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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 19

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Regulation of the Pancreatic Exocrine Differentiation Program and Morphogenesis by Onecut 1/Hnf6.
Kropp PA, Zhu X, Gannon M
(2019) Cell Mol Gastroenterol Hepatol 7: 841-856
MeSH Terms: Acinar Cells, Animals, Animals, Newborn, Base Sequence, Cell Differentiation, Cell Proliferation, Embryo, Mammalian, Epithelium, Gene Expression Regulation, Developmental, Hepatocyte Nuclear Factor 6, Mice, Morphogenesis, Pancreas, Exocrine
Added March 29, 2019
1 Communities
1 Members
0 Resources
13 MeSH Terms
Cooperative function of Pdx1 and Oc1 in multipotent pancreatic progenitors impacts postnatal islet maturation and adaptability.
Kropp PA, Dunn JC, Carboneau BA, Stoffers DA, Gannon M
(2018) Am J Physiol Endocrinol Metab 314: E308-E321
MeSH Terms: Adaptation, Physiological, Animals, Animals, Newborn, Cell Differentiation, Cells, Cultured, Diet, High-Fat, Gene Expression Regulation, Developmental, Glucose, Hepatocyte Nuclear Factor 6, Homeodomain Proteins, Insulin-Secreting Cells, Islets of Langerhans, Male, Mice, Mice, Transgenic, Multipotent Stem Cells, Organogenesis, Trans-Activators
Added April 15, 2019
0 Communities
1 Members
0 Resources
MeSH Terms
Threshold-Dependent Cooperativity of Pdx1 and Oc1 in Pancreatic Progenitors Establishes Competency for Endocrine Differentiation and β-Cell Function.
Henley KD, Stanescu DE, Kropp PA, Wright CVE, Won KJ, Stoffers DA, Gannon M
(2016) Cell Rep 15: 2637-2650
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Count, Cell Differentiation, Embryo, Mammalian, Gene Dosage, Gene Expression Regulation, Developmental, Gene Ontology, Gene Regulatory Networks, Glucose, Hepatocyte Nuclear Factor 6, Heterozygote, Homeodomain Proteins, Homeostasis, Insulin-Secreting Cells, Mice, Multigene Family, Nerve Tissue Proteins, Stem Cells, Trans-Activators, Weaning
Added July 5, 2016
1 Communities
2 Members
0 Resources
21 MeSH Terms
Loss of HNF6 expression correlates with human pancreatic cancer progression.
Pekala KR, Ma X, Kropp PA, Petersen CP, Hudgens CW, Chung CH, Shi C, Merchant NB, Maitra A, Means AL, Gannon MA
(2014) Lab Invest 94: 517-27
MeSH Terms: Animals, Carcinoma, Pancreatic Ductal, Cell Line, Tumor, Disease Progression, Hepatocyte Nuclear Factor 6, Homeostasis, Humans, Liver Neoplasms, Experimental, Mice, Mice, Inbred C57BL, Pancreatic Neoplasms
Added March 26, 2014
1 Communities
3 Members
0 Resources
11 MeSH Terms
Intrahepatic bile duct regeneration in mice does not require Hnf6 or Notch signaling through Rbpj.
Walter TJ, Vanderpool C, Cast AE, Huppert SS
(2014) Am J Pathol 184: 1479-88
MeSH Terms: Animals, Bile Ducts, Intrahepatic, Epithelial Cells, Hepatocyte Nuclear Factor 6, Hepatocytes, Imaging, Three-Dimensional, Immunoglobulin J Recombination Signal Sequence-Binding Protein, Immunohistochemistry, Keratin-19, Mice, Knockout, Plant Lectins, Portal Vein, Receptors, Notch, Regeneration, SOX9 Transcription Factor
Added May 27, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Onecut1 is essential for horizontal cell genesis and retinal integrity.
Wu F, Li R, Umino Y, Kaczynski TJ, Sapkota D, Li S, Xiang M, Fliesler SJ, Sherry DM, Gannon M, Solessio E, Mu X
(2013) J Neurosci 33: 13053-65, 13065a
MeSH Terms: Animals, Cell Count, Cell Differentiation, Cell Survival, Embryo, Mammalian, Eye Proteins, Gene Expression Regulation, Developmental, Green Fluorescent Proteins, Hepatocyte Nuclear Factor 6, Homeodomain Proteins, Mice, Mice, Inbred C57BL, Mice, Transgenic, Nerve Tissue Proteins, Neural Pathways, Neurogenesis, Neuroglia, Neurons, Protein Kinase C-alpha, Retina, Retinal Horizontal Cells, Synapses, Transcription Factors
Added November 25, 2014
1 Communities
0 Members
1 Resources
23 MeSH Terms
Role of the ductal transcription factors HNF6 and Sox9 in pancreatic acinar-to-ductal metaplasia.
Prévot PP, Simion A, Grimont A, Colletti M, Khalaileh A, Van den Steen G, Sempoux C, Xu X, Roelants V, Hald J, Bertrand L, Heimberg H, Konieczny SF, Dor Y, Lemaigre FP, Jacquemin P
(2012) Gut 61: 1723-32
MeSH Terms: Acinar Cells, Animals, Biomarkers, Tumor, Blotting, Western, Cell Transformation, Neoplastic, Cells, Cultured, Guinea Pigs, Hepatocyte Nuclear Factor 6, Humans, Metaplasia, Mice, Models, Animal, Pancreas, Real-Time Polymerase Chain Reaction, Reverse Transcriptase Polymerase Chain Reaction, SOX9 Transcription Factor
Added September 26, 2012
0 Communities
0 Members
1 Resources
16 MeSH Terms
Renshaw cell interneuron specialization is controlled by a temporally restricted transcription factor program.
Stam FJ, Hendricks TJ, Zhang J, Geiman EJ, Francius C, Labosky PA, Clotman F, Goulding M
(2012) Development 139: 179-90
MeSH Terms: Animals, Bromodeoxyuridine, Cell Differentiation, Crosses, Genetic, Electrophysiology, Gene Expression Regulation, Developmental, Green Fluorescent Proteins, Hepatocyte Nuclear Factor 6, Homeodomain Proteins, Immunohistochemistry, Interneurons, Mice, Spinal Cord, Time Factors, Transcription Factors
Added February 17, 2012
1 Communities
1 Members
0 Resources
15 MeSH Terms
Genetic interactions between hepatocyte nuclear factor-6 and Notch signaling regulate mouse intrahepatic bile duct development in vivo.
Vanderpool C, Sparks EE, Huppert KA, Gannon M, Means AL, Huppert SS
(2012) Hepatology 55: 233-43
MeSH Terms: Animals, Bile Ducts, Intrahepatic, Cell Lineage, Cholestasis, Gene Expression Regulation, Developmental, Hepatocyte Nuclear Factor 1-beta, Hepatocyte Nuclear Factor 6, Hepatocytes, Immunoglobulin J Recombination Signal Sequence-Binding Protein, Immunoglobulin kappa-Chains, Integrases, Mice, Mice, Inbred Strains, Mice, Knockout, Receptors, Notch, SOX9 Transcription Factor, Signal Transduction
Added December 5, 2013
3 Communities
2 Members
1 Resources
17 MeSH Terms
A new set of classifications for ductal plate malformations.
Huppert SS
(2011) Hepatology 53: 1795-7
MeSH Terms: Animals, Bile Ducts, Intrahepatic, Biomarkers, Congenital Abnormalities, Disease Models, Animal, Hepatocyte Nuclear Factor 1-beta, Hepatocyte Nuclear Factor 4, Hepatocyte Nuclear Factor 6, Humans, Liver Diseases, Membrane Proteins, Mice, Mice, Knockout, Protein-Serine-Threonine Kinases, Receptor, Transforming Growth Factor-beta Type II, Receptors, Transforming Growth Factor beta, SOX9 Transcription Factor
Added July 16, 2011
1 Communities
1 Members
0 Resources
17 MeSH Terms