10, 2013
0 Communities
1 Members
0 Resources
26 MeSH Terms
Identification of an H-2D(b)-restricted CD8+ cytotoxic T lymphocyte epitope in the matrix protein of respiratory syncytial virus.
Rutigliano JA, Rock MT, Johnson AK, Crowe JE, Graham BS
(2005) Virology 337: 335-43
MeSH Terms: Amino Acid Sequence, Animals, Cell Line, Tumor, Cytokines, Disease Models, Animal, Epitopes, Female, H-2 Antigens, Histocompatibility Antigen H-2D, Humans, Major Histocompatibility Complex, Mice, Mice, Inbred BALB C, Molecular Sequence Data, Peptide Fragments, Respiratory Syncytial Virus Infections, Respiratory Syncytial Viruses, T-Lymphocytes, Cytotoxic, Viral Matrix Proteins
Added August 6, 2012
0 Communities
1 Members
0 Resources
19 MeSH Terms
Tapasin enhances peptide-induced expression of H2-M3 molecules, but is not required for the retention of open conformers.
Lybarger L, Yu YY, Chun T, Wang CR, Grandea AG, Van Kaer L, Hansen TH
(2001) J Immunol 167: 2097-105
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 2, ATP Binding Cassette Transporter, Subfamily B, Member 3, ATP-Binding Cassette Transporters, Adjuvants, Immunologic, Animals, Antiporters, Cell Line, Transformed, Epitopes, H-2 Antigens, HeLa Cells, Histocompatibility Antigen H-2D, Histocompatibility Antigens Class I, Humans, Immunoglobulins, L Cells, Membrane Transport Proteins, Mice, Mutagenesis, Site-Directed, Peptides, Protein Binding, Protein Conformation, Transfection
Added December 10, 2013
1 Communities
1 Members
0 Resources
22 MeSH Terms
Traffic control of completely assembled MHC class I molecules beyond the endoplasmic reticulum.
Joyce S
(1997) J Mol Biol 266: 993-1001
MeSH Terms: Amino Acid Sequence, Antigen Presentation, Biological Transport, Cell Compartmentation, Cell Membrane, Endoplasmic Reticulum, Exocytosis, Flow Cytometry, Glycoproteins, Golgi Apparatus, H-2 Antigens, Histocompatibility Antigen H-2D, Histocompatibility Antigens Class I, Protein Binding, Recombinant Proteins, Sequence Analysis, Sindbis Virus, Viral Structural Proteins, beta 2-Microglobulin
Added October 2, 2015
0 Communities
1 Members
0 Resources
19 MeSH Terms