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Results: 1 to 10 of 40

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Glucose Regulates Microtubule Disassembly and the Dose of Insulin Secretion via Tau Phosphorylation.
Ho KH, Yang X, Osipovich AB, Cabrera O, Hayashi ML, Magnuson MA, Gu G, Kaverina I
(2020) Diabetes 69: 1936-1947
MeSH Terms: Animals, Cyclic AMP-Dependent Protein Kinases, Cyclin-Dependent Kinase 5, Glucose, Glycogen Synthase Kinase 3, Insulin Secretion, Insulin-Secreting Cells, Mice, Microtubules, Phosphorylation, Protein Kinase C, tau Proteins
Added July 2, 2020
2 Communities
4 Members
0 Resources
12 MeSH Terms
Inhibition of Glycogen Synthase Kinase 3β as a Treatment for the Prevention of Cognitive Deficits after a Traumatic Brain Injury.
Farr SA, Niehoff ML, Kumar VB, Roby DA, Morley JE
(2019) J Neurotrauma 36: 1869-1875
MeSH Terms: Animals, Brain Injuries, Traumatic, Cognitive Dysfunction, Glycogen Synthase Kinase 3 beta, Maze Learning, Mice, Oligonucleotides, Antisense
Added March 12, 2019
0 Communities
1 Members
0 Resources
7 MeSH Terms
Phosphorylation of XIAP at threonine 180 controls its activity in Wnt signaling.
Ng VH, Hang BI, Sawyer LM, Neitzel LR, Crispi EE, Rose KL, Popay TM, Zhong A, Lee LA, Tansey WP, Huppert S, Lee E
(2018) J Cell Sci 131:
MeSH Terms: Amino Acid Motifs, Animals, Apoptosis Regulatory Proteins, Cell Line, Glycogen Synthase Kinase 3, Humans, Intracellular Signaling Peptides and Proteins, Mitochondrial Proteins, Phosphorylation, Protein Binding, Threonine, Wnt Signaling Pathway, Wnt3A Protein, X-Linked Inhibitor of Apoptosis Protein, Xenopus
Added July 6, 2018
0 Communities
2 Members
0 Resources
15 MeSH Terms
GSK3β Interactions with Amyloid Genes: An Autopsy Verification and Extension.
Hohman TJ, Chibnik L, Bush WS, Jefferson AL, De Jaeger PL, Thornton-Wells TA, Bennett DA, Schneider JA
(2015) Neurotox Res 28: 232-8
MeSH Terms: Adaptor Proteins, Signal Transducing, Aged, 80 and over, Aging, Alzheimer Disease, Amyloid, Brain, Cognitive Dysfunction, Cohort Studies, Educational Status, Female, Follow-Up Studies, Gene Expression, Glycogen Synthase Kinase 3, Glycogen Synthase Kinase 3 beta, Humans, Male, Polymorphism, Single Nucleotide, Sex Characteristics, United States
Added February 22, 2016
0 Communities
2 Members
0 Resources
19 MeSH Terms
Activation of β-catenin signalling by TFF1 loss promotes cell proliferation and gastric tumorigenesis.
Soutto M, Peng D, Katsha A, Chen Z, Piazuelo MB, Washington MK, Belkhiri A, Correa P, El-Rifai W
(2015) Gut 64: 1028-39
MeSH Terms: Animals, Cell Line, Tumor, Cell Proliferation, Down-Regulation, Glycogen Synthase Kinase 3, Glycogen Synthase Kinase 3 beta, Growth Inhibitors, Immunohistochemistry, Mice, Mice, Knockout, Peptides, Protein Phosphatase 2, Proto-Oncogene Proteins c-akt, Stomach Neoplasms, Transcriptional Activation, Trefoil Factor-1, beta Catenin
Added February 19, 2015
0 Communities
2 Members
0 Resources
17 MeSH Terms
Interactions between GSK3β and amyloid genes explain variance in amyloid burden.
Hohman TJ, Koran ME, Thornton-Wells TA, Alzheimer's Neuroimaging Initiative
(2014) Neurobiol Aging 35: 460-5
MeSH Terms: Aged, Aged, 80 and over, Alzheimer Disease, Amyloid beta-Peptides, Female, Gene Expression Regulation, Glycogen Synthase Kinase 3, Glycogen Synthase Kinase 3 beta, Humans, Linear Models, Male, Middle Aged, Plaque, Amyloid, Polymorphism, Single Nucleotide, Risk, tau Proteins
Added December 10, 2014
0 Communities
2 Members
0 Resources
16 MeSH Terms
AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues.
Wang HY, Ducommun S, Quan C, Xie B, Li M, Wasserman DH, Sakamoto K, Mackintosh C, Chen S
(2013) Biochem J 449: 479-89
MeSH Terms: Adipocytes, Adipose Tissue, Animals, Blood Glucose, Blotting, Western, Cells, Cultured, Female, GTPase-Activating Proteins, Glucose, Glucose Tolerance Test, Glucose Transporter Type 4, Glycogen Synthase Kinase 3, Humans, Hypoglycemic Agents, In Vitro Techniques, Insulin, Insulin Resistance, Liver, Male, Mice, Mice, Knockout, Muscle, Skeletal, Phosphoenolpyruvate Carboxykinase (GTP), Phosphorylation
Added July 21, 2014
1 Communities
0 Members
0 Resources
24 MeSH Terms
Thr 163 phosphorylation causes Mcl-1 stabilization when degradation is independent of the adjacent GSK3-targeted phosphodegron, promoting drug resistance in cancer.
Nifoussi SK, Vrana JA, Domina AM, De Biasio A, Gui J, Gregory MA, Hann SR, Craig RW
(2012) PLoS One 7: e47060
MeSH Terms: Animals, Antineoplastic Agents, Apoptosis, Blotting, Western, CHO Cells, Cell Line, Tumor, Cisplatin, Cricetinae, Cytarabine, Drug Resistance, Neoplasm, Etoposide, Flow Cytometry, Glycogen Synthase Kinase 3, Humans, Myeloid Cell Leukemia Sequence 1 Protein, Phosphorylation, Protein Stability, Proto-Oncogene Proteins c-bcl-2, Threonine, Vinblastine
Added March 20, 2014
0 Communities
1 Members
0 Resources
20 MeSH Terms
Interaction between the central and peripheral effects of insulin in controlling hepatic glucose metabolism in the conscious dog.
Ramnanan CJ, Kraft G, Smith MS, Farmer B, Neal D, Williams PE, Lautz M, Farmer T, Donahue EP, Cherrington AD, Edgerton DS
(2013) Diabetes 62: 74-84
MeSH Terms: Animals, Brain, Dogs, Female, Glucokinase, Glucose, Glycogen Synthase Kinase 3, Glycogen Synthase Kinase 3 beta, Glycogenolysis, Hypothalamus, Insulin, Liver, Male, Phosphorylation, STAT3 Transcription Factor
Added February 13, 2015
0 Communities
4 Members
0 Resources
15 MeSH Terms
Reconciling the different roles of Gsk3β in "naïve" and "primed" pluripotent stem cells.
Singh AM, Bechard M, Smith K, Dalton S
(2012) Cell Cycle 11: 2991-6
MeSH Terms: Animals, Cell Differentiation, Enzyme Activation, Furans, Gene Expression Regulation, Enzymologic, Glycogen Synthase Kinase 3, Glycogen Synthase Kinase 3 beta, Homeodomain Proteins, Humans, Immunoenzyme Techniques, Mice, Nanog Homeobox Protein, Phosphatidylinositol 3-Kinases, Phosphoinositide-3 Kinase Inhibitors, Phosphorylation, Pluripotent Stem Cells, Proto-Oncogene Proteins c-myc, Pyridines, Pyrimidines, Species Specificity, Wnt Signaling Pathway
Added August 25, 2016
0 Communities
1 Members
0 Resources
21 MeSH Terms