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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 28

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Metabolic Labeling of Inositol Phosphates and Phosphatidylinositols in Yeast and Mammalian Cells.
Hale AT, Clarke BP, York JD
(2020) Methods Mol Biol 2091: 83-92
MeSH Terms: Animals, Biochemical Phenomena, COS Cells, Cell Line, Chlorocebus aethiops, HT29 Cells, HeLa Cells, Humans, Inositol Phosphates, Phosphatidylinositols, Saccharomyces cerevisiae, Signal Transduction
Added March 30, 2020
0 Communities
1 Members
0 Resources
12 MeSH Terms
Direct Activation of Human MLKL by a Select Repertoire of Inositol Phosphate Metabolites.
McNamara DE, Dovey CM, Hale AT, Quarato G, Grace CR, Guibao CD, Diep J, Nourse A, Cai CR, Wu H, Kalathur RC, Green DR, York JD, Carette JE, Moldoveanu T
(2019) Cell Chem Biol 26: 863-877.e7
MeSH Terms: Animals, Cell Survival, HT29 Cells, Humans, Inositol Phosphates, Protein Kinases, Sf9 Cells, Spodoptera
Added March 30, 2020
0 Communities
1 Members
0 Resources
8 MeSH Terms
Critical role of bacterial dissemination in an infant rabbit model of bacillary dysentery.
Yum LK, Byndloss MX, Feldman SH, Agaisse H
(2019) Nat Commun 10: 1826
MeSH Terms: Animals, Animals, Newborn, Colon, Diarrhea, Disease Models, Animal, Dysentery, Bacillary, Epithelial Cells, Female, Gastrointestinal Hemorrhage, HT29 Cells, Humans, Intestinal Mucosa, Pregnancy, Rabbits, Shigella flexneri, Type III Secretion Systems
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Upregulated claudin-1 expression promotes colitis-associated cancer by promoting β-catenin phosphorylation and activation in Notch/p-AKT-dependent manner.
Gowrikumar S, Ahmad R, Uppada SB, Washington MK, Shi C, Singh AB, Dhawan P
(2019) Oncogene 38: 5321-5337
MeSH Terms: Animals, Biomarkers, Tumor, Cells, Cultured, Claudin-1, Colitis, Colonic Neoplasms, Gene Expression Regulation, Neoplastic, HT29 Cells, Humans, Inflammatory Bowel Diseases, Intestinal Mucosa, Mice, Mice, Inbred C57BL, Mice, Transgenic, Phosphorylation, Prognosis, Protein Processing, Post-Translational, Proto-Oncogene Proteins c-akt, Receptors, Notch, Signal Transduction, Up-Regulation, beta Catenin
Added April 24, 2019
1 Communities
0 Members
0 Resources
22 MeSH Terms
MLKL Requires the Inositol Phosphate Code to Execute Necroptosis.
Dovey CM, Diep J, Clarke BP, Hale AT, McNamara DE, Guo H, Brown NW, Cao JY, Grace CR, Gough PJ, Bertin J, Dixon SJ, Fiedler D, Mocarski ES, Kaiser WJ, Moldoveanu T, York JD, Carette JE
(2018) Mol Cell 70: 936-948.e7
MeSH Terms: Binding Sites, Cell Death, Colonic Neoplasms, Gene Expression Regulation, Enzymologic, Gene Expression Regulation, Neoplastic, HT29 Cells, Herpesvirus 1, Human, Humans, Inositol Phosphates, Jurkat Cells, Mutation, Phosphorylation, Phosphotransferases (Alcohol Group Acceptor), Protein Kinases, Receptor-Interacting Protein Serine-Threonine Kinases, Signal Transduction, Tumor Necrosis Factor-alpha
Added March 30, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells.
Chung L, Thiele Orberg E, Geis AL, Chan JL, Fu K, DeStefano Shields CE, Dejea CM, Fathi P, Chen J, Finard BB, Tam AJ, McAllister F, Fan H, Wu X, Ganguly S, Lebid A, Metz P, Van Meerbeke SW, Huso DL, Wick EC, Pardoll DM, Wan F, Wu S, Sears CL, Housseau F
(2018) Cell Host Microbe 23: 203-214.e5
MeSH Terms: Adenomatous Polyposis Coli Protein, Animals, Bacterial Toxins, Bacteroides fragilis, Carcinogenesis, Cell Line, Tumor, Colon, Colorectal Neoplasms, Enzyme Activation, Epithelial Cells, Female, Gene Deletion, HT29 Cells, Humans, Inflammation, Interleukin-17, Male, Metalloendopeptidases, Mice, Mice, Inbred C57BL, Mice, Knockout, Myeloid Cells, Receptors, Interleukin-17, Receptors, Interleukin-8B, STAT3 Transcription Factor, Transcription Factor RelA
Added March 20, 2018
0 Communities
1 Members
0 Resources
26 MeSH Terms
The ErbB3 receptor tyrosine kinase negatively regulates Paneth cells by PI3K-dependent suppression of Atoh1.
Almohazey D, Lo YH, Vossler CV, Simmons AJ, Hsieh JJ, Bucar EB, Schumacher MA, Hamilton KE, Lau KS, Shroyer NF, Frey MR
(2017) Cell Death Differ 24: 855-865
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Communication, Cell Count, Cell Differentiation, Extracellular Signal-Regulated MAP Kinases, Female, Gene Expression Regulation, HT29 Cells, Humans, Ileum, MAP Kinase Signaling System, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Paneth Cells, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Receptor, ErbB-3, Receptors, G-Protein-Coupled, Stem Cell Niche, Stem Cells
Added October 16, 2018
0 Communities
1 Members
0 Resources
MeSH Terms
Targeting Enox1 in tumor stroma increases the efficacy of fractionated radiotherapy.
Smith CA, Mont S, Traver G, Sekhar KR, Crooks PA, Freeman ML
(2016) Oncotarget 7: 77926-77936
MeSH Terms: Animals, Cell Line, Tumor, Colorectal Neoplasms, Dose Fractionation, Radiation, HT29 Cells, Humans, Mice, Mice, Nude, Molecular Targeted Therapy, NADH, NADPH Oxidoreductases, Radiation-Sensitizing Agents, Xenograft Model Antitumor Assays
Added March 17, 2017
0 Communities
2 Members
0 Resources
12 MeSH Terms
Loss of caspase-3 sensitizes colon cancer cells to genotoxic stress via RIP1-dependent necrosis.
Brown MF, Leibowitz BJ, Chen D, He K, Zou F, Sobol RW, Beer-Stolz D, Zhang L, Yu J
(2015) Cell Death Dis 6: e1729
MeSH Terms: Caspase 3, Cell Death, Colonic Neoplasms, DNA Damage, HCT116 Cells, HEK293 Cells, HT29 Cells, Humans, Nuclear Pore Complex Proteins, RNA-Binding Proteins, Transfection
Added July 28, 2015
0 Communities
1 Members
0 Resources
11 MeSH Terms
Claudin-7 expression induces mesenchymal to epithelial transformation (MET) to inhibit colon tumorigenesis.
Bhat AA, Pope JL, Smith JJ, Ahmad R, Chen X, Washington MK, Beauchamp RD, Singh AB, Dhawan P
(2015) Oncogene 34: 4570-80
MeSH Terms: Adenocarcinoma, Adenoma, Animals, Carcinogenesis, Claudins, Colonic Neoplasms, Epithelial Cells, Epithelial-Mesenchymal Transition, HT29 Cells, Humans, MAP Kinase Signaling System, Mice, Nude, Neoplasm Transplantation, Transcriptome, Tumor Burden, rab GTP-Binding Proteins
Added February 19, 2015
0 Communities
2 Members
0 Resources
16 MeSH Terms