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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 17

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Pharmacologic Blockade of v1 Integrin Ameliorates Renal Failure and Fibrosis .
Chang Y, Lau WL, Jo H, Tsujino K, Gewin L, Reed NI, Atakilit A, Nunes ACF, DeGrado WF, Sheppard D
(2017) J Am Soc Nephrol 28: 1998-2005
MeSH Terms: Animals, Fibrosis, Guanidines, Kidney, Male, Mice, Receptors, Vitronectin, Renal Insufficiency, Sulfonamides
Added September 27, 2017
0 Communities
1 Members
0 Resources
9 MeSH Terms
TRIzol and Alu qPCR-based quantification of metastatic seeding within the skeleton.
Preston Campbell J, Mulcrone P, Masood SK, Karolak M, Merkel A, Hebron K, Zijlstra A, Sterling J, Elefteriou F
(2015) Sci Rep 5: 12635
MeSH Terms: Alu Elements, Animals, Biomarkers, Tumor, Bone Neoplasms, Cell Line, Tumor, DNA, Neoplasm, Gene Expression Profiling, Genetic Markers, Guanidines, Mice, Mice, Nude, Phenols, RNA, Neoplasm, Real-Time Polymerase Chain Reaction, Reproducibility of Results, Sensitivity and Specificity
Added September 14, 2016
1 Communities
3 Members
0 Resources
16 MeSH Terms
Pharmacological evaluation of SN79, a sigma (σ) receptor ligand, against methamphetamine-induced neurotoxicity in vivo.
Kaushal N, Seminerio MJ, Robson MJ, McCurdy CR, Matsumoto RR
(2013) Eur Neuropsychopharmacol 23: 960-71
MeSH Terms: Animals, Benzoxazoles, Central Nervous System Stimulants, Corpus Striatum, Dopamine, Dopamine Antagonists, Dopamine Plasma Membrane Transport Proteins, Drug Synergism, Fever, Guanidines, Male, Methamphetamine, Mice, Nerve Tissue Proteins, Neurons, Neuroprotective Agents, Neurotoxicity Syndromes, Piperazines, Random Allocation, Receptors, sigma, Serotonin, Serotonin Antagonists, Serotonin Plasma Membrane Transport Proteins
Added July 10, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms
The mouse ortholog of NEIL3 is a functional DNA glycosylase in vitro and in vivo.
Liu M, Bandaru V, Bond JP, Jaruga P, Zhao X, Christov PP, Burrows CJ, Rizzo CJ, Dizdaroglu M, Wallace SS
(2010) Proc Natl Acad Sci U S A 107: 4925-30
MeSH Terms: Amino Acid Sequence, Animals, DNA, DNA Damage, DNA Glycosylases, Endodeoxyribonucleases, Escherichia coli, Gamma Rays, Guanidines, Guanosine, Hydantoins, Kinetics, Mice, Molecular Sequence Data, Mutation, Pyrimidines, Schiff Bases, Sequence Alignment, Sequence Homology, Amino Acid, Spiro Compounds, Substrate Specificity, Valine
Added January 7, 2016
0 Communities
1 Members
0 Resources
22 MeSH Terms
A phase I dose-escalation and pharmacokinetic study of brostallicin (PNU-166196A), a novel DNA minor groove binder, in adult patients with advanced solid tumors.
Lockhart AC, Howard M, Hande KR, Roth BJ, Berlin JD, Vreeland F, Campbell A, Fontana E, Fiorentini F, Fowst C, Paty VA, Lankford O, Rothenberg ML
(2004) Clin Cancer Res 10: 468-75
MeSH Terms: Aged, Antineoplastic Agents, Area Under Curve, Calibration, DNA Damage, Female, Guanidines, Humans, Kinetics, Male, Middle Aged, Models, Chemical, Neoplasms, Pyrroles, Time Factors
Added March 5, 2014
0 Communities
2 Members
0 Resources
15 MeSH Terms
The contribution of protease-activated receptor 1 to neuronal damage caused by transient focal cerebral ischemia.
Junge CE, Sugawara T, Mannaioni G, Alagarsamy S, Conn PJ, Brat DJ, Chan PH, Traynelis SF
(2003) Proc Natl Acad Sci U S A 100: 13019-24
MeSH Terms: Animals, Cerebrovascular Circulation, Disease Models, Animal, Fibrinolysin, Guanidines, Hippocampus, Humans, Hydrolysis, Injections, Intra-Articular, Ischemic Attack, Transient, Male, Mice, Mice, Inbred C57BL, Mice, Knockout, Neurons, Oligopeptides, Phosphatidylinositols, Receptor, PAR-1, Thrombin, Tissue Plasminogen Activator
Added February 19, 2015
0 Communities
1 Members
0 Resources
20 MeSH Terms
Na(+)/H(+) exchange inhibition prevents endothelial dysfunction after I/R injury.
Gumina RJ, Moore J, Schelling P, Beier N, Gross GJ
(2001) Am J Physiol Heart Circ Physiol 281: H1260-6
MeSH Terms: Acetylcholine, Animals, Coronary Circulation, Coronary Vessels, Dogs, Endothelium, Vascular, Guanidines, Heart Ventricles, Hemodynamics, Ischemic Preconditioning, Myocardial, Myocardial Infarction, Myocardial Ischemia, Myocardial Reperfusion, Organ Size, Reperfusion Injury, Sodium-Hydrogen Exchangers, Sulfones
Added February 21, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms
Congeners of N(alpha)-acetyl-L-cysteine but not aminoguanidine act as neuroprotectants from the lipid peroxidation product 4-hydroxy-2-nonenal.
Neely MD, Zimmerman L, Picklo MJ, Ou JJ, Morales CR, Montine KS, Amaranth V, Montine TJ
(2000) Free Radic Biol Med 29: 1028-36
MeSH Terms: Acetylcysteine, Aldehydes, Animals, Brain, Cell Line, Free Radical Scavengers, Guanidines, In Vitro Techniques, Lipid Peroxidation, Magnetic Resonance Spectroscopy, Male, Mitochondria, Neuroprotective Agents, Rats, Rats, Sprague-Dawley
Added September 13, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Inhibition of the Na(+)/H(+) exchanger confers greater cardioprotection against 90 minutes of myocardial ischemia than ischemic preconditioning in dogs.
Gumina RJ, Buerger E, Eickmeier C, Moore J, Daemmgen J, Gross GJ
(1999) Circulation 100: 2519-26; discussion 2469-72
MeSH Terms: Amiloride, Animals, Dogs, Drug Evaluation, Preclinical, Guanidines, Hemodynamics, Hydrogen, Ion Transport, Ischemic Preconditioning, Myocardial, Mesylates, Muscle Proteins, Myocardial Infarction, Myocardial Reperfusion Injury, Sodium, Sodium-Hydrogen Exchangers, Sulfones
Added February 21, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Chronic aminoguanidine attenuates renal dysfunction and injury in aging rats.
Reckelhoff JF, Hennington BS, Kanji V, Racusen LC, Schmidt AM, Yan SD, Morrow J, Roberts LJ, Salahudeen AK
(1999) Am J Hypertens 12: 492-8
MeSH Terms: Aging, Animals, Biomarkers, Blotting, Western, Dinoprost, Disease Models, Animal, Enzyme Inhibitors, F2-Isoprostanes, Follow-Up Studies, Glomerular Filtration Rate, Glomerulosclerosis, Focal Segmental, Glycation End Products, Advanced, Guanidines, Kidney, Lipid Peroxidation, Male, Malondialdehyde, Nitric Oxide Synthase, Nitric Oxide Synthase Type II, Oxidative Stress, Rats, Rats, Sprague-Dawley, Renal Plasma Flow
Added December 10, 2013
0 Communities
1 Members
0 Resources
23 MeSH Terms