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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 43

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New genetic predictors for abacavir tolerance in HLA-B*57:01 positive individuals.
Pavlos R, Deshpande P, Chopra A, Leary S, Strautins K, Nolan D, Thorborn D, Shaefer M, Rauch A, Dunn D, Montaner J, Rachlis A, Almeida CA, Choo L, James I, Redwood AJ, Li Y, Gaudieri S, Mallal SA, Phillips EJ
(2020) Hum Immunol 81: 300-304
MeSH Terms: Allergens, Aminopeptidases, Anti-HIV Agents, Dideoxynucleosides, Drug Hypersensitivity Syndrome, Drug-Related Side Effects and Adverse Reactions, Female, Genetic Association Studies, Genetic Predisposition to Disease, Genotype, HIV Infections, HIV-1, HLA-B Antigens, Humans, Lipopolysaccharide Receptors, Male, Minor Histocompatibility Antigens, Phenotype, Retrospective Studies
Added March 30, 2020
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19 MeSH Terms
Single-cell transcriptomics reveal polyclonal memory T-cell responses in skin with positive abacavir patch test results.
Redwood AJ, Rwandamuriye F, Chopra A, Leary S, Ram R, McDonnell W, Konvinse K, White K, Pavlos R, Koelle DM, Mallal S, Phillips EJ
(2019) J Allergy Clin Immunol 144: 1413-1416.e7
MeSH Terms: Aged, Anti-HIV Agents, Arthralgia, CD8-Positive T-Lymphocytes, Dideoxynucleosides, Drug Hypersensitivity, Drug-Related Side Effects and Adverse Reactions, Gene Expression Profiling, HLA-B Antigens, Headache, Humans, Immunologic Memory, Lymphocyte Activation, Male, Myalgia, Patch Tests, Single-Cell Analysis, Skin
Added March 30, 2020
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18 MeSH Terms
High and variable population prevalence of HLA-B*56:02 in indigenous Australians and relation to phenytoin-associated drug reaction with eosinophilia and systemic symptoms.
Somogyi AA, Barratt DT, Phillips EJ, Moore K, Ilyas F, Gabb GM
(2019) Br J Clin Pharmacol 85: 2163-2169
MeSH Terms: Adolescent, Adult, Aged, Australia, Biological Variation, Population, Cohort Studies, Cytochrome P-450 CYP2C9, Drug Hypersensitivity Syndrome, Female, Gene Frequency, Genetic Predisposition to Disease, Genotyping Techniques, HLA-B Antigens, Humans, Indigenous Peoples, Male, Middle Aged, Phenytoin, Young Adult
Added March 30, 2020
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19 MeSH Terms
Shared Genetic Risk Factors Across Carbamazepine-Induced Hypersensitivity Reactions.
Nicoletti P, Barrett S, McEvoy L, Daly AK, Aithal G, Lucena MI, Andrade RJ, Wadelius M, Hallberg P, Stephens C, Bjornsson ES, Friedmann P, Kainu K, Laitinen T, Marson A, Molokhia M, Phillips E, Pichler W, Romano A, Shear N, Sills G, Tanno LK, Swale A, Floratos A, Shen Y, Nelson MR, Watkins PB, Daly MJ, Morris AP, Alfirevic A, Pirmohamed M
(2019) Clin Pharmacol Ther 106: 1028-1036
MeSH Terms: Adult, Anaplastic Lymphoma Kinase, Carbamazepine, Chemical and Drug Induced Liver Injury, Drug Hypersensitivity, Drug Hypersensitivity Syndrome, Europe, Female, Genetic Predisposition to Disease, Genome-Wide Association Study, HLA-A Antigens, HLA-B Antigens, Humans, Male, Phenotype, Risk Factors, Stevens-Johnson Syndrome
Added March 30, 2020
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17 MeSH Terms
Prevention and Diagnosis of Severe T-Cell-Mediated Adverse Drug Reactions: Are We There Yet?
Redwood A, Trubiano J, Phillips EJ
(2019) J Allergy Clin Immunol Pract 7: 228-230
MeSH Terms: Administration, Cutaneous, Drug Hypersensitivity, HLA-B Antigens, Humans, Skin, T-Lymphocytes
Added March 30, 2020
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MeSH Terms
Controversies in drug allergy: Testing for delayed reactions.
Phillips EJ, Bigliardi P, Bircher AJ, Broyles A, Chang YS, Chung WH, Lehloenya R, Mockenhaupt M, Peter J, Pirmohamed M, Roujeau JC, Shear NH, Tanno LK, Trubiano J, Valluzzi R, Barbaud A
(2019) J Allergy Clin Immunol 143: 66-73
MeSH Terms: Animals, Asian Continental Ancestry Group, Carbamazepine, Dideoxynucleosides, HLA-B Antigens, HLA-B15 Antigen, Humans, Skin Tests, Stevens-Johnson Syndrome
Added March 30, 2020
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MeSH Terms
Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 496 adults from San Diego, California, USA.
Moore E, Grifoni A, Weiskopf D, Schulten V, Arlehamn CSL, Angelo M, Pham J, Leary S, Sidney J, Broide D, Frazier A, Phillips E, Mallal S, Mack SJ, Sette A
(2018) Hum Immunol 79: 821-822
MeSH Terms: Adolescent, Adult, Alleles, California, Female, Gene Frequency, Genotype, Genotyping Techniques, HLA-A Antigens, HLA-B Antigens, HLA-C Antigens, HLA-DP Antigens, HLA-DQ Antigens, HLA-DR Antigens, Histocompatibility Testing, Humans, Linkage Disequilibrium, Male, Middle Aged, Sequence Analysis, DNA, T-Lymphocytes, Young Adult
Added March 30, 2020
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MeSH Terms
Active suppression rather than ignorance: tolerance to abacavir-induced HLA-B*57:01 peptide repertoire alteration.
Phillips EJ, Mallal SA
(2018) J Clin Invest 128: 2746-2749
MeSH Terms: Animals, Dideoxynucleosides, Drug Hypersensitivity, Drug Tolerance, HLA-B Antigens, Mice, Mice, Transgenic, Peptides
Added March 30, 2020
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MeSH Terms
Sequence-based HLA-A, B, C, DP, DQ, and DR typing of 159 individuals from the Worcester region of the Western Cape province of South Africa.
Grifoni A, Sidney J, Carpenter C, Phillips E, Mallal S, Scriba TJ, Sette A, Lindestam Arlehamn CS
(2018) Hum Immunol 79: 143-144
MeSH Terms: Databases, Genetic, Gene Frequency, Genotype, HLA-A Antigens, HLA-B Antigens, HLA-C Antigens, HLA-DQ Antigens, HLA-DR Antigens, Humans, Lymphocyte Activation, Mycobacterium tuberculosis, Sequence Analysis, DNA, South Africa, T-Lymphocytes, Tuberculosis
Added March 30, 2020
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MeSH Terms
Clinical Pharmacogenetics Implementation Consortium Guideline for HLA Genotype and Use of Carbamazepine and Oxcarbazepine: 2017 Update.
Phillips EJ, Sukasem C, Whirl-Carrillo M, Müller DJ, Dunnenberger HM, Chantratita W, Goldspiel B, Chen YT, Carleton BC, George AL, Mushiroda T, Klein T, Gammal RS, Pirmohamed M
(2018) Clin Pharmacol Ther 103: 574-581
MeSH Terms: Anticonvulsants, Carbamazepine, Drug-Related Side Effects and Adverse Reactions, HLA-B Antigens, Humans, Oxcarbazepine, Pharmacogenetics
Added March 30, 2020
0 Communities
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MeSH Terms