Other search tools

About this data

The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

If you have any questions or comments, please contact us.

Results: 1 to 10 of 53

Publication Record

Connections

Phenome-based approach identifies RIC1-linked Mendelian syndrome through zebrafish models, biobank associations and clinical studies.
Unlu G, Qi X, Gamazon ER, Melville DB, Patel N, Rushing AR, Hashem M, Al-Faifi A, Chen R, Li B, Cox NJ, Alkuraya FS, Knapik EW
(2020) Nat Med 26: 98-109
MeSH Terms: Abnormalities, Multiple, Animals, Behavior, Animal, Biological Specimen Banks, Chondrocytes, Disease Models, Animal, Extracellular Matrix, Fibroblasts, Guanine Nucleotide Exchange Factors, Humans, Models, Biological, Musculoskeletal System, Osteogenesis, Phenomics, Phenotype, Procollagen, Protein Transport, Secretory Pathway, Syndrome, Zebrafish, Zebrafish Proteins
Added January 15, 2020
0 Communities
1 Members
0 Resources
21 MeSH Terms
PREX1 drives spontaneous bone dissemination of ER+ breast cancer cells.
Clements ME, Johnson RW
(2020) Oncogene 39: 1318-1334
MeSH Terms: Animals, Apoptosis, Biomarkers, Tumor, Bone Neoplasms, Breast Neoplasms, Cell Movement, Cell Proliferation, Female, Gene Expression Regulation, Neoplastic, Guanine Nucleotide Exchange Factors, Humans, Mice, Mice, Nude, Receptors, Estrogen, Tumor Cells, Cultured, Xenograft Model Antitumor Assays
Added March 3, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Regulation of Glucose-Dependent Golgi-Derived Microtubules by cAMP/EPAC2 Promotes Secretory Vesicle Biogenesis in Pancreatic β Cells.
Trogden KP, Zhu X, Lee JS, Wright CVE, Gu G, Kaverina I
(2019) Curr Biol 29: 2339-2350.e5
MeSH Terms: Animals, Cyclic AMP, Glucose, Golgi Apparatus, Guanine Nucleotide Exchange Factors, Insulin-Secreting Cells, Male, Mice, Mice, Inbred ICR, Microtubules, Organelle Biogenesis, Secretory Vesicles
Added August 6, 2019
1 Communities
2 Members
0 Resources
12 MeSH Terms
β-Cell-intrinsic β-arrestin 1 signaling enhances sulfonylurea-induced insulin secretion.
Barella LF, Rossi M, Zhu L, Cui Y, Mei FC, Cheng X, Chen W, Gurevich VV, Wess J
(2019) J Clin Invest 129: 3732-3737
MeSH Terms: Animals, Genotype, Glyburide, Guanine Nucleotide Exchange Factors, Hypoglycemic Agents, Insulin Secretion, Insulin-Secreting Cells, Male, Mice, Mice, Knockout, Mice, Transgenic, Phenotype, Signal Transduction, Sulfonylurea Compounds, Tolbutamide, beta-Arrestin 1, beta-Arrestin 2
Added March 18, 2020
0 Communities
1 Members
0 Resources
17 MeSH Terms
A multi-stage genome-wide association study of uterine fibroids in African Americans.
Hellwege JN, Jeff JM, Wise LA, Gallagher CS, Wellons M, Hartmann KE, Jones SF, Torstenson ES, Dickinson S, Ruiz-Narváez EA, Rohland N, Allen A, Reich D, Tandon A, Pasaniuc B, Mancuso N, Im HK, Hinds DA, Palmer JR, Rosenberg L, Denny JC, Roden DM, Stewart EA, Morton CC, Kenny EE, Edwards TL, Velez Edwards DR
(2017) Hum Genet 136: 1363-1373
MeSH Terms: Adult, African Americans, Alleles, Cell Adhesion Molecules, Female, Gene Expression Regulation, Neoplastic, Gene Frequency, Genetic Loci, Genome-Wide Association Study, Guanine Nucleotide Exchange Factors, Humans, Leiomyoma, Middle Aged, Neoplasm Proteins, Risk Factors, Uterine Neoplasms
Added March 14, 2018
0 Communities
4 Members
0 Resources
16 MeSH Terms
The guanine nucleotide exchange factor (GEF) Asef2 promotes dendritic spine formation via Rac activation and spinophilin-dependent targeting.
Evans JC, Robinson CM, Shi M, Webb DJ
(2015) J Biol Chem 290: 10295-308
MeSH Terms: Actin Cytoskeleton, Amino Acid Sequence, Animals, Dendritic Spines, Embryo, Mammalian, Gene Expression Regulation, Developmental, Guanine Nucleotide Exchange Factors, Hippocampus, Microfilament Proteins, Molecular Sequence Data, Nerve Tissue Proteins, Neurogenesis, Primary Cell Culture, Proto-Oncogene Proteins c-akt, RNA, Small Interfering, Rats, Receptors, N-Methyl-D-Aspartate, Signal Transduction, Synapses
Added February 5, 2016
0 Communities
1 Members
0 Resources
19 MeSH Terms
The Rho family GEF Asef2 regulates cell migration in three dimensional (3D) collagen matrices through myosin II.
Jean L, Yang L, Majumdar D, Gao Y, Shi M, Brewer BM, Li D, Webb DJ
(2014) Cell Adh Migr 8: 460-7
MeSH Terms: Cell Line, Cell Movement, Collagen, Guanine Nucleotide Exchange Factors, Heterocyclic Compounds, 4 or More Rings, Humans, Immunohistochemistry, Myosin Type II
Added January 20, 2015
0 Communities
1 Members
0 Resources
8 MeSH Terms
The Cdc15 and Imp2 SH3 domains cooperatively scaffold a network of proteins that redundantly ensure efficient cell division in fission yeast.
Ren L, Willet AH, Roberts-Galbraith RH, McDonald NA, Feoktistova A, Chen JS, Huang H, Guillen R, Boone C, Sidhu SS, Beckley JR, Gould KL
(2015) Mol Biol Cell 26: 256-69
MeSH Terms: Amino Acid Sequence, Cell Cycle Proteins, Cell Division, Cytokinesis, Cytoskeletal Proteins, GTP-Binding Proteins, Gene Regulatory Networks, Guanine Nucleotide Exchange Factors, Immunoblotting, Luminescent Proteins, Microscopy, Confocal, Molecular Sequence Data, Mutation, Protein Binding, Proteome, Proteomics, Schizosaccharomyces, Schizosaccharomyces pombe Proteins, Sequence Homology, Amino Acid, Time-Lapse Imaging, src Homology Domains
Added January 20, 2015
0 Communities
1 Members
0 Resources
21 MeSH Terms
P-REX1 creates a positive feedback loop to activate growth factor receptor, PI3K/AKT and MEK/ERK signaling in breast cancer.
Dillon LM, Bean JR, Yang W, Shee K, Symonds LK, Balko JM, McDonald WH, Liu S, Gonzalez-Angulo AM, Mills GB, Arteaga CL, Miller TW
(2015) Oncogene 34: 3968-76
MeSH Terms: Animals, Breast Neoplasms, Cell Survival, Feedback, Physiological, Female, Guanine Nucleotide Exchange Factors, Humans, MAP Kinase Signaling System, MCF-7 Cells, Mice, Inbred NOD, Mice, SCID, Mutation, Neoplasm Transplantation, Phosphatidylinositol 3-Kinases, Proto-Oncogene Proteins c-akt, Receptors, Growth Factor, rac GTP-Binding Proteins
Added October 21, 2014
0 Communities
2 Members
0 Resources
17 MeSH Terms
Spatial control of Cdc42 signalling by a GM130-RasGRF complex regulates polarity and tumorigenesis.
Baschieri F, Confalonieri S, Bertalot G, Di Fiore PP, Dietmaier W, Leist M, Crespo P, Macara IG, Farhan H
(2014) Nat Commun 5: 4839
MeSH Terms: Antigens, CD, Autoantigens, Cadherins, Carcinogenesis, Cell Line, Tumor, Cell Polarity, Gene Expression Regulation, Neoplastic, Gene Silencing, Humans, MAP Kinase Signaling System, MCF-7 Cells, Membrane Proteins, Mitogen-Activated Protein Kinase 3, Rho Guanine Nucleotide Exchange Factors, Signal Transduction, cdc42 GTP-Binding Protein, ras Guanine Nucleotide Exchange Factors, ras-GRF1
Added April 10, 2018
0 Communities
1 Members
0 Resources
18 MeSH Terms