Noise-induced cochlear synaptopathy in rhesus monkeys (Macaca mulatta).
Valero MD, Burton JA, Hauser SN, Hackett TA, Ramachandran R, Liberman MC
(2017) Hear Res 353
: 213-223MeSH Terms: Animals, Auditory Fatigue, Auditory Threshold, Cochlea, Cochlear Diseases, Disease Models, Animal, Evoked Potentials, Auditory, Brain Stem, Hair Cells, Auditory, Hearing, Hearing Loss, Noise-Induced, Macaca mulatta, Noise, Otoacoustic Emissions, Spontaneous, Synapses, Synaptic Transmission, Time FactorsAdded April 3, 2018
16 MeSH Terms
Insm1 promotes neurogenic proliferation in delaminated otic progenitors.
Lorenzen SM, Duggan A, Osipovich AB, Magnuson MA, García-Añoveros J
(2015) Mech Dev 138 Pt 3
: 233-45MeSH Terms: Animals, Cell Differentiation, Cell Proliferation, DNA-Binding Proteins, Ear, Inner, Female, Gene Expression Regulation, Developmental, Hair Cells, Auditory, Inner, Hair Cells, Auditory, Outer, Male, Mice, Mice, Knockout, Mice, Transgenic, Neural Stem Cells, Neurogenesis, Pregnancy, RNA, Messenger, Repressor Proteins, Spiral Ganglion, Transcription Factors, Vestibule, Labyrinth, Zinc FingersAdded November 14, 2015
22 MeSH Terms
Regulation of cochlear convergent extension by the vertebrate planar cell polarity pathway is dependent on p120-catenin.
Chacon-Heszele MF, Ren D, Reynolds AB, Chi F, Chen P
(2012) Development 139
: 968-78MeSH Terms: Animals, Cadherins, Catenins, Cell Polarity, Cochlea, Hair Cells, Auditory, Mice, Mice, Transgenic, Morphogenesis, Nerve Tissue Proteins, Protein Precursors, VertebratesAdded March 28, 2014
12 MeSH Terms
Conservation of hearing and protection of auditory hair cells against trauma-induced losses by local dexamethasone therapy: molecular and genetic mechanisms.
Van De Water TR, Abi Hachem RN, Dinh CT, Bas E, Haake SM, Hoosien G, Vivero R, Chan S, He J, Eshraghi AA, Angeli SI, Telischi FF, Balkany TJ
(2010) Cochlear Implants Int 11 Suppl 1
: 42-55MeSH Terms: Animals, Apoptosis, Auditory Threshold, Cells, Cultured, Dexamethasone, Disease Models, Animal, Down-Regulation, Electrodes, Implanted, GTPase-Activating Proteins, Gene Expression Regulation, Guinea Pigs, Hair Cells, Auditory, Hearing Loss, In Vitro Techniques, Organ of Corti, Random Allocation, Real-Time Polymerase Chain Reaction, Reference Values, Tumor Necrosis Factor-alpha, Up-Regulation, Wounds and InjuriesAdded April 18, 2017
21 MeSH Terms
Dexamethasone protects auditory hair cells against TNFalpha-initiated apoptosis via activation of PI3K/Akt and NFkappaB signaling.
Haake SM, Dinh CT, Chen S, Eshraghi AA, Van De Water TR
(2009) Hear Res 255
: 22-32MeSH Terms: Animals, Apoptosis, Benzyl Compounds, Caspase Inhibitors, Dexamethasone, Dose-Response Relationship, Drug, Hair Cells, Auditory, Hydrocarbons, Fluorinated, In Vitro Techniques, NF-kappa B, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Proto-Oncogene Proteins c-akt, Rats, Rats, Sprague-Dawley, Receptors, Glucocorticoid, Signal Transduction, Tumor Necrosis Factor-alphaAdded April 18, 2017
18 MeSH Terms
Dexamethasone protects organ of corti explants against tumor necrosis factor-alpha-induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes.
Dinh CT, Haake S, Chen S, Hoang K, Nong E, Eshraghi AA, Balkany TJ, Van De Water TR
(2008) Neuroscience 157
: 405-13MeSH Terms: Analysis of Variance, Animals, Animals, Newborn, Apoptosis, Dexamethasone, Gene Expression, Glucocorticoids, Hair Cells, Auditory, Organ Culture Techniques, Organ of Corti, Proto-Oncogene Proteins c-bcl-2, Rats, Rats, Sprague-Dawley, Receptors, Tumor Necrosis Factor, Type I, Time Factors, Tumor Necrosis Factor-alpha, bcl-2-Associated X Protein, bcl-X ProteinAdded April 18, 2017
18 MeSH Terms
Zebrafish TRPA1 channels are required for chemosensation but not for thermosensation or mechanosensory hair cell function.
Prober DA, Zimmerman S, Myers BR, McDermott BM, Kim SH, Caron S, Rihel J, Solnica-Krezel L, Julius D, Hudspeth AJ, Schier AF
(2008) J Neurosci 28
: 10102-10MeSH Terms: Animals, Behavior, Animal, Cell Line, Cells, Cultured, Chemoreceptor Cells, Female, Genetic Carrier Screening, Hair Cells, Auditory, Humans, Ion Channels, Larva, Mechanoreceptors, Molecular Sequence Data, Mustard Plant, Mutation, Plant Oils, TRPA1 Cation Channel, Thermoreceptors, Transient Receptor Potential Channels, Xenopus laevis, Zebrafish, Zebrafish ProteinsAdded September 24, 2013
22 MeSH Terms
Biopolymer-released dexamethasone prevents tumor necrosis factor alpha-induced loss of auditory hair cells in vitro: implications toward the development of a drug-eluting cochlear implant electrode array.
Dinh C, Hoang K, Haake S, Chen S, Angeli S, Nong E, Eshraghi AA, Balkany TJ, Van De Water TR
(2008) Otol Neurotol 29
: 1012-9MeSH Terms: Animals, Animals, Newborn, Biopolymers, Cochlear Implants, Delayed-Action Preparations, Dexamethasone, Hair Cells, Auditory, Hearing Loss, Organ of Corti, Prosthesis Design, Rats, Rats, Sprague-Dawley, Tumor Necrosis Factor-alphaAdded April 18, 2017
13 MeSH Terms
Deafness and imbalance associated with inactivation of the secretory Na-K-2Cl co-transporter.
Delpire E, Lu J, England R, Dull C, Thorne T
(1999) Nat Genet 22
: 192-5MeSH Terms: Animals, Bumetanide, Carrier Proteins, Cochlea, Deafness, Erythrocytes, Hair Cells, Auditory, Outer, Mice, Mice, Knockout, Mice, Neurologic Mutants, Motor Activity, Movement Disorders, Organ of Corti, Potassium, Protein Isoforms, Rabbits, Rats, Restriction Mapping, Sodium, Sodium-Potassium-Chloride SymportersAdded August 13, 2010
20 MeSH Terms