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Results: 1 to 10 of 12

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Histamine elevates free intracellular calcium in mouse retinal dopaminergic cells via H1-receptors.
Fraz√£o R, McMahon DG, Schunack W, Datta P, Heidelberger R, Marshak DW
(2011) Invest Ophthalmol Vis Sci 52: 3083-8
MeSH Terms: Animals, Axons, Calcium, Dopamine, Dose-Response Relationship, Drug, Histamine, Histamine Agonists, Histamine H1 Antagonists, Mice, Mice, Transgenic, Receptors, Histamine H1, Retina
Added March 18, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Naringin is a major and selective clinical inhibitor of organic anion-transporting polypeptide 1A2 (OATP1A2) in grapefruit juice.
Bailey DG, Dresser GK, Leake BF, Kim RB
(2007) Clin Pharmacol Ther 81: 495-502
MeSH Terms: Adult, Anticoagulants, Beverages, Citrus paradisi, Cross-Over Studies, Data Interpretation, Statistical, Double-Blind Method, Drug Interactions, Female, Flavanones, Furocoumarins, HeLa Cells, Hesperidin, Histamine H1 Antagonists, Humans, Male, Middle Aged, Organic Anion Transporters, Reproducibility of Results, Terfenadine
Added March 27, 2014
1 Communities
1 Members
2 Resources
20 MeSH Terms
Intestinal drug transporter expression and the impact of grapefruit juice in humans.
Glaeser H, Bailey DG, Dresser GK, Gregor JC, Schwarz UI, McGrath JS, Jolicoeur E, Lee W, Leake BF, Tirona RG, Kim RB
(2007) Clin Pharmacol Ther 81: 362-70
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Adult, Aged, Aged, 80 and over, Beverages, Biological Availability, Blotting, Western, Carrier Proteins, Citrus paradisi, Cytochrome P-450 CYP3A, Cytochrome P-450 Enzyme System, Female, Fluorescent Antibody Technique, Food-Drug Interactions, Histamine H1 Antagonists, Humans, Immunohistochemistry, Intestinal Mucosa, Male, Middle Aged, Organic Anion Transporters, Pharmaceutical Preparations, RNA, Reverse Transcriptase Polymerase Chain Reaction, Terfenadine
Added March 27, 2014
1 Communities
1 Members
2 Resources
25 MeSH Terms
Hyperadrenergic postural tachycardia syndrome in mast cell activation disorders.
Shibao C, Arzubiaga C, Roberts LJ, Raj S, Black B, Harris P, Biaggioni I
(2005) Hypertension 45: 385-90
MeSH Terms: Adrenergic beta-Antagonists, Adult, Autonomic Nervous System, Case-Control Studies, Female, Histamine H1 Antagonists, Histamine H2 Antagonists, Humans, Hypotension, Orthostatic, Mast Cells, Methyldopa, Sympatholytics, Syndrome, Tachycardia
Added December 10, 2013
0 Communities
3 Members
0 Resources
14 MeSH Terms
Are herbal products dietary supplements or drugs? An important question for public safety.
Stein CM
(2002) Clin Pharmacol Ther 71: 411-3
MeSH Terms: Anti-Allergic Agents, Cardiovascular System, Ephedra, Histamine H1 Antagonists, Humans, Hypericum, Pharmacokinetics, Plant Extracts, Terfenadine, United States, United States Food and Drug Administration
Added December 10, 2013
0 Communities
1 Members
0 Resources
11 MeSH Terms
Fruit juices inhibit organic anion transporting polypeptide-mediated drug uptake to decrease the oral availability of fexofenadine.
Dresser GK, Bailey DG, Leake BF, Schwarz UI, Dawson PA, Freeman DJ, Kim RB
(2002) Clin Pharmacol Ther 71: 11-20
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Administration, Oral, Adult, Area Under Curve, Beverages, Biological Availability, Carrier Proteins, Citrus, Double-Blind Method, Female, Flavonoids, Food-Drug Interactions, Fruit, HeLa Cells, Histamine H1 Antagonists, Humans, Intestinal Absorption, Male, Malus, Membrane Transport Proteins, Organic Anion Transporters, Organic Anion Transporters, Sodium-Dependent, Symporters, Terfenadine
Added March 27, 2014
1 Communities
1 Members
2 Resources
24 MeSH Terms
Voltage-dependent, pertussis toxin insensitive inhibition of calcium currents by histamine in bovine adrenal chromaffin cells.
Currie KP, Fox AP
(2000) J Neurophysiol 83: 1435-42
MeSH Terms: Adenosine Triphosphate, Animals, Autocrine Communication, Calcium Channel Blockers, Calcium Channels, N-Type, Calcium Channels, Q-Type, Catecholamines, Cattle, Chelating Agents, Chromaffin Cells, Dinoprostone, Egtazic Acid, Electrophysiology, GTP-Binding Proteins, Histamine, Histamine Agonists, Histamine H1 Antagonists, Membrane Potentials, Paracrine Communication, Patch-Clamp Techniques, Pertussis Toxin, Virulence Factors, Bordetella
Added March 30, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
Neurotensin depolarizes cholinergic and a subset of non-cholinergic septal/diagonal band neurons by stimulating neurotensin-1 receptors.
Matthews RT
(1999) Neuroscience 94: 775-83
MeSH Terms: Action Potentials, Adamantane, Animals, Dose-Response Relationship, Drug, Female, Guinea Pigs, Histamine H1 Antagonists, Imidazoles, In Vitro Techniques, Male, Membrane Potentials, Neurons, Neurotensin, Patch-Clamp Techniques, Piperidines, Prosencephalon, Receptors, Neurotensin, Tetrodotoxin
Added January 20, 2015
0 Communities
1 Members
0 Resources
18 MeSH Terms
OATP and P-glycoprotein transporters mediate the cellular uptake and excretion of fexofenadine.
Cvetkovic M, Leake B, Fromm MF, Wilkinson GR, Kim RB
(1999) Drug Metab Dispos 27: 866-71
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Animals, Anion Transport Proteins, Biological Transport, Active, Caco-2 Cells, Carrier Proteins, Genes, MDR, HeLa Cells, Histamine H1 Antagonists, Humans, LLC-PK1 Cells, Mice, Rats, Swine, Terfenadine, Tissue Distribution, Transfection, Vaccinia virus
Added March 27, 2014
0 Communities
1 Members
0 Resources
18 MeSH Terms
A phase II study of vinblastine in combination with acrivastine in patients with advanced renal cell carcinoma.
Berlin J, King AC, Tutsch K, Findlay JW, Kohler P, Collier M, Clendeninn NJ, Wilding G
(1994) Invest New Drugs 12: 137-41
MeSH Terms: Adult, Aged, Carcinoma, Renal Cell, Drug Resistance, Multiple, Female, Histamine H1 Antagonists, Humans, Kidney Neoplasms, Male, Middle Aged, Neoplasm Staging, Triprolidine, Vinblastine
Added March 20, 2014
0 Communities
1 Members
0 Resources
13 MeSH Terms