Non-canonical roles for metabolic enzymes and intermediates in malignant progression and metastasis.
Williams D, Fingleton B
(2019) Clin Exp Metastasis 36
: 211-224MeSH Terms: ATP Citrate (pro-S)-Lyase, Disease Progression, Energy Metabolism, Fatty Acids, Glucose, Glucose-6-Phosphate Isomerase, Glutaminase, Glutamine, Humans, Isocitrate Dehydrogenase, Neoplasm Metastasis, NeoplasmsAdded March 24, 2020
Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis.
von Wilamowitz-Moellendorff A, Hunter RW, García-Rocha M, Kang L, López-Soldado I, Lantier L, Patel K, Peggie MW, Martínez-Pons C, Voss M, Calbó J, Cohen PT, Wasserman DH, Guinovart JJ, Sakamoto K
(2013) Diabetes 62
: 4070-82MeSH Terms: Animals, Blood Glucose, Glucose, Glucose-6-Phosphate, Glycogen Synthase, Hepatocytes, Homeostasis, Insulin, Liver, Liver Glycogen, Mice, Mice, Transgenic, Muscle, Skeletal, PhosphorylationAdded April 17, 2014
14 MeSH Terms
Bacillus cereus phosphopentomutase is an alkaline phosphatase family member that exhibits an altered entry point into the catalytic cycle.
Panosian TD, Nannemann DP, Watkins GR, Phelan VV, McDonald WH, Wadzinski BE, Bachmann BO, Iverson TM
(2011) J Biol Chem 286
: 8043-8054MeSH Terms: Alkaline Phosphatase, Bacillus cereus, Bacterial Proteins, Catalysis, Catalytic Domain, Crystallography, X-Ray, Glucose-6-Phosphate, Manganese, Phosphotransferases, RibosemonophosphatesAdded March 7, 2014
10 MeSH Terms
Deletion of the gene encoding the islet-specific glucose-6-phosphatase catalytic subunit-related protein autoantigen results in a mild metabolic phenotype.
Wang Y, Martin CC, Oeser JK, Sarkar S, McGuinness OP, Hutton JC, O'Brien RM
(2007) Diabetologia 50
: 774-8MeSH Terms: Alleles, Animals, Autoantigens, Body Weight, Catalysis, Catalytic Domain, Female, Gene Deletion, Glucose-6-Phosphatase, Glucose-6-Phosphate, Humans, Islets of Langerhans, Male, Mice, Mice, Transgenic, ProteinsAdded December 10, 2013
16 MeSH Terms
Inclusion of low amounts of fructose with an intraportal glucose load increases net hepatic glucose uptake in the presence of relative insulin deficiency in dog.
Shiota M, Galassetti P, Igawa K, Neal DW, Cherrington AD
(2005) Am J Physiol Endocrinol Metab 288
: E1160-7MeSH Terms: Animals, Blood Glucose, Dogs, Female, Fructose, Glucagon, Glucose, Glucose-6-Phosphate, Hydrocortisone, Insulin, Lactic Acid, Liver, Male, Postprandial PeriodAdded December 10, 2013
14 MeSH Terms
Portal vein caffeine infusion enhances net hepatic glucose uptake during a glucose load in conscious dogs.
Pencek RR, Battram D, Shearer J, James FD, Lacy DB, Jabbour K, Williams PE, Graham TE, Wasserman DH
(2004) J Nutr 134
: 3042-6MeSH Terms: Alanine, Animals, Arteries, Blood Glucose, Caffeine, Dogs, Epinephrine, Fatty Acids, Nonesterified, Female, Fructosephosphates, Glucagon, Glucose, Glucose Clamp Technique, Glucose-6-Phosphate, Glycerol, Glycogen, Glycogen Phosphorylase, Glycogen Synthase, Infusions, Intravenous, Insulin, Lactic Acid, Liver, Male, Norepinephrine, Portal VeinAdded March 5, 2013
25 MeSH Terms
Defect in glucokinase translocation in Zucker diabetic fatty rats.
Fujimoto Y, Donahue EP, Shiota M
(2004) Am J Physiol Endocrinol Metab 287
: E414-23MeSH Terms: Animals, Biological Transport, Blood Glucose, Carrier Proteins, Diabetes Mellitus, Diabetes Mellitus, Type 2, Glucagon, Glucokinase, Glucose, Glucose-6-Phosphate, Glycogen, Insulin, Intracellular Membranes, Intracellular Signaling Peptides and Proteins, Liver, Male, Muscle, Skeletal, Obesity, Rats, Rats, Zucker, Thinness, Tissue DistributionAdded December 10, 2013
22 MeSH Terms
Hepatic glucokinase is required for the synergistic action of ChREBP and SREBP-1c on glycolytic and lipogenic gene expression.
Dentin R, Pégorier JP, Benhamed F, Foufelle F, Ferré P, Fauveau V, Magnuson MA, Girard J, Postic C
(2004) J Biol Chem 279
: 20314-26MeSH Terms: Acetyl-CoA Carboxylase, Adenoviridae, Animals, Basic Helix-Loop-Helix Leucine Zipper Transcription Factors, Blotting, Northern, CCAAT-Enhancer-Binding Proteins, Carbohydrate Metabolism, Cell Nucleus, Cells, Cultured, DNA-Binding Proteins, Fatty Acid Synthases, Gene Expression Regulation, Glucokinase, Glucose, Glucose-6-Phosphate, Glycogen, Hepatocytes, Immunoblotting, Kinetics, Lipid Metabolism, Liver, Mice, Mice, Inbred C57BL, Mice, Knockout, Mice, Transgenic, Microscopy, Fluorescence, Nuclear Proteins, Pentosephosphates, Proteins, Pyruvate Kinase, RNA, RNA, Messenger, RNA, Small Interfering, Reverse Transcriptase Polymerase Chain Reaction, Signal Transduction, Sterol Regulatory Element Binding Protein 1, Time Factors, Transcription Factors, Transcription, GeneticAdded February 23, 2011
39 MeSH Terms
Identification and characterization of a cDNA and the gene encoding the mouse ubiquitously expressed glucose-6-phosphatase catalytic subunit-related protein.
Boustead JN, Martin CC, Oeser JK, Svitek CA, Hunter SI, Hutton JC, O'Brien RM
(2004) J Mol Endocrinol 32
: 33-53MeSH Terms: Amino Acid Sequence, Animals, COS Cells, Catalytic Domain, Cells, Cultured, Chlorocebus aethiops, Chromosomes, Cloning, Molecular, DNA, Complementary, Glucose-6-Phosphatase, Glucose-6-Phosphate, HeLa Cells, Humans, Islets of Langerhans, Liver, Mice, Molecular Sequence Data, Muscles, Sequence Alignment, Tissue DistributionAdded July 10, 2013
20 MeSH Terms
Effects of hyperglycemia on hepatic gluconeogenic flux during glycogen phosphorylase inhibition in the conscious dog.
Edgerton DS, Cardin S, Neal D, Farmer B, Lautz M, Pan C, Cherrington AD
(2004) Am J Physiol Endocrinol Metab 286
: E510-22MeSH Terms: Amino Acids, Animals, Dihydropyridines, Dogs, Enzyme Inhibitors, Female, Fructosephosphates, Furans, Glucagon, Gluconeogenesis, Glucose, Glucose-6-Phosphate, Glycogen Phosphorylase, Hyperglycemia, Insulin, Lactic Acid, Liver, MaleAdded December 10, 2013
18 MeSH Terms