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Results: 1 to 9 of 9

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Targeting In Vivo Metabolic Vulnerabilities of Th2 and Th17 Cells Reduces Airway Inflammation.
Healey DCC, Cephus JY, Barone SM, Chowdhury NU, Dahunsi DO, Madden MZ, Ye X, Yu X, Olszewski K, Young K, Gerriets VA, Siska PJ, Dworski R, Hemler J, Locasale JW, Poyurovsky MV, Peebles RS, Irish JM, Newcomb DC, Rathmell JC
(2021) J Immunol 206: 1127-1139
MeSH Terms: Adult, Alternaria, Animals, Asthma, Biomarkers, Blood Glucose, Bronchoalveolar Lavage Fluid, Case-Control Studies, Cells, Cultured, Dexamethasone, Disease Models, Animal, Drug Synergism, Female, Glucose Transporter Type 1, Glutaminase, Glutamine, Healthy Volunteers, Humans, Immunosuppressive Agents, Lung, Male, Mice, Middle Aged, Primary Cell Culture, Pyroglyphidae, Th17 Cells, Th2 Cells, Young Adult
Added March 26, 2021
3 Communities
1 Members
0 Resources
28 MeSH Terms
Impaired enolase 1 glycolytic activity restrains effector functions of tumor-infiltrating CD8 T cells.
Gemta LF, Siska PJ, Nelson ME, Gao X, Liu X, Locasale JW, Yagita H, Slingluff CL, Hoehn KL, Rathmell JC, Bullock TNJ
(2019) Sci Immunol 4:
MeSH Terms: Animals, Antineoplastic Agents, Immunological, CD8-Positive T-Lymphocytes, Cell Line, Tumor, Glucose, Glucose Transporter Type 1, Glycolysis, Hepatitis A Virus Cellular Receptor 2, Humans, Immunoglobulin G, Immunotherapy, Adoptive, Lymphocytes, Tumor-Infiltrating, Melanoma, Mice, Inbred C57BL, Phosphopyruvate Hydratase, Programmed Cell Death 1 Receptor
Added March 30, 2020
0 Communities
1 Members
0 Resources
16 MeSH Terms
Estrogen and insulin transport through the blood-brain barrier.
May AA, Bedel ND, Shen L, Woods SC, Liu M
(2016) Physiol Behav 163: 312-321
MeSH Terms: ATP Binding Cassette Transporter, Subfamily B, Member 1, Animals, Blood Vessels, Blood-Brain Barrier, Body Weight, Brain, Dietary Fats, Estrogens, Female, Glucose Transporter Type 1, Insulin, Insulin Resistance, Male, Obesity, Ovariectomy, Rats, Rats, Long-Evans, Synaptophysin
Added March 2, 2017
0 Communities
1 Members
0 Resources
18 MeSH Terms
IL4 receptor α mediates enhanced glucose and glutamine metabolism to support breast cancer growth.
Venmar KT, Kimmel DW, Cliffel DE, Fingleton B
(2015) Biochim Biophys Acta 1853: 1219-28
MeSH Terms: Animals, Breast Neoplasms, Cell Line, Tumor, Cell Proliferation, Female, Glucose, Glucose Transporter Type 1, Glutamine, Humans, Interleukin-4, Mammary Neoplasms, Animal, Membrane Transport Proteins, Mice, Receptors, Interleukin-4
Added September 28, 2015
0 Communities
1 Members
0 Resources
14 MeSH Terms
Chronic cyclic bladder over distention up-regulates hypoxia dependent pathways.
Stephany HA, Strand DW, Ching CB, Tanaka ST, Milne GL, Cajaiba MM, Thomas JC, Pope JC, Adams MC, Brock JW, Hayward SW, Matusik RJ, Clayton DB
(2013) J Urol 190: 1603-9
MeSH Terms: Animals, Disease Models, Animal, Female, Glucose Transporter Type 1, Hypoxia, Mice, Mice, Inbred C57BL, Oxidative Stress, RNA, Real-Time Polymerase Chain Reaction, Up-Regulation, Urinary Bladder, Urinary Bladder Neck Obstruction, Urination
Added December 10, 2013
2 Communities
4 Members
0 Resources
14 MeSH Terms
Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha.
Park SK, Dadak AM, Haase VH, Fontana L, Giaccia AJ, Johnson RS
(2003) Mol Cell Biol 23: 4959-71
MeSH Terms: Animals, Basic Helix-Loop-Helix Transcription Factors, Cell Compartmentation, Cell Hypoxia, Cell Nucleus, Cells, Cultured, Cytoplasm, Embryo, Mammalian, Endothelial Growth Factors, Fibroblasts, Gene Expression Regulation, Glucose Transporter Type 1, Hypoglycemia, Hypoxia-Inducible Factor 1, alpha Subunit, Intercellular Signaling Peptides and Proteins, Ligases, Lymphokines, Mice, Mice, Mutant Strains, Mixed Function Oxygenases, Monosaccharide Transport Proteins, Oxygen, Peptide Hydrolases, Phosphoglycerate Kinase, Proteasome Endopeptidase Complex, Repressor Proteins, Signal Transduction, Trans-Activators, Transcription Factors, Transcription, Genetic, Tumor Suppressor Proteins, Ubiquitin-Protein Ligases, Vascular Endothelial Growth Factor A, Vascular Endothelial Growth Factors, Von Hippel-Lindau Tumor Suppressor Protein
Added August 19, 2013
0 Communities
1 Members
0 Resources
35 MeSH Terms
Alterations in glutamate transporter protein levels in kindling-induced epilepsy.
Miller HP, Levey AI, Rothstein JD, Tzingounis AV, Conn PJ
(1997) J Neurochem 68: 1564-70
MeSH Terms: ATP-Binding Cassette Transporters, Amino Acid Transport System X-AG, Animals, Biological Transport, Blotting, Western, Brain Chemistry, Cerebral Cortex, Epilepsy, Glucose Transporter Type 1, Hippocampus, Kindling, Neurologic, Male, Monosaccharide Transport Proteins, Rabbits, Rats, Rats, Sprague-Dawley
Added February 19, 2015
0 Communities
1 Members
0 Resources
16 MeSH Terms
Role of the C-terminal tail of the GLUT1 glucose transporter in its expression and function in Xenopus laevis oocytes.
Due AD, Qu ZC, Thomas JM, Buchs A, Powers AC, May JM
(1995) Biochemistry 34: 5462-71
MeSH Terms: 3-O-Methylglucose, Amino Acid Sequence, Animals, Biological Transport, Cell Membrane, Female, Glucose Transporter Type 1, Humans, Kinetics, Leucine, Methylglucosides, Monosaccharide Transport Proteins, Mutagenesis, Site-Directed, Oocytes, Protein Structure, Secondary, RNA, Messenger, Recombinant Fusion Proteins, Recombinant Proteins, Sequence Deletion, Xenopus laevis
Added December 10, 2013
0 Communities
1 Members
0 Resources
20 MeSH Terms
A "cysteineless" GLUT1 glucose transporter has normal function when expressed in Xenopus oocytes.
Due AD, Cook JA, Fletcher SJ, Qu ZC, Powers AC, May JM
(1995) Biochem Biophys Res Commun 208: 590-6
MeSH Terms: 3-O-Methylglucose, Animals, Cysteine, Female, Glucose Transporter Type 1, Humans, In Vitro Techniques, Kinetics, Methylglucosides, Monosaccharide Transport Proteins, Mutagenesis, Site-Directed, Oocytes, Structure-Activity Relationship, Sulfhydryl Reagents, Xenopus laevis
Added December 10, 2013
0 Communities
1 Members
0 Resources
15 MeSH Terms