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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 15

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Cell-free hemoglobin augments acute kidney injury during experimental sepsis.
Shaver CM, Paul MG, Putz ND, Landstreet SR, Kuck JL, Scarfe L, Skrypnyk N, Yang H, Harrison FE, de Caestecker MP, Bastarache JA, Ware LB
(2019) Am J Physiol Renal Physiol 317: F922-F929
MeSH Terms: Acute Kidney Injury, Animals, Cell Line, Cell Survival, Cell-Free System, Cytokines, Female, Glomerular Filtration Rate, Hemoglobins, Hepatitis A Virus Cellular Receptor 1, Kidney Tubules, Lipocalin-2, Male, Mice, Mice, Inbred C57BL, Sepsis, Survival Analysis
Added May 10, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
CRISPR/Cas9 engineering of a KIM-1 reporter human proximal tubule cell line.
Veach RA, Wilson MH
(2018) PLoS One 13: e0204487
MeSH Terms: Acute Kidney Injury, CRISPR-Cas Systems, Cell Line, Cisplatin, Gene Knock-In Techniques, Gene Targeting, Genes, Reporter, Genetic Engineering, Glucose, Green Fluorescent Proteins, Hepatitis A Virus Cellular Receptor 1, Homologous Recombination, Humans, Kidney Tubules, Proximal, Luciferases, Up-Regulation
Added December 13, 2018
0 Communities
1 Members
0 Resources
16 MeSH Terms
Detection of Drug-Induced Acute Kidney Injury in Humans Using Urinary KIM-1, miR-21, -200c, and -423.
Pavkovic M, Robinson-Cohen C, Chua AS, Nicoara O, Cárdenas-González M, Bijol V, Ramachandran K, Hampson L, Pirmohamed M, Antoine DJ, Frendl G, Himmelfarb J, Waikar SS, Vaidya VS
(2016) Toxicol Sci 152: 205-13
MeSH Terms: Acetaminophen, Acute Kidney Injury, Adult, Biomarkers, Case-Control Studies, Cells, Cultured, Cisplatin, Cross-Sectional Studies, Dose-Response Relationship, Drug, Drug Overdose, Epithelial Cells, Female, Hepatitis A Virus Cellular Receptor 1, Humans, Kidney Tubules, Proximal, Longitudinal Studies, Male, MicroRNAs, Middle Aged, Predictive Value of Tests, Time Factors, Urinalysis, Young Adult
Added September 19, 2017
0 Communities
1 Members
0 Resources
23 MeSH Terms
KIM-1/TIM-1 in proximal tubular cell immune response.
Brooks CR, Bonventre JV
(2015) Oncotarget 6: 44059-60
MeSH Terms: Acute Kidney Injury, Animals, Apoptosis, Disease Models, Animal, Genotype, Hepatitis A Virus Cellular Receptor 1, Humans, Ischemia, Kidney Tubules, Proximal, Membrane Proteins, Mice, Transgenic, Phagocytosis, Phenotype, Signal Transduction
Added September 12, 2016
1 Communities
1 Members
0 Resources
14 MeSH Terms
KIM-1-/TIM-1-mediated phagocytosis links ATG5-/ULK1-dependent clearance of apoptotic cells to antigen presentation.
Brooks CR, Yeung MY, Brooks YS, Chen H, Ichimura T, Henderson JM, Bonventre JV
(2015) EMBO J 34: 2441-64
MeSH Terms: Antigen Presentation, Apoptosis, Autophagy-Related Protein 5, Autophagy-Related Protein-1 Homolog, CD4-Positive T-Lymphocytes, Cell Proliferation, HEK293 Cells, Hepatitis A Virus Cellular Receptor 1, Humans, Intracellular Signaling Peptides and Proteins, Lipoylation, Membrane Glycoproteins, Microtubule-Associated Proteins, Phagocytosis, Protein Serine-Threonine Kinases, Reactive Oxygen Species, Receptors, Virus
Added September 12, 2016
1 Communities
1 Members
0 Resources
17 MeSH Terms
KIM-1-mediated phagocytosis reduces acute injury to the kidney.
Yang L, Brooks CR, Xiao S, Sabbisetti V, Yeung MY, Hsiao LL, Ichimura T, Kuchroo V, Bonventre JV
(2015) J Clin Invest 125: 1620-36
MeSH Terms: Acute Kidney Injury, Animals, Apoptosis, Cisplatin, Cytokines, Epithelial Cells, Extracellular Matrix Proteins, Gene Expression Regulation, Hepatitis A Virus Cellular Receptor 1, Homeodomain Proteins, Immunity, Innate, Inflammation, Intercellular Signaling Peptides and Proteins, Kidney, Kidney Tubules, Proximal, LLC-PK1 Cells, Macrophage Activation, Male, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Knockout, NF-kappa B, Phagocytosis, Phosphatidylinositol 3-Kinases, Protein Structure, Tertiary, Radiation Chimera, Reperfusion Injury, Swine
Added September 12, 2016
1 Communities
1 Members
0 Resources
29 MeSH Terms
Furosemide Stress Test and Biomarkers for the Prediction of AKI Severity.
Koyner JL, Davison DL, Brasha-Mitchell E, Chalikonda DM, Arthur JM, Shaw AD, Tumlin JA, Trevino SA, Bennett MR, Kimmel PL, Seneff MG, Chawla LS
(2015) J Am Soc Nephrol 26: 2023-31
MeSH Terms: Acute Kidney Injury, Acute-Phase Proteins, Aged, Albuminuria, Biomarkers, Creatinine, Disease Progression, Diuretics, Female, Furosemide, Hepatitis A Virus Cellular Receptor 1, Humans, Insulin-Like Growth Factor Binding Proteins, Interleukin-18, Lipocalin-2, Lipocalins, Male, Membrane Glycoproteins, Middle Aged, Proto-Oncogene Proteins, Receptors, Virus, Severity of Illness Index, Sodium, Tissue Inhibitor of Metalloproteinase-2, Uromodulin
Added October 20, 2015
0 Communities
1 Members
0 Resources
25 MeSH Terms
TIM-1 signaling is required for maintenance and induction of regulatory B cells.
Yeung MY, Ding Q, Brooks CR, Xiao S, Workman CJ, Vignali DA, Ueno T, Padera RF, Kuchroo VK, Najafian N, Rothstein DM
(2015) Am J Transplant 15: 942-53
MeSH Terms: Animals, B-Lymphocytes, Regulatory, Graft Survival, Hepatitis A Virus Cellular Receptor 1, Interleukin-10, Membrane Proteins, Mice, Mice, Inbred BALB C, Signal Transduction
Added September 12, 2016
1 Communities
1 Members
0 Resources
9 MeSH Terms
Tim-1 is essential for induction and maintenance of IL-10 in regulatory B cells and their regulation of tissue inflammation.
Xiao S, Brooks CR, Sobel RA, Kuchroo VK
(2015) J Immunol 194: 1602-8
MeSH Terms: Animals, B-Lymphocytes, Regulatory, Encephalomyelitis, Autoimmune, Experimental, Flow Cytometry, Hepatitis A Virus Cellular Receptor 1, Inflammation, Interleukin-10, Lymphocyte Activation, Membrane Proteins, Mice, Mice, Inbred C57BL, Mice, Mutant Strains, Real-Time Polymerase Chain Reaction, Self Tolerance
Added September 12, 2016
1 Communities
1 Members
0 Resources
14 MeSH Terms
Urinary L-FABP predicts poor outcomes in critically ill patients with early acute kidney injury.
Parr SK, Clark AJ, Bian A, Shintani AK, Wickersham NE, Ware LB, Ikizler TA, Siew ED
(2015) Kidney Int 87: 640-8
MeSH Terms: APACHE, Acute Kidney Injury, Acute-Phase Proteins, Aged, Area Under Curve, Biomarkers, Creatinine, Critical Illness, Disease Progression, Early Diagnosis, Fatty Acid-Binding Proteins, Female, Hepatitis A Virus Cellular Receptor 1, Humans, Interleukin-18, Lipocalin-2, Lipocalins, Male, Membrane Glycoproteins, Middle Aged, Predictive Value of Tests, Proto-Oncogene Proteins, ROC Curve, Receptors, Virus, Renal Dialysis
Added September 29, 2014
0 Communities
3 Members
0 Resources
25 MeSH Terms