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The publication data currently available has been vetted by Vanderbilt faculty, staff, administrators and trainees. The data itself is retrieved directly from NCBI's PubMed and is automatically updated on a weekly basis to ensure accuracy and completeness.

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Results: 1 to 10 of 79

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Hepatic glucose uptake and disposition during short-term high-fat vs. high-fructose feeding.
Coate KC, Kraft G, Moore MC, Smith MS, Ramnanan C, Irimia JM, Roach PJ, Farmer B, Neal DW, Williams P, Cherrington AD
(2014) Am J Physiol Endocrinol Metab 307: E151-60
MeSH Terms: Animals, Blood Glucose, Diet, High-Fat, Dietary Carbohydrates, Dietary Fats, Dogs, Fructose, Glucokinase, Glucose, Glycerol, Lactic Acid, Liver, Male, Triglycerides
Added June 2, 2014
0 Communities
4 Members
2 Resources
14 MeSH Terms
Glucotoxicity targets hepatic glucokinase in Zucker diabetic fatty rats, a model of type 2 diabetes associated with obesity.
Ueta K, O'Brien TP, McCoy GA, Kim K, Healey EC, Farmer TD, Donahue EP, Condren AB, Printz RL, Shiota M
(2014) Am J Physiol Endocrinol Metab 306: E1225-38
MeSH Terms: Animals, Body Weight, Canagliflozin, Diabetes Mellitus, Type 2, Eating, Glucagon, Glucokinase, Glucose, Glucose Clamp Technique, Glucosides, Hyperglycemia, Hyperinsulinism, Immunohistochemistry, Liver, Male, Obesity, Organ Size, Oxygen Consumption, RNA, Messenger, Rats, Rats, Zucker, Sodium-Glucose Transporter 2, Sodium-Glucose Transporter 2 Inhibitors, Thiophenes
Added February 19, 2015
0 Communities
1 Members
0 Resources
24 MeSH Terms
The effect of unhealthy β-cells on insulin secretion in pancreatic islets.
Pu Y, Lee S, Samuels DC, Watson LT, Cao Y
(2013) BMC Med Genomics 6 Suppl 3: S6
MeSH Terms: Algorithms, Animals, Cell Membrane, Computer Simulation, Cytoplasm, Glucokinase, Glucose, Glycolysis, Humans, Insulin, Insulin Secretion, Insulin-Secreting Cells, Islets of Langerhans, Mitochondria, Models, Biological
Added May 27, 2014
0 Communities
1 Members
0 Resources
15 MeSH Terms
Overnutrition induces β-cell differentiation through prolonged activation of β-cells in zebrafish larvae.
Li M, Maddison LA, Page-McCaw P, Chen W
(2014) Am J Physiol Endocrinol Metab 306: E799-807
MeSH Terms: Animals, Animals, Genetically Modified, Calcium Channels, L-Type, Cell Count, Cell Differentiation, Disease Models, Animal, Embryo, Nonmammalian, Glucokinase, Insulin-Secreting Cells, KATP Channels, Larva, Membrane Potentials, Overnutrition, Potassium Channels, Inwardly Rectifying, Zebrafish
Added April 24, 2014
0 Communities
2 Members
0 Resources
15 MeSH Terms
Type 2 diabetes and congenital hyperinsulinism cause DNA double-strand breaks and p53 activity in β cells.
Tornovsky-Babeay S, Dadon D, Ziv O, Tzipilevich E, Kadosh T, Schyr-Ben Haroush R, Hija A, Stolovich-Rain M, Furth-Lavi J, Granot Z, Porat S, Philipson LH, Herold KC, Bhatti TR, Stanley C, Ashcroft FM, In't Veld P, Saada A, Magnuson MA, Glaser B, Dor Y
(2014) Cell Metab 19: 109-21
MeSH Terms: Animals, Biomarkers, Calcineurin, Cell Death, Cell Proliferation, Congenital Hyperinsulinism, DNA Breaks, Double-Stranded, Diabetes Mellitus, Type 2, Disease Models, Animal, Enzyme Activation, Enzyme Induction, Fasting, Glucagon-Like Peptide 1, Glucokinase, Glucose, Humans, Insulin-Secreting Cells, Membrane Potentials, Mice, Transgenes, Tumor Suppressor Protein p53
Added February 11, 2014
2 Communities
1 Members
1 Resources
21 MeSH Terms
Hepatic glucose metabolism in late pregnancy: normal versus high-fat and -fructose diet.
Coate KC, Smith MS, Shiota M, Irimia JM, Roach PJ, Farmer B, Williams PE, Moore MC
(2013) Diabetes 62: 753-61
MeSH Terms: Animals, Diabetes, Gestational, Diet, High-Fat, Disease Models, Animal, Dogs, Down-Regulation, Female, Fructose, Glucokinase, Glucose, Glucose Intolerance, Glycogen Phosphorylase, Liver Form, Glycogen Synthase, Hyperglycemia, Insulin Resistance, Liver, Liver Glycogen, Maternal Nutritional Physiological Phenomena, Postprandial Period, Pregnancy
Added June 2, 2014
0 Communities
2 Members
0 Resources
20 MeSH Terms
Portal vein glucose entry triggers a coordinated cellular response that potentiates hepatic glucose uptake and storage in normal but not high-fat/high-fructose-fed dogs.
Coate KC, Kraft G, Irimia JM, Smith MS, Farmer B, Neal DW, Roach PJ, Shiota M, Cherrington AD
(2013) Diabetes 62: 392-400
MeSH Terms: Animals, Diet, High-Fat, Dogs, Fructose, Glucokinase, Glucose, Glucose Intolerance, Glycogen Synthase, Hyperglycemia, Hyperinsulinism, Liver, Liver Glycogen, Male, Portal Vein, Signal Transduction
Added December 5, 2013
1 Communities
3 Members
1 Resources
15 MeSH Terms
Interaction between the central and peripheral effects of insulin in controlling hepatic glucose metabolism in the conscious dog.
Ramnanan CJ, Kraft G, Smith MS, Farmer B, Neal D, Williams PE, Lautz M, Farmer T, Donahue EP, Cherrington AD, Edgerton DS
(2013) Diabetes 62: 74-84
MeSH Terms: Animals, Brain, Dogs, Female, Glucokinase, Glucose, Glycogen Synthase Kinase 3, Glycogen Synthase Kinase 3 beta, Glycogenolysis, Hypothalamus, Insulin, Liver, Male, Phosphorylation, STAT3 Transcription Factor
Added February 13, 2015
0 Communities
4 Members
0 Resources
15 MeSH Terms
Clinical assessment of HNF1A and GCK variants and identification of a novel mutation causing MODY2.
Shoemaker AH, Zienkiewicz J, Moore DJ
(2012) Diabetes Res Clin Pract 96: e36-9
MeSH Terms: Adolescent, Diabetes Mellitus, Type 2, Female, Glucokinase, Hepatocyte Nuclear Factor 1-alpha, Humans, Mutation
Added October 24, 2013
0 Communities
2 Members
0 Resources
7 MeSH Terms
Control of pancreatic β cell regeneration by glucose metabolism.
Porat S, Weinberg-Corem N, Tornovsky-Babaey S, Schyr-Ben-Haroush R, Hija A, Stolovich-Rain M, Dadon D, Granot Z, Ben-Hur V, White P, Girard CA, Karni R, Kaestner KH, Ashcroft FM, Magnuson MA, Saada A, Grimsby J, Glaser B, Dor Y
(2011) Cell Metab 13: 440-449
MeSH Terms: Animals, Blood Glucose, Cell Membrane, Cell Proliferation, Glucokinase, Glycolysis, Insulin-Secreting Cells, KATP Channels, Mice, Regeneration
Added January 8, 2012
1 Communities
1 Members
0 Resources
10 MeSH Terms