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A vast resource of allelic expression data spanning human tissues.
Castel SE, Aguet F, Mohammadi P, GTEx Consortium, Ardlie KG, Lappalainen T
(2020) Genome Biol 21: 234
MeSH Terms: Alleles, Gene Expression, Genome, Human, Haplotypes, Humans, Polymorphism, Single Nucleotide, Sequence Analysis, RNA
Added September 15, 2020
0 Communities
1 Members
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7 MeSH Terms
Inferred divergent gene regulation in archaic hominins reveals potential phenotypic differences.
Colbran LL, Gamazon ER, Zhou D, Evans P, Cox NJ, Capra JA
(2019) Nat Ecol Evol 3: 1598-1606
MeSH Terms: Animals, Female, Genome, Human, Haplotypes, Hominidae, Humans, Neanderthals, Phenotype
Added October 12, 2019
0 Communities
2 Members
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8 MeSH Terms
The Impact of Natural Selection on the Evolution and Function of Placentally Expressed Galectins.
Ely ZA, Moon JM, Sliwoski GR, Sangha AK, Shen XX, Labella AL, Meiler J, Capra JA, Rokas A
(2019) Genome Biol Evol 11: 2574-2592
MeSH Terms: Animals, Biological Evolution, Eutheria, Evolution, Molecular, Female, Galectins, Haplotypes, Humans, Models, Molecular, Phylogeny, Placenta, Polymorphism, Single Nucleotide, Pregnancy, Selection, Genetic
Added March 3, 2020
0 Communities
2 Members
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14 MeSH Terms
Immune Regulation in Eutherian Pregnancy: Live Birth Coevolved with Novel Immune Genes and Gene Regulation.
Moon JM, Capra JA, Abbot P, Rokas A
(2019) Bioessays 41: e1900072
MeSH Terms: Animals, Biological Evolution, Eutheria, Female, Gene Duplication, Gene Expression Regulation, Genetic Variation, Haplotypes, Humans, Live Birth, Pregnancy, Pregnancy, Animal, Regulatory Sequences, Nucleic Acid, Retroviridae, Selection, Genetic
Added March 3, 2020
0 Communities
1 Members
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15 MeSH Terms
Mitochondrial DNA Haplogroups and Delirium During Sepsis.
Samuels DC, Hulgan T, Fessel JP, Billings FT, Thompson JL, Chandrasekhar R, Girard TD
(2019) Crit Care Med 47: 1065-1071
MeSH Terms: Adult, African Americans, Critical Illness, DNA, Mitochondrial, Female, Haplotypes, Humans, Male, Middle Aged, Polymerase Chain Reaction, Retrospective Studies, Sepsis-Associated Encephalopathy, Sequence Analysis, DNA, Whites
Added December 11, 2019
0 Communities
1 Members
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14 MeSH Terms
Novel HLA Class I Alleles Outside the Extended DR3 Haplotype Are Protective against Autoimmune Hepatitis.
Lammert C, McKinnon EJ, Chalasani N, Phillips EJ
(2019) Clin Transl Gastroenterol 10: e00032
MeSH Terms: Adult, Aged, Alleles, Female, Genetic Predisposition to Disease, HLA-DQ beta-Chains, HLA-DRB1 Chains, Haplotypes, Hepatitis, Autoimmune, Heterozygote, Humans, Male, Middle Aged, Young Adult
Added March 30, 2020
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1 Members
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14 MeSH Terms
The role of HLA-A*33:01 in patients with cholestatic hepatitis attributed to terbinafine.
Fontana RJ, Cirulli ET, Gu J, Kleiner D, Ostrov D, Phillips E, Schutte R, Barnhart H, Chalasani N, Watkins PB, Hoofnagle JH
(2018) J Hepatol 69: 1317-1325
MeSH Terms: Adult, Aged, Alanine Transaminase, Alkaline Phosphatase, Antifungal Agents, Biomarkers, Chemical and Drug Induced Liver Injury, Cholestasis, Female, Follow-Up Studies, HLA-A Antigens, HLA-B14 Antigen, Haplotypes, Humans, Liver, Male, Middle Aged, Molecular Docking Simulation, Polymorphism, Genetic, Prospective Studies, Protein Binding, Terbinafine
Added March 30, 2020
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1 Members
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MeSH Terms
Nuclear-Mitochondrial interactions influence susceptibility to HIV-associated neurocognitive impairment.
Smieszek S, Jia P, Samuels DC, Zhao Z, Barnholtz-Sloan J, Kaur H, Letendre S, Ellis R, Franklin DR, Hulgan T, Kallianpur A, Bush WS, CHARTER Study Group
(2019) Mitochondrion 46: 247-255
MeSH Terms: AIDS Dementia Complex, Cell Nucleus, Genetic Association Studies, HIV Infections, Haplotypes, Humans, Mitochondria, Mitochondrial Proteins, Nuclear Proteins, Polymorphism, Single Nucleotide, Prospective Studies, Racial Groups
Added December 11, 2019
0 Communities
1 Members
0 Resources
12 MeSH Terms
The Role of Mitochondrial DNA Variation in Age-Related Decline in Gait Speed Among Older Men Living With Human Immunodeficiency Virus.
Sun J, Brown TT, Samuels DC, Hulgan T, D'Souza G, Jamieson BD, Erlandson KM, Martinson J, Palella FJ, Margolick JB, Kirk GD, Schrack JA
(2018) Clin Infect Dis 67: 778-784
MeSH Terms: Age Factors, Aging, Body Composition, Cohort Studies, DNA, Mitochondrial, Genetic Variation, HIV Infections, Haplotypes, Humans, Logistic Models, Male, Middle Aged, Odds Ratio, Risk Factors, Sexual and Gender Minorities, Walking Speed
Added March 21, 2018
0 Communities
2 Members
0 Resources
16 MeSH Terms
Mitochondrial Haplogroups Modify the Effect of Diabetes Duration and HbA1c on Proliferative Diabetic Retinopathy Risk in Patients With Type 2 Diabetes.
Mitchell SL, Neininger AC, Bruce CN, Chocron IM, Bregman JA, Estopinal CB, Muhammad A, Umfress AC, Jarrell KL, Warden C, Harlow PA, Wellons M, Samuels DC, Brantley MA
(2017) Invest Ophthalmol Vis Sci 58: 6481-6488
MeSH Terms: Aged, Blood Glucose, Case-Control Studies, DNA, Mitochondrial, Diabetes Mellitus, Type 2, Diabetic Retinopathy, Female, Glycated Hemoglobin A, Haplotypes, Humans, Male, Mitochondria, Polymorphism, Single Nucleotide, Risk Factors, United States, Whites
Added March 21, 2018
0 Communities
1 Members
0 Resources
16 MeSH Terms