Electrophysiologic and molecular mechanisms of a frameshift NPPA mutation linked with familial atrial fibrillation.
Menon A, Hong L, Savio-Galimberti E, Sridhar A, Youn SW, Zhang M, Kor K, Blair M, Kupershmidt S, Darbar D
(2019) J Mol Cell Cardiol 132
: 24-35MeSH Terms: Action Potentials, Animals, Atrial Fibrillation, Atrial Natriuretic Factor, Electrophysiological Phenomena, Frameshift Mutation, Heart Atria, Humans, Membrane Potentials, Mice, Mice, Transgenic, Myocytes, Cardiac, NAV1.5 Voltage-Gated Sodium ChannelAdded June 14, 2019
13 MeSH Terms
Transcription factor ETV1 is essential for rapid conduction in the heart.
Shekhar A, Lin X, Liu FY, Zhang J, Mo H, Bastarache L, Denny JC, Cox NJ, Delmar M, Roden DM, Fishman GI, Park DS
(2016) J Clin Invest 126
: 4444-4459MeSH Terms: Animals, DNA-Binding Proteins, Heart Atria, Heart Conduction System, Heart Ventricles, Homeobox Protein Nkx-2.5, Humans, Mice, Mice, Transgenic, Myocardium, Myocytes, Cardiac, NAV1.5 Voltage-Gated Sodium Channel, Transcription FactorsAdded March 14, 2018
13 MeSH Terms
Hypertension is associated with preamyloid oligomers in human atrium: a missing link in atrial pathophysiology?
Sidorova TN, Mace LC, Wells KS, Yermalitskaya LV, Su PF, Shyr Y, Atkinson JB, Fogo AB, Prinsen JK, Byrne JG, Petracek MR, Greelish JP, Hoff SJ, Ball SK, Glabe CG, Brown NJ, Barnett JV, Murray KT
(2014) J Am Heart Assoc 3
: e001384MeSH Terms: Aged, Amyloid beta-Protein Precursor, Atrial Function, Atrial Natriuretic Factor, Female, Fibrosis, Heart Atria, Humans, Hypertension, Immunohistochemistry, Male, Middle Aged, Prealbumin, Protein Aggregates, Randomized Controlled Trials as TopicAdded January 20, 2015
15 MeSH Terms
Reactive γ-ketoaldehydes promote protein misfolding and preamyloid oligomer formation in rapidly-activated atrial cells.
Sidorova TN, Yermalitskaya LV, Mace LC, Wells KS, Boutaud O, Prinsen JK, Davies SS, Roberts LJ, Dikalov SI, Glabe CG, Amarnath V, Barnett JV, Murray KT
(2015) J Mol Cell Cardiol 79
: 295-302MeSH Terms: Aldehydes, Amines, Amyloid, Animals, Atrial Natriuretic Factor, Cardiac Pacing, Artificial, Cell Line, Curcumin, Cytosol, Heart Atria, Humans, Mice, Models, Biological, Oxidative Stress, Protein Folding, Protein Multimerization, SuperoxidesAdded December 5, 2014
17 MeSH Terms
Alternating membrane potential/calcium interplay underlies repetitive focal activity in a genetic model of calcium-dependent atrial arrhythmias.
Lou Q, Belevych AE, Radwański PB, Liu B, Kalyanasundaram A, Knollmann BC, Fedorov VV, Györke S
(2015) J Physiol 593
: 1443-58MeSH Terms: Action Potentials, Animals, Atrial Fibrillation, Calcium Signaling, Calsequestrin, Cells, Cultured, Heart Atria, Membrane Potentials, Mice, Myocytes, Cardiac, PeriodicityAdded February 12, 2015
11 MeSH Terms
6 MeSH Terms
Atrial dissociation in a middle aged patient: a case report.
Hajsadeghi S, Oraii S, Riahi H, Sezavar SH, Ghanooni AH, Jafarian Kerman SR, Ahmahi R
(2014) Acta Med Iran 52
: 641-3MeSH Terms: Angina, Unstable, Chest Pain, Diagnosis, Differential, Electrocardiography, Emergency Service, Hospital, Heart Atria, Humans, Male, Middle AgedAdded April 25, 2016
9 MeSH Terms
Quantitative Imaging of Preamyloid Oligomers, a Novel Structural Abnormality, in Human Atrial Samples.
Sidorova TN, Mace LC, Wells KS, Yermalitskaya LV, Su PF, Shyr Y, Byrne JG, Petracek MR, Greelish JP, Hoff SJ, Ball SK, Glabe CG, Brown NJ, Barnett JV, Murray KT
(2014) J Histochem Cytochem 62
: 479-87MeSH Terms: Amyloid, Heart, Heart Atria, Humans, Immunohistochemistry, Microscopy, Confocal, MyocardiumAdded May 27, 2014
7 MeSH Terms
2014 AHA/ACC/HRS guideline for the management of patients with atrial fibrillation: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines and the Heart Rhythm Society.
January CT, Wann LS, Alpert JS, Calkins H, Cigarroa JE, Cleveland JC, Conti JB, Ellinor PT, Ezekowitz MD, Field ME, Murray KT, Sacco RL, Stevenson WG, Tchou PJ, Tracy CM, Yancy CW, American College of Cardiology/American Heart Association Task Force on Practice Guidelines
(2014) J Am Coll Cardiol 64
: e1-76MeSH Terms: Anti-Arrhythmia Agents, Anticoagulants, Arrhythmias, Cardiac, Atrial Fibrillation, Autonomic Nervous System, C-Reactive Protein, Cardiac Output, Low, Catheter Ablation, Comorbidity, Defibrillators, Implantable, Echocardiography, Transesophageal, Electric Countershock, Electrocardiography, Fibrinolytic Agents, Heart Atria, Heart Conduction System, Humans, Inflammation, Natriuretic Peptide, Brain, Oxidative Stress, Pacemaker, Artificial, Platelet Aggregation Inhibitors, Renin-Angiotensin System, Risk Assessment, Risk Factors, Septal Occluder Device, Stroke, Thromboembolism, Ventricular RemodelingAdded May 27, 2014
29 MeSH Terms
Gremlin 2 promotes differentiation of embryonic stem cells to atrial fate by activation of the JNK signaling pathway.
Tanwar V, Bylund JB, Hu J, Yan J, Walthall JM, Mukherjee A, Heaton WH, Wang WD, Potet F, Rai M, Kupershmidt S, Knapik EW, Hatzopoulos AK
(2014) Stem Cells 32
: 1774-88MeSH Terms: Animals, Cell Differentiation, Cells, Cultured, Cytokines, Embryonic Stem Cells, Heart Atria, MAP Kinase Signaling System, Mice, Myocytes, Cardiac, ProteinsAdded May 27, 2014
10 MeSH Terms