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Dapagliflozin Does Not Directly Affect Human α or β Cells.
Dai C, Walker JT, Shostak A, Bouchi Y, Poffenberger G, Hart NJ, Jacobson DA, Calcutt MW, Bottino R, Greiner DL, Shultz LD, McGuinness OP, Dean ED, Powers AC
(2020) Endocrinology 161:
MeSH Terms: Adolescent, Adult, Animals, Benzhydryl Compounds, Cells, Cultured, Female, Glucagon, Glucagon-Secreting Cells, Glucosides, Heterografts, Humans, Insulin, Insulin Secretion, Insulin-Secreting Cells, Islets of Langerhans, Male, Mice, Mice, Inbred NOD, Mice, Transgenic, Middle Aged, Signal Transduction, Species Specificity, Young Adult
Added June 14, 2021
0 Communities
1 Members
0 Resources
MeSH Terms
Molecular subtypes of small cell lung cancer: a synthesis of human and mouse model data.
Rudin CM, Poirier JT, Byers LA, Dive C, Dowlati A, George J, Heymach JV, Johnson JE, Lehman JM, MacPherson D, Massion PP, Minna JD, Oliver TG, Quaranta V, Sage J, Thomas RK, Vakoc CR, Gazdar AF
(2019) Nat Rev Cancer 19: 289-297
MeSH Terms: Animals, Gene Expression Regulation, Neoplastic, Heterografts, Humans, Lung Neoplasms, Mice, Small Cell Lung Carcinoma, Transcription Factors, Transcription, Genetic
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Is a Tumor Suppressor Gene in Colorectal Cancer.
Chen MS, Lo YH, Chen X, Williams CS, Donnelly JM, Criss ZK, Patel S, Butkus JM, Dubrulle J, Finegold MJ, Shroyer NF
(2019) Mol Cancer Res 17: 697-708
MeSH Terms: Animals, Cell Line, Tumor, Colorectal Neoplasms, DNA-Binding Proteins, Genes, Tumor Suppressor, HCT116 Cells, HEK293 Cells, Heterografts, Humans, Male, Mice, Mice, Inbred NOD, Transcription Factors
Added April 15, 2019
0 Communities
1 Members
0 Resources
13 MeSH Terms
Consider Changing the Horse for Your CAR-T?
Wilson MH
(2018) Mol Ther 26: 1873-1874
MeSH Terms: Animals, Antigens, CD19, Heterografts, Horses, Immunoglobulin G, Immunotherapy, Adoptive, T-Lymphocytes
Added December 13, 2018
0 Communities
1 Members
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7 MeSH Terms
Ultrasound Measurement of Vascular Density to Evaluate Response to Anti-Angiogenic Therapy in Renal Cell Carcinoma.
Rojas JD, Papadopoulou V, Czernuszewicz TJ, Rajamahendiran RM, Chytil A, Chiang YC, Chong DC, Bautch VL, Rathmell WK, Aylward S, Gessner RC, Dayton PA
(2019) IEEE Trans Biomed Eng 66: 873-880
MeSH Terms: Angiogenesis Inhibitors, Angiography, Animals, Carcinoma, Renal Cell, Drug Monitoring, Female, Heterografts, Kidney, Kidney Neoplasms, Mice, Mice, Inbred NOD, Mice, SCID, Microvessels, Ultrasonography
Added October 30, 2019
0 Communities
1 Members
0 Resources
14 MeSH Terms
Epithelial-Mesenchymal Transition Induces Podocalyxin to Promote Extravasation via Ezrin Signaling.
Fröse J, Chen MB, Hebron KE, Reinhardt F, Hajal C, Zijlstra A, Kamm RD, Weinberg RA
(2018) Cell Rep 24: 962-972
MeSH Terms: Animals, Breast Neoplasms, Cell Line, Tumor, Cytoskeletal Proteins, Epithelial-Mesenchymal Transition, Female, Heterografts, Humans, Lung Neoplasms, Male, Mice, Mice, Inbred NOD, Mice, SCID, Pancreatic Neoplasms, Sialoglycoproteins, Signal Transduction
Added April 10, 2019
0 Communities
1 Members
0 Resources
16 MeSH Terms
Gallium Maltolate Disrupts Tumor Iron Metabolism and Retards the Growth of Glioblastoma by Inhibiting Mitochondrial Function and Ribonucleotide Reductase.
Chitambar CR, Al-Gizawiy MM, Alhajala HS, Pechman KR, Wereley JP, Wujek R, Clark PA, Kuo JS, Antholine WE, Schmainda KM
(2018) Mol Cancer Ther 17: 1240-1250
MeSH Terms: Animals, Antineoplastic Agents, Brain, Cell Line, Tumor, Disease Models, Animal, Glioblastoma, Heterografts, Humans, Immunohistochemistry, Iron, Male, Mitochondria, Organometallic Compounds, Pyrones, Rats, Receptors, Transferrin, Ribonucleoside Diphosphate Reductase, Ribonucleotide Reductases
Added March 6, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Lactate Metabolism in Human Lung Tumors.
Faubert B, Li KY, Cai L, Hensley CT, Kim J, Zacharias LG, Yang C, Do QN, Doucette S, Burguete D, Li H, Huet G, Yuan Q, Wigal T, Butt Y, Ni M, Torrealba J, Oliver D, Lenkinski RE, Malloy CR, Wachsmann JW, Young JD, Kernstine K, DeBerardinis RJ
(2017) Cell 171: 358-371.e9
MeSH Terms: Animals, Blood Chemical Analysis, Carcinoma, Non-Small-Cell Lung, Cell Line, Tumor, Citric Acid Cycle, Disease Models, Animal, Female, Glyceric Acids, Heterografts, Humans, Lactic Acid, Lung Neoplasms, Male, Mice, Monocarboxylic Acid Transporters, Neoplasm Transplantation, Symporters
Added March 28, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Prevention of breast cancer skeletal metastases with parathyroid hormone.
Swami S, Johnson J, Bettinson LA, Kimura T, Zhu H, Albertelli MA, Johnson RW, Wu JY
(2017) JCI Insight 2:
MeSH Terms: Animals, Bone Neoplasms, Breast Neoplasms, Cell Line, Tumor, Cellular Microenvironment, Female, Gene Expression Profiling, Heterografts, Liver Neoplasms, Lung Neoplasms, Mice, Parathyroid Hormone, Splenic Neoplasms, Survival Analysis, X-Ray Microtomography
Added March 26, 2019
0 Communities
1 Members
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15 MeSH Terms
Two distinct mTORC2-dependent pathways converge on Rac1 to drive breast cancer metastasis.
Morrison Joly M, Williams MM, Hicks DJ, Jones B, Sanchez V, Young CD, Sarbassov DD, Muller WJ, Brantley-Sieders D, Cook RS
(2017) Breast Cancer Res 19: 74
MeSH Terms: Animals, Breast Neoplasms, Cell Line, Tumor, Cell Movement, Disease Models, Animal, Female, Gene Amplification, Heterografts, Humans, Mechanistic Target of Rapamycin Complex 2, Mice, Mice, Transgenic, Neoplasm Metastasis, Neoplasm Staging, Prognosis, Proto-Oncogene Proteins c-akt, Rapamycin-Insensitive Companion of mTOR Protein, Receptor, ErbB-2, Signal Transduction, rac1 GTP-Binding Protein, rho Guanine Nucleotide Dissociation Inhibitor beta
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms