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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 54

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Haloperidol and Ziprasidone for Treatment of Delirium in Critical Illness.
Girard TD, Exline MC, Carson SS, Hough CL, Rock P, Gong MN, Douglas IS, Malhotra A, Owens RL, Feinstein DJ, Khan B, Pisani MA, Hyzy RC, Schmidt GA, Schweickert WD, Hite RD, Bowton DL, Masica AL, Thompson JL, Chandrasekhar R, Pun BT, Strength C, Boehm LM, Jackson JC, Pandharipande PP, Brummel NE, Hughes CG, Patel MB, Stollings JL, Bernard GR, Dittus RS, Ely EW, MIND-USA Investigators
(2018) N Engl J Med 379: 2506-2516
MeSH Terms: Aged, Antipsychotic Agents, Critical Illness, Delirium, Dopamine Antagonists, Double-Blind Method, Female, Haloperidol, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Piperazines, Respiratory Insufficiency, Shock, Thiazoles, Treatment Failure
Added October 23, 2018
0 Communities
2 Members
0 Resources
17 MeSH Terms
Discovery, Structure-Activity Relationship, and Biological Characterization of a Novel Series of 6-((1 H-Pyrazolo[4,3- b]pyridin-3-yl)amino)-benzo[ d]isothiazole-3-carboxamides as Positive Allosteric Modulators of the Metabotropic Glutamate Receptor 4 (mGlu).
Bollinger SR, Engers DW, Panarese JD, West M, Engers JL, Loch MT, Rodriguez AL, Blobaum AL, Jones CK, Thompson Gray A, Conn PJ, Lindsley CW, Niswender CM, Hopkins CR
(2019) J Med Chem 62: 342-358
MeSH Terms: Allosteric Regulation, Amides, Animals, Brain, Catalepsy, Cytochrome P-450 CYP1A2, Half-Life, Haloperidol, Humans, Isoxazoles, Male, Rats, Rats, Sprague-Dawley, Receptors, Metabotropic Glutamate, Structure-Activity Relationship
Added March 3, 2020
0 Communities
2 Members
0 Resources
MeSH Terms
Effect of psychotropic drug treatment on sterol metabolism.
Korade Ž, Liu W, Warren EB, Armstrong K, Porter NA, Konradi C
(2017) Schizophr Res 187: 74-81
MeSH Terms: Adult, Animals, Antidepressive Agents, Antipsychotic Agents, Body Mass Index, Cholestadienols, Clozapine, Dehydrocholesterols, Female, Haloperidol, Humans, Lipid Metabolism, Male, Mental Disorders, Psychiatric Status Rating Scales, Random Allocation, Rats, Sprague-Dawley, Weight Gain
Added April 6, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
Dopaminergic contributions to working memory-related brain activation in postmenopausal women.
Dumas JA, Filippi CG, Newhouse PA, Naylor MR
(2017) Menopause 24: 163-170
MeSH Terms: Brain, Bromocriptine, Cognition, Dopamine Antagonists, Female, Haloperidol, Healthy Volunteers, Humans, Magnetic Resonance Imaging, Memory, Short-Term, Middle Aged, Postmenopause
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Development and Antiparkinsonian Activity of VU0418506, a Selective Positive Allosteric Modulator of Metabotropic Glutamate Receptor 4 Homomers without Activity at mGlu2/4 Heteromers.
Niswender CM, Jones CK, Lin X, Bubser M, Thompson Gray A, Blobaum AL, Engers DW, Rodriguez AL, Loch MT, Daniels JS, Lindsley CW, Hopkins CR, Javitch JA, Conn PJ
(2016) ACS Chem Neurosci 7: 1201-11
MeSH Terms: Allosteric Regulation, Animals, Antiparkinson Agents, Antipsychotic Agents, Apomorphine, Brain, Catalepsy, Disease Models, Animal, Dopamine Agonists, Forelimb, Glutamic Acid, HEK293 Cells, Haloperidol, Humans, Oxidopamine, Parkinson Disease, Rats, Rats, Sprague-Dawley, Receptors, Metabotropic Glutamate, Transfection
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
mTORC2/rictor signaling disrupts dopamine-dependent behaviors via defects in striatal dopamine neurotransmission.
Dadalko OI, Siuta M, Poe A, Erreger K, Matthies HJ, Niswender K, Galli A
(2015) J Neurosci 35: 8843-54
MeSH Terms: Amphetamine, Animals, Carrier Proteins, Dopamine, Dopamine Agents, Dopamine Plasma Membrane Transport Proteins, Dose-Response Relationship, Drug, Gene Expression Regulation, Haloperidol, In Vitro Techniques, Male, Mice, Mice, Inbred C57BL, Mice, Transgenic, Motor Activity, Nestin, Oncogene Protein v-akt, Rapamycin-Insensitive Companion of mTOR Protein, Serine, Signal Transduction, Synaptic Transmission, Tyrosine 3-Monooxygenase
Added February 15, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms
Pharmacological stimulation of metabotropic glutamate receptor type 4 in a rat model of Parkinson's disease and L-DOPA-induced dyskinesia: Comparison between a positive allosteric modulator and an orthosteric agonist.
Iderberg H, Maslava N, Thompson AD, Bubser M, Niswender CM, Hopkins CR, Lindsley CW, Conn PJ, Jones CK, Cenci MA
(2015) Neuropharmacology 95: 121-9
MeSH Terms: Aminobutyrates, Animals, Antiparkinson Agents, Catalepsy, Dyskinesia, Drug-Induced, Excitatory Amino Acid Agents, Haloperidol, Levodopa, Male, Oxidopamine, Parkinsonian Disorders, Phosphinic Acids, Picolinic Acids, Random Allocation, Rats, Sprague-Dawley, Receptors, Metabotropic Glutamate
Added February 18, 2016
0 Communities
3 Members
0 Resources
16 MeSH Terms
Discovery of (S)-2-cyclopentyl-N-((1-isopropylpyrrolidin2-yl)-9-methyl-1-oxo-2,9-dihydro-1H-pyrrido[3,4-b]indole-4-carboxamide (VU0453379): a novel, CNS penetrant glucagon-like peptide 1 receptor (GLP-1R) positive allosteric modulator (PAM).
Morris LC, Nance KD, Gentry PR, Days EL, Weaver CD, Niswender CM, Thompson AD, Jones CK, Locuson CW, Morrison RD, Daniels JS, Niswender KD, Lindsley CW
(2014) J Med Chem 57: 10192-7
MeSH Terms: Allosteric Regulation, Animals, Catalepsy, Central Nervous System Agents, Drug Synergism, Exenatide, Glucagon-Like Peptide 1, Glucagon-Like Peptide-1 Receptor, Haloperidol, High-Throughput Screening Assays, Indoles, Insulin, Insulin Secretion, Islets of Langerhans, Male, Mice, Inbred C57BL, Microsomes, Liver, Peptides, Pyrrolidines, Receptors, Glucagon, Structure-Activity Relationship, Venoms
Added February 16, 2015
0 Communities
4 Members
0 Resources
22 MeSH Terms
Conserved chromosome 2q31 conformations are associated with transcriptional regulation of GAD1 GABA synthesis enzyme and altered in prefrontal cortex of subjects with schizophrenia.
Bharadwaj R, Jiang Y, Mao W, Jakovcevski M, Dincer A, Krueger W, Garbett K, Whittle C, Tushir JS, Liu J, Sequeira A, Vawter MP, Gardner PD, Casaccia P, Rasmussen T, Bunney WE, Mirnics K, Futai K, Akbarian S
(2013) J Neurosci 33: 11839-51
MeSH Terms: Animals, Antipsychotic Agents, Cells, Cultured, Chromosomes, Human, Pair 2, Clozapine, DNA Methylation, Down-Regulation, Fibroblasts, Gene Expression Regulation, Glutamate Decarboxylase, Haloperidol, Hippocampus, Histones, Humans, Mice, Mice, Transgenic, Neurons, Prefrontal Cortex, Schizophrenia
Added May 19, 2014
0 Communities
1 Members
0 Resources
19 MeSH Terms
Brain dysfunction in patients with chronic critical illness.
Girard TD
(2012) Respir Care 57: 947-55; discussion 955-7
MeSH Terms: Antipsychotic Agents, Attention Deficit Disorder with Hyperactivity, Chronic Disease, Coma, Comorbidity, Critical Illness, Delirium, Haloperidol, Humans, Hypnotics and Sedatives, Lorazepam
Added September 23, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms