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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 15

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Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation.
Healey DCC, Cephus JY, Barone SM, Chowdhury NU, Dahunsi DO, Madden MZ, Ye X, Yu X, Olszewski K, Young K, Gerriets VA, Siska PJ, Dworski R, Hemler J, Locasale JW, Poyurovsky MV, Peebles RS, Irish JM, Newcomb DC, Rathmell JC
(2021) J Immunol 206: 1127-1139
MeSH Terms: Adult, Alternaria, Animals, Asthma, Biomarkers, Blood Glucose, Bronchoalveolar Lavage Fluid, Case-Control Studies, Cells, Cultured, Dexamethasone, Disease Models, Animal, Drug Synergism, Female, Glucose Transporter Type 1, Glutaminase, Glutamine, Healthy Volunteers, Humans, Immunosuppressive Agents, Lung, Male, Mice, Middle Aged, Primary Cell Culture, Pyroglyphidae, Th17 Cells, Th2 Cells, Young Adult
Added March 26, 2021
3 Communities
1 Members
0 Resources
28 MeSH Terms
Non-canonical roles for metabolic enzymes and intermediates in malignant progression and metastasis.
Williams D, Fingleton B
(2019) Clin Exp Metastasis 36: 211-224
MeSH Terms: ATP Citrate (pro-S)-Lyase, Disease Progression, Energy Metabolism, Fatty Acids, Glucose, Glucose-6-Phosphate Isomerase, Glutaminase, Glutamine, Humans, Isocitrate Dehydrogenase, Neoplasm Metastasis, Neoplasms
Added March 24, 2020
0 Communities
1 Members
0 Resources
MeSH Terms
Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism.
Johnson MO, Wolf MM, Madden MZ, Andrejeva G, Sugiura A, Contreras DC, Maseda D, Liberti MV, Paz K, Kishton RJ, Johnson ME, de Cubas AA, Wu P, Li G, Zhang Y, Newcomb DC, Wells AD, Restifo NP, Rathmell WK, Locasale JW, Davila ML, Blazar BR, Rathmell JC
(2018) Cell 175: 1780-1795.e19
MeSH Terms: Animals, CD8-Positive T-Lymphocytes, Cell Differentiation, Glutaminase, Lymphocyte Activation, Male, Mice, Mice, Transgenic, Th1 Cells, Th17 Cells
Added October 30, 2019
0 Communities
2 Members
0 Resources
MeSH Terms
Mechanism of Hyperkalemia-Induced Metabolic Acidosis.
Harris AN, Grimm PR, Lee HW, Delpire E, Fang L, Verlander JW, Welling PA, Weiner ID
(2018) J Am Soc Nephrol 29: 1411-1425
MeSH Terms: Acidosis, Aldosterone, Amiloride, Ammonia, Animals, Cation Transport Proteins, Diuretics, Glutaminase, Hydrochlorothiazide, Hydrogen-Ion Concentration, Hyperkalemia, Kidney Tubules, Distal, Kidney Tubules, Proximal, Membrane Glycoproteins, Mice, Mice, Knockout, Protein-Serine-Threonine Kinases, Proton-Translocating ATPases, Urinalysis
Added April 3, 2018
0 Communities
1 Members
0 Resources
19 MeSH Terms
The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ.
Edwards DN, Ngwa VM, Wang S, Shiuan E, Brantley-Sieders DM, Kim LC, Reynolds AB, Chen J
(2017) Sci Signal 10:
MeSH Terms: Adaptor Proteins, Signal Transducing, Amino Acid Transport System ASC, Animals, Biomarkers, Tumor, Breast Neoplasms, DNA-Binding Proteins, Disease Models, Animal, Ephrin-A2, Female, Glutaminase, Glutamine, Humans, Intracellular Signaling Peptides and Proteins, Mice, Mice, Knockout, Minor Histocompatibility Antigens, Muscle Proteins, Phosphoproteins, Trans-Activators, Transcription Factors, Tumor Cells, Cultured
Added April 2, 2019
0 Communities
1 Members
0 Resources
21 MeSH Terms
Associations of autoantibodies, autoimmune risk alleles, and clinical diagnoses from the electronic medical records in rheumatoid arthritis cases and non-rheumatoid arthritis controls.
Liao KP, Kurreeman F, Li G, Duclos G, Murphy S, Guzman R, Cai T, Gupta N, Gainer V, Schur P, Cui J, Denny JC, Szolovits P, Churchill S, Kohane I, Karlson EW, Plenge RM
(2013) Arthritis Rheum 65: 571-81
MeSH Terms: Aged, Antibodies, Antinuclear, Arthritis, Rheumatoid, Autoantibodies, Electronic Health Records, European Continental Ancestry Group, Female, GTP-Binding Proteins, Genetic Predisposition to Disease, Genotype, Humans, Hypothyroidism, Iodide Peroxidase, Male, Middle Aged, Peptides, Cyclic, Risk Factors, Seroepidemiologic Studies, Sjogren's Syndrome, Thyroiditis, Transglutaminases
Added May 27, 2014
0 Communities
1 Members
0 Resources
21 MeSH Terms
Glucose-independent glutamine metabolism via TCA cycling for proliferation and survival in B cells.
Le A, Lane AN, Hamaker M, Bose S, Gouw A, Barbi J, Tsukamoto T, Rojas CJ, Slusher BS, Zhang H, Zimmerman LJ, Liebler DC, Slebos RJ, Lorkiewicz PK, Higashi RM, Fan TW, Dang CV
(2012) Cell Metab 15: 110-21
MeSH Terms: B-Lymphocytes, Carbon Isotopes, Cell Hypoxia, Cell Line, Tumor, Cell Proliferation, Cell Survival, Citric Acid, Citric Acid Cycle, Fumarates, Glucose, Glutaminase, Glutamine, Humans, Isotope Labeling, Malates, Oxidation-Reduction, Sulfides, Thiadiazoles
Added March 12, 2014
0 Communities
2 Members
0 Resources
18 MeSH Terms
Identification of autoantibody biomarkers for primary Sjögren's syndrome using protein microarrays.
Hu S, Vissink A, Arellano M, Roozendaal C, Zhou H, Kallenberg CG, Wong DT
(2011) Proteomics 11: 1499-507
MeSH Terms: Antibodies, Antinuclear, Autoantibodies, Biomarkers, Enzyme-Linked Immunosorbent Assay, Histones, Humans, Lupus Erythematosus, Systemic, Protein Array Analysis, Saliva, Sjogren-Larsson Syndrome, Transglutaminases
Added October 15, 2011
0 Communities
1 Members
0 Resources
11 MeSH Terms
Identification of a PP2A-interacting protein that functions as a negative regulator of phosphatase activity in the ATM/ATR signaling pathway.
McConnell JL, Gomez RJ, McCorvey LR, Law BK, Wadzinski BE
(2007) Oncogene 26: 6021-30
MeSH Terms: Adaptor Proteins, Signal Transducing, Ataxia Telangiectasia Mutated Proteins, Cell Cycle Proteins, Cell Line, DNA-Binding Proteins, Glutaminase, Homeostasis, Humans, Intracellular Signaling Peptides and Proteins, Kidney, Phosphoprotein Phosphatases, Phosphorylation, Protein Phosphatase 2, Protein-Serine-Threonine Kinases, Signal Transduction, Transfection, Tumor Suppressor Proteins
Added December 10, 2013
0 Communities
1 Members
0 Resources
17 MeSH Terms
Tau protein is cross-linked by transglutaminase in P301L tau transgenic mice.
Halverson RA, Lewis J, Frausto S, Hutton M, Muma NA
(2005) J Neurosci 25: 1226-33
MeSH Terms: Amino Acid Substitution, Animals, Brain Chemistry, Disease Susceptibility, Mice, Mice, Transgenic, Microscopy, Fluorescence, Molecular Weight, Movement Disorders, Mutation, Missense, Nerve Degeneration, Neurofibrillary Tangles, Point Mutation, Spinal Cord, Structure-Activity Relationship, Transglutaminases, tau Proteins
Added August 27, 2015
0 Communities
1 Members
0 Resources
17 MeSH Terms