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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 206

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The abundant DNA adduct -methyl deoxyguanosine contributes to miscoding during replication by human DNA polymerase η.
Njuma OJ, Su Y, Guengerich FP
(2019) J Biol Chem 294: 10253-10265
MeSH Terms: DNA Adducts, DNA Damage, DNA Repair, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Humans, Molecular Structure
Added March 3, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Allosteric Regulation of Oligomerization by a B Trafficking G-Protein Is Corrupted in Methylmalonic Aciduria.
Ruetz M, Campanello GC, McDevitt L, Yokom AL, Yadav PK, Watkins D, Rosenblatt DS, Ohi MD, Southworth DR, Banerjee R
(2019) Cell Chem Biol 26: 960-969.e4
MeSH Terms: Allosteric Regulation, Amino Acid Metabolism, Inborn Errors, Fibroblasts, Guanosine Triphosphate, Humans, Methylmalonyl-CoA Mutase, Molecular Chaperones, Mutation, Protein Transport, Vitamin B 12
Added March 3, 2020
0 Communities
1 Members
0 Resources
10 MeSH Terms
Human DNA polymerase η accommodates RNA for strand extension.
Su Y, Egli M, Guengerich FP
(2017) J Biol Chem 292: 18044-18051
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Base Pair Mismatch, DNA Primers, DNA Replication, DNA-Directed DNA Polymerase, Deoxyguanosine, Electrophoretic Mobility Shift Assay, Humans, Kinetics, Nucleic Acid Heteroduplexes, Nucleic Acid Hybridization, Oligodeoxyribonucleotides, Oligoribonucleotides, Pyrimidine Dimers, RNA, Recombinant Proteins, Reverse Transcription, Substrate Specificity, Transcription Elongation, Genetic
Added March 14, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
The Role of Biomarkers of Oxidative Stress in Breast Cancer Risk and Prognosis: A Systematic Review of the Epidemiologic Literature.
Lee JD, Cai Q, Shu XO, Nechuta SJ
(2017) J Womens Health (Larchmt) 26: 467-482
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Adult, Biomarkers, Tumor, Breast Neoplasms, Deoxyguanosine, Female, Humans, Middle Aged, Oxidative Stress, Prognosis, Risk Factors, Survival Analysis
Added May 19, 2017
0 Communities
2 Members
0 Resources
12 MeSH Terms
A Conserved Hydrophobic Core in Gαi1 Regulates G Protein Activation and Release from Activated Receptor.
Kaya AI, Lokits AD, Gilbert JA, Iverson TM, Meiler J, Hamm HE
(2016) J Biol Chem 291: 19674-86
MeSH Terms: Enzyme Activation, GTP-Binding Protein alpha Subunits, Gi-Go, Guanosine Diphosphate, Guanosine Triphosphate, Humans, Hydrophobic and Hydrophilic Interactions, Protein Structure, Secondary
Added April 8, 2017
1 Communities
3 Members
0 Resources
7 MeSH Terms
Kinetic analysis of bypass of 7,8-dihydro-8-oxo-2'-deoxyguanosine by the catalytic core of yeast DNA polymerase η.
Xue Q, Zhong M, Liu B, Tang Y, Wei Z, Guengerich FP, Zhang H
(2016) Biochimie 121: 161-9
MeSH Terms: 8-Hydroxy-2'-Deoxyguanosine, Catalytic Domain, DNA-Directed DNA Polymerase, Deoxyguanosine, Kinetics, Pyrimidine Nucleotides
Added March 14, 2018
0 Communities
1 Members
0 Resources
6 MeSH Terms
"Slow" Voltage-Dependent Inactivation of CaV2.2 Calcium Channels Is Modulated by the PKC Activator Phorbol 12-Myristate 13-Acetate (PMA).
Zhu L, McDavid S, Currie KP
(2015) PLoS One 10: e0134117
MeSH Terms: Animals, Calcium Channel Blockers, Calcium Channels, N-Type, Calcium Signaling, Cattle, Cells, Cultured, Chromaffin Cells, Enzyme Activation, Guanosine Diphosphate, HEK293 Cells, Humans, Kinetics, Patch-Clamp Techniques, Protein Kinase C, Recombinant Proteins, Tetradecanoylphorbol Acetate, Thionucleotides
Added November 10, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
DNA polymerases κ and ζ cooperatively perform mutagenic translesion synthesis of the C8-2'-deoxyguanosine adduct of the dietary mutagen IQ in human cells.
Bose A, Pande P, Jasti VP, Millsap AD, Hawkins EK, Rizzo CJ, Basu AK
(2015) Nucleic Acids Res 43: 8340-51
MeSH Terms: DNA, DNA Adducts, DNA-Directed DNA Polymerase, Deoxyguanosine, HEK293 Cells, Humans, Mutagens, Mutation Rate, Quinolines
Added January 7, 2016
0 Communities
1 Members
0 Resources
9 MeSH Terms
Base-Displaced Intercalated Conformation of the 2-Amino-3-methylimidazo[4,5-f]quinoline N(2)-dG DNA Adduct Positioned at the Nonreiterated G(1) in the NarI Restriction Site.
Stavros KM, Hawkins EK, Rizzo CJ, Stone MP
(2015) Chem Res Toxicol 28: 1455-68
MeSH Terms: Circular Dichroism, DNA, Deoxyguanosine, Deoxyribonucleases, Type II Site-Specific, Intercalating Agents, Magnetic Resonance Spectroscopy, Molecular Conformation, Nucleic Acid Conformation, Protons, Quinolines, Spectrophotometry, Ultraviolet
Added January 7, 2016
0 Communities
1 Members
0 Resources
11 MeSH Terms
Structural Basis for Error-Free Bypass of the 5-N-Methylformamidopyrimidine-dG Lesion by Human DNA Polymerase η and Sulfolobus solfataricus P2 Polymerase IV.
Patra A, Banerjee S, Johnson Salyard TL, Malik CK, Christov PP, Rizzo CJ, Stone MP, Egli M
(2015) J Am Chem Soc 137: 7011-4
MeSH Terms: DNA Damage, DNA-Directed DNA Polymerase, Deoxyguanosine, Models, Molecular, Pyrimidines, Sulfolobus solfataricus
Added January 7, 2016
0 Communities
1 Members
0 Resources
6 MeSH Terms