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Results: 1 to 6 of 6

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Excess of heme induces tissue factor-dependent activation of coagulation in mice.
Sparkenbaugh EM, Chantrathammachart P, Wang S, Jonas W, Kirchhofer D, Gailani D, Gruber A, Kasthuri R, Key NS, Mackman N, Pawlinski R
(2015) Haematologica 100: 308-14
MeSH Terms: Anemia, Hemolytic, Anemia, Sickle Cell, Animals, Antibodies, Blood Coagulation, Capillary Permeability, Cells, Cultured, Factor XI, Factor XIIa, Female, Gene Deletion, Gene Expression, Heme, Hemopexin, Humans, Injections, Intravenous, Leukocytes, Mononuclear, Macrophages, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, RNA, Small Interfering, Swine, Thromboplastin
Added January 20, 2015
0 Communities
1 Members
0 Resources
25 MeSH Terms
Association between haptoglobin, hemopexin and mortality in adults with sepsis.
Janz DR, Bastarache JA, Sills G, Wickersham N, May AK, Bernard GR, Ware LB
(2013) Crit Care 17: R272
MeSH Terms: Aged, Biomarkers, Female, Haptoglobins, Hemopexin, Hospital Mortality, Humans, Intensive Care Units, Logistic Models, Male, Middle Aged, Prognosis, Sepsis, Survival Analysis
Added March 7, 2014
0 Communities
2 Members
0 Resources
14 MeSH Terms
Distinct functions for the catalytic and hemopexin domains of a Drosophila matrix metalloproteinase.
Glasheen BM, Kabra AT, Page-McCaw A
(2009) Proc Natl Acad Sci U S A 106: 2659-64
MeSH Terms: Animals, Blotting, Western, Catalytic Domain, Drosophila melanogaster, Hemopexin, Matrix Metalloproteinases
Added March 5, 2014
0 Communities
1 Members
0 Resources
6 MeSH Terms
Role for copper in transient oxidation and nuclear translocation of MTF-1, but not of NF-kappa B, by the heme-hemopexin transport system.
Vanacore RM, Eskew JD, Morales PJ, Sung L, Smith A
(2000) Antioxid Redox Signal 2: 739-52
MeSH Terms: Animals, Base Sequence, Binding Sites, Biological Transport, Active, Cell Nucleus, Cells, Cultured, Chelating Agents, Copper, DNA Primers, DNA-Binding Proteins, Heme, Heme Oxygenase (Decyclizing), Heme Oxygenase-1, Hemopexin, Humans, Membrane Proteins, Metallothionein, Mice, NF-kappa B, Oxidation-Reduction, Phenanthrolines, Transcription Factors, Upstream Stimulatory Factors
Added August 21, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms
Cellular protection mechanisms against extracellular heme. heme-hemopexin, but not free heme, activates the N-terminal c-jun kinase.
Eskew JD, Vanacore RM, Sung L, Morales PJ, Smith A
(1999) J Biol Chem 274: 638-48
MeSH Terms: Animals, Apoptosis, Base Sequence, Biological Transport, Calcium-Calmodulin-Dependent Protein Kinases, Cell Division, Cell Nucleus, Cyclin-Dependent Kinase Inhibitor p21, Cyclins, DNA Primers, Enzyme Activation, Heme, Hemopexin, JNK Mitogen-Activated Protein Kinases, Mice, Mitogen-Activated Protein Kinases, NF-kappa B, Protein Serine-Threonine Kinases, Proto-Oncogene Proteins, Proto-Oncogene Proteins c-akt, Proto-Oncogene Proteins c-jun, Tumor Cells, Cultured
Added August 21, 2013
0 Communities
1 Members
0 Resources
22 MeSH Terms
Role of heme-hemopexin in human T-lymphocyte proliferation.
Smith A, Eskew JD, Borza CM, Pendrak M, Hunt RC
(1997) Exp Cell Res 232: 246-54
MeSH Terms: Animals, Cell Division, Deferoxamine, Heme, Hemopexin, Humans, Iron, Leukemia-Lymphoma, Adult T-Cell, Mice, Neoplasm Proteins, Protein Kinase C, Protoporphyrins, Receptors, Peptide, T-Lymphocytes, Tumor Cells, Cultured
Added August 22, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms